Low Vit D May Increase Risk of COVID-19 Infection

Node Smith, ND

A new study has found an association between averaging low levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries.

Average low levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries linked in new study

The research, led by Dr Lee Smith of Anglia Ruskin University (ARU) and Mr Petre Cristian Ilie, lead urologist of Queen Elizabeth Hospital King’s Lynn NHS Foundation Trust, is published in the journal Aging Clinical and Experimental Research.

Observational studies have reported an association between low levels of vitamin D and susceptibility to acute respiratory tract infections

Previous observational studies have reported an association between low levels of vitamin D and susceptibility to acute respiratory tract infections. Vitamin D modulates the response of white blood cells, preventing them from releasing too many inflammatory cytokines. The COVID-19 virus is known to cause an excess of pro-inflammatory cytokines.

Italy and Spain have both experienced high COVID-19 mortality rates, and the new study shows that both countries have lower average vitamin D levels than most northern European countries. This is partly because people in southern Europe, particularly the elderly, avoid strong sun, while skin pigmentation also reduces natural vitamin D synthesis.

Highest average levels of vitamin D are found in northern Europe

The highest average levels of vitamin D are found in northern Europe, due to the consumption of cod liver oil and vitamin D supplements, and possibly less sun avoidance. Scandinavian nations are among the countries with the lowest number of COVID-19 cases and mortality rates per head of population in Europe.

‘Significant crude relationship between average vitamin D levels and the number COVID-19 cases’

Dr Lee Smith, Reader in Physical Activity and Public Health at Anglia Ruskin University, said:

We found a significant crude relationship between average vitamin D levels and the number COVID-19 cases, and particularly COVID-19 mortality rates, per head of population across the 20 European countries.

Vitamin D has been shown to protect against acute respiratory infections, and older adults, the group most deficient in vitamin D, are also the ones most seriously affected by COVID-19.

75% of people in institutions, such as hospitals and care homes, were severely deficient in vitamin D

A previous study found that 75% of people in institutions, such as hospitals and care homes, were severely deficient in vitamin D. We suggest it would be advisable to perform dedicated studies looking at vitamin D levels in COVID-19 patients with different degrees of disease severity.”

Mr Petre Cristian Ilie, lead urologist of Queen Elizabeth Hospital King’s Lynn NHS Foundation Trust, said: “Our study does have limitations however, not least because the number of cases in each country is affected by the number of tests performed, as well as the different measures taken by each country to prevent the spread of infection. Finally, and importantly, one must remember correlation does not necessarily mean causation.”

1. Ilie, P. C., et al. (2020) The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clinical and Experimental Research. doi.org/10.1007/s40520-020-01570-8.


Node Smith, ND, is a naturopathic physician in Humboldt, Saskatchewan and associate editor and continuing education director for NDNR. His mission is serving relationships that support the process of transformation, and that ultimately lead to healthier people, businesses and communities. His primary therapeutic tools include counselling, homeopathy, diet and the use of cold water combined with exercise. Node considers health to be a reflection of the relationships a person or a business has with themselves, with God and with those around them. In order to cure disease and to heal, these relationships must be specifically considered. Node has worked intimately with many groups and organizations within the naturopathic profession, and helped found the non-profit, Association for Naturopathic Revitalization (ANR), which works to promote and facilitate experiential education in vitalism.

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