The Impact of High Fructose Diet on Offspring
According to a new study by the Society for Maternal-Fetal Medicine, researchers discuss their findings on the effects of antenatal exposure to a high fructose diet on the offspring’s development of metabolic syndrome-like phenotype and cardiovascular disease later in life.
The mice study was conducted by randomly administering either a fructose solution or water as the only drinking fluid for mice throughout their pregnancy. The offspring were given regular food and evaluated after a year. The researchers measured the visceral adipose tissue, liver fat infiltrates, blood pressure, as well as glucose tolerance. Additionally, serum concentrations of glucose, insulin triglycerides, total cholesterol, leptin, and adiponectin were measured.
The results of the study included a higher peak glucose than compared to the control group. While there were no significant differences seen in the male offspring, the females were heavier and had a higher percent of visceral adipose tissue, liver fat infiltrates, fasting homeostatic model assessment scores, higher serum concentrations of leptin and lower concentrations of adiponectin.
For more information, read the full study.