Metabolic Phenotyping: Testing Urine, Choosing a Diet

Naturopathic News

We want to eat healthier, but what diet is best for us individually? Our urine may help determine the answer. Urinary metabolic phenotyping has been tested as a more accurate way–as opposed to self-reporting–to learn what a body needs to eat to stay healthy. What’s most interesting: a diet that is good for one person may not be good for another. “Diet is a key contributor to human health and disease, though it is notoriously difficult to measure accurately because it relies on an individual’s ability to recall what and how much they ate,” stated study author Joram Posma, PhD, MSC. 

Over 1800 urine samples were analyzed for levels of 46 metabolites. Digestion produces metabolites that show what a patient has consumed–fructose, glucose, nutrients, etc–and provided researchers with a window into the quality of diets. Researchers, publishing their findings in the Nature Food journal, stated, “We investigated the stability of each metabolite over time and showed that the urinary metabolic profile is more stable within individuals than reported dietary patterns.” 

Sources:

Posma JM, Garcia-Perez I, Frost G, et al. Nutriome-metabolome relationships provide insights into dietary intake and metabolism. Nature Food. 2020;1:426-436. https://www.nature.com/articles/s43016-020-0093-y

Moore A. Your urine may help determine your healthiest diet, study finds. MBG Health. October 7, 2024. https://www.mindbodygreen.com/articles/urine-determine-healthy-diet-study-41882a

Advertisement

Current Issue

Table of Contents

The Night Sky Changed Emotional State in 2.5 Minutes

The Night Sky Changed Emotional State in 2.5 Minutes

Night sky photos activated all 6 dimensions of awe, increased positive emotion, and restored mental focus in under 3 minutes. People Who Looked at the Night Sky Felt Vastly Different Within Minutes Photographs of deep space and starry night skies activated all 6...

Advertisement

Trending Articles

Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths

Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths

Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major Cardiology...

Air Pollution Disrupted Menstrual Cycles in Premenopausal Women

Air Pollution Disrupted Menstrual Cycles in Premenopausal Women

Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....

Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems

Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems

The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide it produces to...

Fluoxetine During Development Damaged Hearing and the Brainstem

Fluoxetine During Development Damaged Hearing and the Brainstem

Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory Brain and Left the...

Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth

Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth

Aliso Viejo, CA – December 1, 2025 Metagenics, a leading  doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...

Custom Publishing

IS TYLENOL SAFE DURING PREGNANCY?

IS TYLENOL SAFE DURING PREGNANCY?

Understanding Risk Factors, Not Causation Learn how much Tylenol pregnant women can safely take, what risk factors matter, and why glutathione status—not acetaminophen itself—determines safety during pregnancy.   IN THIS ARTICLE • Key Takeaways: Tylenol Safety...

Featured News