Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
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Trending Case Studies
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
Clinical Commentary: Climate Change, Tick-borne Illness, and the Shifting Landscape of Clinical Practice
Lynn Klassen, ND Carolyn Mukai, ND Rising temperatures and changing habitats are driving the spread of Lyme disease and co-infections into new regions—challenging outdated risk maps, diagnostic tools, and clinical assumptions. Abstract Climate change is expanding the...
Restoring Cellular Integrity: Phospholipid Therapy as a Key Treatment of Refractory Tick-Borne Disease
Melanie Stein, ND A clinical case highlights how intravenous phosphatidylcholine and targeted membrane repair strategies supported lasting recovery in a patient with refractory Lyme and co-infections. Abstract This case describes a 47-year-old female high school...
Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Chris D. Meletis, N.D. Abstract Long COVID and chronic fatigue syndrome (CFS) share overlapping pathophysiological mechanisms, with mitochondrial dysfunction emerging as a central driver of persistent fatigue, cognitive impairment, and multisystem dysregulation....
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Featured Article | 2025
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Case Studies | 2025
Understanding Preeclampsia
How to Reduce Risk in Pregnancy and Prevent Future Cardiovascular Disease By Alexsia Priolo Introduction Pregnancy places significant physiologic stress on the cardiovascular system, prompting structural and hemodynamic changes to manage increased blood volume and...
Adjunctive Treatment of Paroxysmal Atrial Fibrillation
Botanical and Nutrient Therapies By Alexandra Mele, ND This article explores the case of a 76-year-old patient with treatment-resistant paroxysmal atrial fibrillation. It highlights how botanical medicines and nutrient therapies complement conventional care, including...
Allergy / Immunology / Environmental / Toxicology Issues – March 2025 | Volume 20 | Issue 2
Issue Details Volume 20 | Issue No.01Published: Jan 2025Theme: Women’s HealthISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=TfHb8yHXoODbAWSBz3m4Ju&source=wordpress" width="986" height="637"] We are excited to present the official...
The Case of the Man with “Unmasked” Premature Ventricular Contractions
A Case Study By Michael Knapp, ND, DHANP This case study examines the treatment journey of a 72-year-old male with premature ventricular contractions (PVCs) following atrial fibrillation ablation. The article highlights the use of Natrum muriaticum, homeopathic...
Announcing a New Online Digital Library of Primary Sources Unveiled at a Recent Conference
By Jamie Oskin, ND, DTBRm, DHANP This past September 20-22, 2024, we hosted a groundbreaking new conference at Sonoran University in Tempe, Arizona, that was a collaborative project of the American Institute of Homœopathy (AIH), Homœopathic Academy of Naturopathic...
Integrating BioIdentical Hormones and Herbal Protocols
Naturopathic Clinical Pearls By Jannine Krause, ND Hormone Replacement Therapy (HRT) and Bio-Identical HRT (Bio-HRT) are often debated in the medical community, leaving many women confused about their options. This article explores a naturopathic approach that...
Differentiating Perimenopause: Avoiding Diagnostic Pitfalls
By Thara Vayali, ND Exploring the complexities of perimenopause, its clinical challenges, and how naturopathic physicians can differentiate symptoms and address root causes. This article delves into the nuances of perimenopause, outlining its stages, associated...
Autoimmunity, Women, and Relationship to Self
Delve into cultural, emotional, and physiological triggers for self-healing By Nicola Dehlinger, ND Exploring the unique connection between autoimmunity and women’s health, delving into cultural, emotional, and physiological triggers for self-healing. This article...
Archived Case Studies and Featured Content
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Herbal Therapeutic Approaches Demonstrate Significant Impact on Rheumatoid Arthritis
Herbal treatments modulate inflammation, reduce immune dysregulation, and alleviate joint symptoms without significant adverse effects. Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation, joint destruction, and reduced quality of...
Resveratrol–Copper Combination Suppresses Glioblastoma Growth and Restores Immune Function
Tumor proliferation suppressed, immune function restored, and harmful DNA cleared with no adverse reactions reported Glioblastoma multiforme (GBM) remains among the deadliest primary brain cancers, notoriously resistant to current treatments. A 2025 pilot clinical...
Pharmacists Continue to Dispense Antidepressants Despite Hesitation, Study Finds
Pharmacists Fear Discussing Antidepressant Risks, Leaving Patients Uninformed and Overmedicated The Serotonin Theory Has Been Debunked For decades, depression treatments rested on a simple theory: low serotonin caused depression. An expansive, rigorous analysis of...
Stand for Health Freedom Launches National Fluoride Toolkit to Empower Citizens in 48 States – Water Should Hydrate, Not Medicate
May 2025 – Indianapolis, IN — Stand for Health Freedom (SHF) has launched a powerful new resource to support local and state advocates working to end public water fluoridation across the United States. With 48 states still adding fluoride to their water systems, this...
Skin-to-Skin Contact: Science Validates Traditional Wisdom
Maternal Instinct is Rooted in Biology and Expressed Through Culture Throughout history, maternal instinct has consistently highlighted the need for mothers to maintain physical closeness with their newborns. Cultural traditions globally, from China's "zuo yuezi" to...
Anacyclus Pyrethrum in Parkinson’s Disease: A Clinical Exploration of Cognitive Decline
Parkinson’s disease (PD) is often described primarily as a movement disorder, but this definition captures only a fraction of its complexity. The familiar symptoms, tremors, stiffness, and slow movements, are outward signs of a more profound neurological disruption...
Topical Treatments for Rosacea: A Clinical Comparison of Efficacy and Patient Outcomes
Jordan Robertson, ND A detailed evaluation of the most commonly prescribed topical treatments for rosacea, comparing efficacy, patient suitability, and clinical outcomes. Rosacea significantly affects patients' quality of life, and evidence indicates that any...
Mental Health & Insomnia – May 2025 | Volume 20 | Issue 5
Issue Details Volume 20 | Issue No.05Published: May 2025Theme: Mental Health and InsomniaISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=xbnZ815tnZmF3SIlTBBI6f&source=wordpress" width="100%" height="637"]
Physical Punishment Harms Children’s Physical and Neurological Health
Neuroscience Reveals Lasting Damage from Physical Discipline A Comprehensive 2025 Meta-Analysis Reveals Physical Punishment Activates Toxic Stress, Causes Structural Brain Damage, and Leads to Emotional and Behavioral Dysfunction Pain as a Protective Biological Signal...
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
Anacyclus Pyrethrum in Parkinson’s Disease: A Clinical Exploration of Cognitive Decline
Parkinson’s disease (PD) is often described primarily as a movement disorder, but this definition captures only a fraction of its complexity. The familiar symptoms, tremors, stiffness, and slow movements, are outward signs of a more profound neurological disruption...
Topical Treatments for Rosacea: A Clinical Comparison of Efficacy and Patient Outcomes
Jordan Robertson, ND A detailed evaluation of the most commonly prescribed topical treatments for rosacea, comparing efficacy, patient suitability, and clinical outcomes. Rosacea significantly affects patients' quality of life, and evidence indicates that any...
Mental Health & Insomnia – May 2025 | Volume 20 | Issue 5
Issue Details Volume 20 | Issue No.05Published: May 2025Theme: Mental Health and InsomniaISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=xbnZ815tnZmF3SIlTBBI6f&source=wordpress" width="100%" height="637"]
Physical Punishment Harms Children’s Physical and Neurological Health
Neuroscience Reveals Lasting Damage from Physical Discipline A Comprehensive 2025 Meta-Analysis Reveals Physical Punishment Activates Toxic Stress, Causes Structural Brain Damage, and Leads to Emotional and Behavioral Dysfunction Pain as a Protective Biological Signal...
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
Influenza and COVID Vaccines Disrupt Hypothalamic-Pituitary Axis
Vaccine Immune Response Interferes with Female Reproductive Cycle 2025 JAMA Study Reveals Direct Evidence of Neuroendocrine Effects The 2025 study published in JAMA Network Open provides clear evidence that vaccines affect brain regulatory systems. Researchers...
Midlife Movement Determines Brain Aging
Midlife is the time to move more to protect your brain. By your 40s and 50s, measurable changes in brain structure have already begun. Gray matter volume starts to decline. White matter pathways lose integrity. Amyloid plaques, protein deposits linked to Alzheimer’s...
The Integrative Management of Psoriasis
A Case Study in Homeopathy, Nutrition, and Lifestyle Medicine A comprehensive, patient-centered approach to managing psoriasis by addressing root causes through homeopathy, gut health, and metabolic balance. By Marisa Kassimir, ND Introduction and Case Presentation...
Plastic Chemical Exposure Linked to Over 356,000 Cardiovascular Deaths in 2018
DEHP in Plastics Promotes Inflammation and Arterial Damage Leading to Heart Disease Millions handle plastic products daily, including food containers, medical tubing, and water bottles. These common items often contain di-2-ethylhexyl phthalate (DEHP), a chemical used...
Optimizing Healthy Aging for Older Adults
Insights from a Case Series Using a Novel Supplement Regimen Jen Palmer, ND; Joseph M. Keenan, MD Dietary supplements can provide older adults a therapeutic option for maintaining optimal health without relying on prescription drugs. This article summarizes key...
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Featured News
Physical Punishment Harms Children’s Physical and Neurological Health
Neuroscience Reveals Lasting Damage from Physical Discipline A Comprehensive 2025 Meta-Analysis Reveals Physical Punishment Activates Toxic Stress, Causes Structural Brain Damage, and Leads to Emotional and Behavioral Dysfunction Pain as a Protective Biological Signal...
Influenza and COVID Vaccines Disrupt Hypothalamic-Pituitary Axis
Vaccine Immune Response Interferes with Female Reproductive Cycle 2025 JAMA Study Reveals Direct Evidence of Neuroendocrine Effects The 2025 study published in JAMA Network Open provides clear evidence that vaccines affect brain regulatory systems. Researchers...









