Microcirculation: A Foundation of Health

 In Botanical Medicine, Detoxification Medicine, Environmental Medicine, Nature Cure

Robin DiPasquale, ND, RH (AHG)

Microcirculation is defined as the flow of blood through the smallest blood vessels in the body. This includes capillaries, of course, but also arterioles and venules. Enhancing microcirculation in the body will increase oxygen-carrying ability and use, deliver nutrients, remove metabolic waste and toxins, support and strengthen the immune system, and increase adenosine triphosphate production. Increasing microcirculation can enhance the function of all tissues, organs, and glands and can bring a sense of greater overall well-being.

The study of microcirculation has developed into a specialty area in allopathic medicine. A professional organization called The Microcirculatory Society, Inc was founded in 1954 to encourage the exchange and dissemination of information about the microcirculation. The society holds annual meetings and has a monthly journal titled Microcirculation.1

In Traditional Chinese Medicine, the understanding is that “the qi moves the blood; the blood carries the qi.” Qi and blood flow together through the vessels. They are dependent on each other.

As the body ages or develops a chronic disease, the vital qi is diminished. The blood viscosity is increased and becomes more sticky, or agglutinated. In southern Appalachian herbal medicine, this is referred to as “thick blood” and is considered an etiology for many, if not all, chronic diseases. In addition, the spleen is not as effective in removing old damaged blood cells, capillaries are less flexible, and blood cells are more rigid and can be angular shaped, making it more difficult for them to pass through the capillaries. When qi and blood are not in motion, this is considered blood stasis, a Traditional Chinese Medicine diagnosis that is being evaluated relative to chronic diseases, especially those disorders associated with aging.2

In addition to what we do in our daily life to optimize our own innate pumping of the blood through the body, there are multiple modalities of healing that can be used to enhance the microcirculation. Exercise or movement of any form is significant. This can include any type of cardio work, weight training, yoga, tai chi, and so forth. Qi gong, pranayama, and other energy work move qi, so the blood will follow. Acupuncture, massage therapy, laser therapy, and far infrared sauna can all be considered. I am currently using pulsed electromagnetic field application in my practice, which I find amazing in its outcomes.3 This article will focus on herbal medicine and gemmotherapy.

For new blood to be generated, old blood that is not vital must be removed. If blood is not flowing well, you cannot give nourishing supplementation while the pathological influence remains. Move the blood first, and then give the nourishment.4 Herbal medicines and gemmotherapy can be used for moving blood stasis and for nourishing blood.

There are a group of herbal constituents that best support circulation. Phenolic compounds, especially flavonoids, are found extensively in brightly colored fruits and vegetables; they correct capillary fragility and are important in microcirculation. The anthocyanins are the red, blue, and purple flavonoid-related compounds, also key in enhancing capillary strength.5 The sesquiterpenes are 15-carbon terpenoids that seem to act as anti-inflammatory agents, tonifying muscles and nerves and strengthening connective tissue.6 The pungent principles seem to increase circulation through an increase in catecholamine secretion, especially adrenaline from the adrenal medulla, with the effect of stimulating the metabolism.7

Herbal Action Groups

In supporting circulation with herbal medicine, consider the following herbal action groups, with some examples of herbs to choose from. These can be used as simples or in formula.

Warming herbs increase peripheral flow and perfusion. These include Capsicum frutescens (cayenne), Zingiber officinale (ginger), Zanthoxyllum americanum (prickly ash), Piper nigrum (pepper), and Allium sativum (garlic).

Alteratives are blood purifiers and blood cleansers. These include Arctium lappa (burdock), Rumex crispus (yellow dock), Iris versicolor (blue flag), Scrophularia nodosa (figwort), Smilax species (sarsaparilla), and Trifolium pratense (red clover).

Diaphoretics eliminate toxins and fluid via perspiration through the skin. These include Eupoatorium perfoliatum (boneset), Achillea millefolium (yarrow), Sambucus nigra (elderberry flowers), Z officinale (ginger), Mentha piperita (peppermint), and Cinnamomum cassia (cinnamon)

Diuretics eliminate toxins and fluid through the kidneys and bladder. These include Taraxacum officinale (dandelion leaf), Juniperus communis (juniper), Petroselinum crispum (parsley), and Zea mays (corn silk).

Lymphatics keep lymph fluid in motion. These include Calendula officinalis (marigold), Galium aparine (cleavers), and Phytolacca americana (poke).

Venous support may be obtained from the following: Sorbus species (service tree), Hamamelis virginiana (witch hazel), Aesculus hippocastanum (horse chestnut), and Ruscus aculeatus (butcher’s broom).

Capillary wall and connective tissue integrity may be enhanced by the following: Equisetum arvense (horsetail), Centella asiatica (gotu kola), Vaccinium myrtillus (bilberry), Pinus species (oligomeric proanthocyanidin complexes in pine bark), and Vitis vinifera (oligomeric proanthocyanidin complexes in grape seed).

To treat blood stasis by invigorating and moving the blood,8 try the following: Ligusticum wallichii (lovage), Salvia miltiorrhiza (Chinese red sage), Curcuma longa (turmeric), Leonurus heterophyllus (Chinese motherwort), Rosa chinensis (Chinese tea rose) (or any rose will work here), Boswellia carterii (frankincense), and Commiphora myrrha (myrrh).

Blood tonics are warming, nutritive, and high in minerals.8 These include the following: Rehmannia glutinosa (Chinese foxglove) cooked in wine, Polygonum multiflorum (black-haired Mr He), Angelica sinensis (dang quai), Paeonia lactiflora (white peony), Lycium chinense (wolfberry), and Euphoria longan (longan fruit).

A Few Specific Herbs to Consider Working With

In any circumstances that require more effective circulation, begin at the pump, the heart. The following are a few specific herbs to consider working with.

Crataegus species (hawthorn) will increase the contractility of the heart muscle. This has positive inotropic and negative chronotropic actions, increasing the output of blood with each pump of the heart and the movement of blood through the entire system. The flowers have more flavonoids than the berries, although both are used. Another heart herb to consider is Terminalia arjuna (arjuna). The flavonoids act as anti-inflammatory agents, and the glycosides are cardiotonic. Terminalia arjuna also has positive inotropic action.

Salvia miltiorrhiza (dan shen [Chinese red sage root]) is bitter and slightly cold and enters the channels of the heart and liver: “It quickens the blood, moves the blood, and regulates transportation of blood fluid. The Da Ming [Mingyi Bielu, circa 500 ad] and Ri Hua [Rihuazi Bencao, 713 ad] refer to this as ‘eliminating stasis and engendering the new,’ with the implication of freeing and supplementing.”9 Salvia miltiorrhiza can move blood stasis and can nourish blood.

Polygonum cuspidatum is an invasive plant with big medicine. It is high in reservatrol, a major antioxidant-acting compound being used to assist in chronic conditions, such as heart disease, diabetes, arthritis, and cancer.10

Pycnogenol-containing herbs, including Pinus species (pine bark) and V vinifera (grape seed), are powerful antioxidants. They have specificity for rebuilding collagen, enhancing elasticity and resiliency, and strengthening capillary vessels. Centella asiatica (gotu kola) can also be considered one of the top herbal choices for enhancing the function of connective tissue.

A Gemmotherapy Group to Consider Working With

Gemmotherapy is a collection of plant extracts made from the bud or new growth of plants, mostly trees.11 The embryonic plant parts contain growth hormones and enzymes that are unavailable in the adult plant. These remedies can assist in the regeneration of organ and tissue structure and function through their herbal actions. They can be used individually, grouped together, or combined into formulas.

Sorbus domestica (service tree) is a regulator of venous circulation, decreasing serum viscosity, moving congestion, and tonifying venous walls. It works well in combination with Castanea vesca (sweet chestnut) in moving lymph channels. Aesculus hippocastanum (horse chestnut) contains aescin, a saponin complex, as well as the flavonoids quercetin and epicatchin, all strengthening the venous connective tissue. When used in combination with liver-moving gemmotherapies, venous circulation is facilitated. For lower leg circulation, Populus nigra (black poplar) modulates inflammation. Vaccinium myrtillus (bilberry), whether used as a food, herb, or gemmotherapy, improves microcirculation through the actions of the anthocyanidines, resveratrol, and many other flavonoids.

Thinning the blood viscosity can be one of the more important mechanisms in enhancing microcirculation, especially because thick blood is linked specifically to the development and complications of most chronic diseases. Cornus sanguinia (dogwood) acts as an anticoagulant, used for sticky or thick platelets or elevated platelet counts. It contains betulinic acid, as does Betula pubescens (white birch), which acts as a detergent, facilitating drainage of the entire vascular system. Although Citrus limonum (lemon twig) is considered an adjuvant remedy in support of other stronger and longer-acting gemmotherapy remedies, it increases blood flow quickly, enhancing circulation in all organ systems.

As support remedies, Cercis siliquastrum (Judas tree) has antisclerotic and anticoagulant action, and Syringa vulgaris (lilac) acts as an antispasmodic, facilitating vasodilation, especially of the coronary and carotid arteries. Syringa vulgaris is dosed very low initially to prevent too rapid of perfusion to these vital organs.

Alnus glutinosa (European alder) and Alnus incana (gray alder) are inflammation modulators, antioxidants, and anticoagulants. They decrease capillary fragility and have the potential to increase circulation by initiating angiogenesis.

Vitis vinifera (grape seed) and Pinus montana (mountain pine) contain pycnogenols, some of the more potent antioxidants in our medicinary. The gemmotherapy preparation of Crataegus oxycanthus (hawthorn) encompasses all the heart and circulatory system support of the herbal preparations, and when using gemmotherapy, the healing properties of the flower and fruit are both present in the extraction of the bud.

Via the ginkogolides and bilobalides, Ginkgo biloba (ginkgo) increases cerebral circulation and peripheral circulation, thins the blood by anticoagulant action, and dilates blood vessels, overall increasing blood flow and circulation throughout the body. Although Rosmarinus officinalis (rosemary) is considered primarily a liver and gallbladder gemmotherapy source with its antispasmodic, hepatoprotective, and cholagogue and choleretic actions, the flavonoids modulate inflammation, and the potent volatile oils move stagnant chi, enhancing microcirculation.

Gemmotherapy using Tilia tomentosa (linden), which also has the name Tilia cordata, is a gentle but powerful cardiac remedy. It primarily influences the nervous system to address rapid heart rate and an overall sense of anxiety, which can limit circulation to the heart and throughout the entire cardiovascular system.

DiPasquale_headshotRobin DiPasquale, ND, RH (AHG) earned her degree in naturopathic medicine from Bastyr University in 1995 where, following graduation she became a member of the didactic and clinical faculty. For the past eight years she has served at Bastyr as department chair of botanical medicine, teaching and administering to both the naturopathic program and the bachelor of science in herbal sciences program. Dr. DiPasquale is a clinical associate professor in the department of biobehavioral nursing and health systems at the University of Washington in the CAM certificate program. She loves plants, is published nationally and internationally, and teaches throughout the U.S. and in Italy on plant medicine. She is an anusara-influenced yoga instructor, teaching the flow of yoga from the heart. She currently has a general naturopathic medical practice in Madison, Wis., and is working with the University of Wisconsin Integrative Medicine Clinic as an ND consultant.


  1. The Microcirculatory Society, Inc. News. http://microcirc.org. Accessed August 24, 2011.
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  3. BEMER 3000 pulsed electromagnetic field application (PEMF). http://www.bemeramerica.com. Accessed August 24, 2011.
  4. Dharmananda S. Salvia and the history of microcirculation research in China. http://www.itmonline.org/arts/salvia.htm. Accessed August 24, 2011.
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  10. Zhao KS, Wu KY, Tian Y, et al. The effect of Polygonum cuspidatum on the microcirculation in burned skin. In: Chang HM, Yeung WH, Tso WW, Koo A, eds. Advances in Chinese Medicinal Materials Research. Philadelphia, PA: World Scientific; 1984:591-595.
  11. DiPasquale R. Introductory Training Manual: Gemmotherapy. New York, NY: Gemmos LLC; 2011.
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