Humaira Quraishi, ND, MS Docere Who would ever think we'd be consuming herbicide/pesticides in foods other than fruits, vegetables, and grains? Well, think again. Glyphosate, an herbicide contained in the popular product Roundup, and used to eradicate unwanted...
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Table of Contents | 2018
Antioxidants for Female Infertility: A Review of the Literature
Erica Nikiforuk, BSc, ND, RAc Tolle Causam Infertility, defined as trying to conceive for over 1 year with no success,1 affects as many as 16% of Canadian couples.2 While the cause of infertility is not always identified, it is important to assess for both female and...
The Lymphatic System: A Critical Factor in Female Hormonal Balance
Ginger Nash, ND Tolle Totum I’ve been treating women with hormone imbalances for 20 years, but it’s only within the last 7 or so years that I’ve become mildly obsessed with the lymphatic system. This began when I starting using whole-body regulation thermography and...
Testing Blood Insulin: How This Hormone Shows a Way to Health & Longevity
Richard Maurer, ND Docere “What is the single most helpful blood test, beyond what is usually done, that I can ask my doctor to order for me?” I received this question following my recent presentation on blood test results to guide athletes toward better training,...
The Fourth Trimester
Molly Jarchow, ND, LM Naturopathic Perspective Around the world, the Fourth Trimester has been acknowledged as a special time for both mom and baby that requires extra care and attention. Most often, the Fourth Trimester has been defined as the first 3 months after...
Nigella Sativa: A Powerful Adjunct to Comprehensive Hashimoto’s Treatment
Kaycie Rosen Grigel, ND Vis Medicatrix Naturae Nigella sativa, a lovely plant native to the Middle East, is currently gaining increased attention throughout the world for its ability to decrease inflammation and improve patient outcomes for many chronic disease...
Ovarian Factor Infertility: Workup & Natural Medicine Approach
Corina Dunlap, ND, MS Tolle Causam One of the hardest and most important aspects of supporting individuals and couples with infertility is correct identification and diagnosis of all potential causes (“factors”). Most infertility factors fall into the categories of...
Questions in the Queue: What our Deans Might Not Know Yet
David J. Schleich, PhD Education At a recent educational leadership conference in New York, one keynoter among 3 that weekend said, "Our faculty and their deans often don't know what they don't know, and that is a really big problem in our time." Robust applause...
An Elemental Primer: Use of Elemental Diets in IBD and IBS – Part 1
Gary Weiner, ND, LAc Naturopathic Perspective The elemental diet (ED) has enjoyed a revival in the naturopathic community largely due to the efforts of Drs Allison Siebecker and Steven Sandberg-Lewis, who have consistently presented it as 1 of 4 treatment options for...
Probiotics in IBS
Keegan Sheridan, ND Docere Irritable bowel syndrome (IBS) is a functional disorder characterized by recurring abdominal pain and discomfort, as well as alterations in bowel habits without demonstrable pathology.1 It is prevalent in the developed world, with 10-15% of...
NAFLD: Hepatic Manifestation of Metabolic Syndrome
Asia Muhammad, ND Tolle Causam Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome (MetS). NAFLD (also referred to as NASH, or non-alcoholic steatohepatitis) constitutes a spectrum of simple steatosis, steatohepatitis, and...
CD vs NCGS – My Patient Tested Negative for Celiac – Now What?
McKenzie Treloar Mescon, ND Tolle Totum I am sure I am not alone that patients seek my help in understanding their reaction to gluten when they have tested negative for celiac disease. This article is a summary of my efforts to clear the haze around gluten sensitivity...
The COHERENT Method
Matt Marturano, ND Tolle Totum A Biopsychosocial Approach to Functional Digestive Disorders Since the release of the Rome IV criteria and a series of articles in a special issue of Gastroenterology (Volume 150, Issue 6, May 2016), there has been an upsurge in interest...
Hydrogen Sulfide Dysbiosis: A Case Study
Nirala Jacobi, BHSc, ND Naturopathic Perspective “Mary,” a 65-year-old woman, was referred to me for further treatment for small intestinal bacterial overgrowth (SIBO). She had been given the diagnosis of SIBO in 2015 following a lactulose breath test, and despite...
Micropathology of SIBO: Bridging a Gap Between Research & Clinical Practice
Manoji-Tharaka Gamaralalage, BScChris Hergesheimer, BA, MAKarrin Fairman-Young, ND Tolle Causam Abstract The human-gut microbiome is illuminated as a multifactorial signature of aging and a modulator of health and disease. Small intestinal bacterial overgrowth (SIBO)...
Archived Case Studies and Featured Content
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
Akkermansia muciniphila: Clinical Insights on a Next-Generation Probiotic
Sara Love, ND A clinician’s guide to when—and when not—to use A. muciniphila: evidence for gut-barrier support, metabolic and immune effects, pasteurized vs live formulations, and patient selection. Abstract Akkermansia muciniphila is an emerging “next-generation”...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
Clinical Commentary: Climate Change, Tick-borne Illness, and the Shifting Landscape of Clinical Practice
Lynn Klassen, ND Carolyn Mukai, ND Rising temperatures and changing habitats are driving the spread of Lyme disease and co-infections into new regions—challenging outdated risk maps, diagnostic tools, and clinical assumptions. Abstract Climate change is expanding the...
Restoring Cellular Integrity: Phospholipid Therapy as a Key Treatment of Refractory Tick-Borne Disease
Melanie Stein, ND A clinical case highlights how intravenous phosphatidylcholine and targeted membrane repair strategies supported lasting recovery in a patient with refractory Lyme and co-infections. Abstract This case describes a 47-year-old female high school...
Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Chris D. Meletis, N.D. Abstract Long COVID and chronic fatigue syndrome (CFS) share overlapping pathophysiological mechanisms, with mitochondrial dysfunction emerging as a central driver of persistent fatigue, cognitive impairment, and multisystem dysregulation....
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Featured News
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Naturopathic Doctor Continues Walk Across USA for Health Equity
Fargo, ND - Dennis Godby, 69, ND, MA, a Sacramento, CA-Licensed Naturopathic Doctor (ND), to raise awareness across the USA of significant health disparities, and support the “Health Equity,” movement, will continue his inspiring 756 mile walking trek across America...
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