NODE SMITH, ND Like so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short and long sleepers experienced greater cognitive decline than people who slept a moderate amount, even when the effects of early...
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Table of Contents | 2021
The NDNR Physician’s Choice Awards
https://vimeo.com/639182689 The NDNR Physician’s Choice Awards are bestowed upon companies that embrace naturopathic medicine and support naturopathic physicians, their practices, and patients. In the Fall of 2021, naturopathic doctors selected one company for each of...
Motivating People to Exercise with Messages of Death and Illness
NODE SMITH, ND Fitness apps that emphasize illness- or death-related messaging are more likely to be effective in motivating participation than are social stigma, obesity, or financial cost messaging, according to a recent study. Previous studies, especially on...
Air Pollution & Heart Failure: Hospital Readmissions Show Clear Link
JACOB SCHOR, ND, FABNO Consider how cause and effect might apply to mouse traps. It is easy to assume that mouse traps are associated with greater murine mortality, and based on this, you might advise mice to avoid them. The association is clearly...
Wired for Self-Healing- Part 3
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Integrative Tobacco Cessation: A Case Study
JULIE RHODES, ND, MS Tobacco use is still the leading cause of preventable disease and death in the United States.1 According to the Centers for Disease Control and Prevention (CDC), approximately 20.8% of...
Think Beets, Not Meat! Vegetarian Diets and Cardiovascular Health
STEPHEN W. PARCELL, ND There is good scientific data supporting the role of diet in the prevention of disease, especially cardiovascular disease. Many of the foods we grew up eating – foods that are a part of our cultural food...
Biological Age Reversal: A Research Study from NUNM’s Helfgott Research Institute
NODE SMITH, ND An exciting new research study was recently conducted by our very own naturopathic medical research facility, NUNM’s Helfgott Research Institute, in Portland, Oregon.1 The study, which was published on April...
Notes from the Field: April, 2021
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Age-Related Diseases: Genetics Load the Gun, Lifestyle Pulls the Trigger
CHRIS D. MELETIS, ND In its simplest terms, aging can be explained by the concept of the wear-and-tear of life exceeding the repair. This is often how I start the conversation with patients as we journey into the concepts of biological...
Association Spotlight: The Naturopathic Orthopedic Medicine Academy
TERRANCE MANNING II, ND, RMSK SAMUEL G. OLTMAN, ND Whether one is a primary-care naturopathic physician in a state with a limited scope or a long-time naturopathic prolotherapist practicing in a state with a broad scope, there is a need within...
CBD and the Heart
JAKE F. FELICE, ND, LMP For several months now, I have been writing about the endocannabinoid system (ECS), the many physiologic processes it influences in the body, and how imbalances in the system can result in dysfunction that impacts clinical...
Too Much Free Time May Lead to Lower Sense of Well-Being
NODE SMITH, ND As an individual's free time increases, so does that person's sense of well-being -- but only up to a point. Too much free time can be also be a bad thing, according to research published by the American Psychological Association. "People often complain...
Intracrine Steroid Biosynthesis
ANDREW L. RUBMAN, ND, FABNE SUSAN GORDON, PHD, LMT In the May 2021 issue of NDNR, Carrie Decker, ND, wrote an excellent article titled “The Anti-Aging Effects of DHEA.”1 The present article also discusses...
Epigenetics: Growing Up in a Toxic World – Part 2
CHRIS D. MELETIS, ND Abstract In Part II of this series on pediatric epigenetics, Dr. Chris Meletis explores how modern environmental exposures—including stress, sedentary lifestyles, EMFs, and widespread toxins—can lead to harmful epigenetic modifications that...
Archived Case Studies and Featured Content
D Laura Chan Discusses The Fertility Factor No One Talks About: Men’s Energetic Health
Emma Pollon McLeod The importance of Communication between Naturopathic Doctors and Pharmacist
Pamela Frank Micronutrient Deficiencies and Glucose Dysregulation
Lara Briden A Troubleshooting Approach to Insulin Resistance
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract This...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
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Featured News
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
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