NODE SMITH, ND Like so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short and long sleepers experienced greater cognitive decline than people who slept a moderate amount, even when the effects of early...
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Table of Contents | 2021
The NDNR Physician’s Choice Awards
https://vimeo.com/639182689 The NDNR Physician’s Choice Awards are bestowed upon companies that embrace naturopathic medicine and support naturopathic physicians, their practices, and patients. In the Fall of 2021, naturopathic doctors selected one company for each of...
Motivating People to Exercise with Messages of Death and Illness
NODE SMITH, ND Fitness apps that emphasize illness- or death-related messaging are more likely to be effective in motivating participation than are social stigma, obesity, or financial cost messaging, according to a recent study. Previous studies, especially on...
Air Pollution & Heart Failure: Hospital Readmissions Show Clear Link
JACOB SCHOR, ND, FABNO Consider how cause and effect might apply to mouse traps. It is easy to assume that mouse traps are associated with greater murine mortality, and based on this, you might advise mice to avoid them. The association is clearly...
Wired for Self-Healing- Part 3
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Integrative Tobacco Cessation: A Case Study
JULIE RHODES, ND, MS Tobacco use is still the leading cause of preventable disease and death in the United States.1 According to the Centers for Disease Control and Prevention (CDC), approximately 20.8% of...
Think Beets, Not Meat! Vegetarian Diets and Cardiovascular Health
STEPHEN W. PARCELL, ND There is good scientific data supporting the role of diet in the prevention of disease, especially cardiovascular disease. Many of the foods we grew up eating – foods that are a part of our cultural food...
Biological Age Reversal: A Research Study from NUNM’s Helfgott Research Institute
NODE SMITH, ND An exciting new research study was recently conducted by our very own naturopathic medical research facility, NUNM’s Helfgott Research Institute, in Portland, Oregon.1 The study, which was published on April...
Notes from the Field: April, 2021
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Age-Related Diseases: Genetics Load the Gun, Lifestyle Pulls the Trigger
CHRIS D. MELETIS, ND In its simplest terms, aging can be explained by the concept of the wear-and-tear of life exceeding the repair. This is often how I start the conversation with patients as we journey into the concepts of biological...
Association Spotlight: The Naturopathic Orthopedic Medicine Academy
TERRANCE MANNING II, ND, RMSK SAMUEL G. OLTMAN, ND Whether one is a primary-care naturopathic physician in a state with a limited scope or a long-time naturopathic prolotherapist practicing in a state with a broad scope, there is a need within...
CBD and the Heart
JAKE F. FELICE, ND, LMP For several months now, I have been writing about the endocannabinoid system (ECS), the many physiologic processes it influences in the body, and how imbalances in the system can result in dysfunction that impacts clinical...
Too Much Free Time May Lead to Lower Sense of Well-Being
NODE SMITH, ND As an individual's free time increases, so does that person's sense of well-being -- but only up to a point. Too much free time can be also be a bad thing, according to research published by the American Psychological Association. "People often complain...
Intracrine Steroid Biosynthesis
ANDREW L. RUBMAN, ND, FABNE SUSAN GORDON, PHD, LMT In the May 2021 issue of NDNR, Carrie Decker, ND, wrote an excellent article titled “The Anti-Aging Effects of DHEA.”1 The present article also discusses...
Epigenetics: Growing Up in a Toxic World – Part 2
CHRIS D. MELETIS, ND Abstract In Part II of this series on pediatric epigenetics, Dr. Chris Meletis explores how modern environmental exposures—including stress, sedentary lifestyles, EMFs, and widespread toxins—can lead to harmful epigenetic modifications that...
Archived Case Studies and Featured Content
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major Cardiology...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide it produces to...
Fluoxetine During Development Damaged Hearing and the Brainstem
Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory Brain and Left the...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
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Featured News
Fluoxetine During Development Damaged Hearing and the Brainstem
Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory Brain and Left the...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
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