JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
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Table of Contents | 2021
Childhood Kidney Disease: A Comprehensive Approach Holds Promise
JENNA HENDERSON, ND Abstract Nephrotic syndrome is a challenging and often relapsing kidney condition in children, with Minimal Change Nephrotic Syndrome (MCNS) being the most common form. While conventional steroid therapy remains the standard of care, many cases...
Eating Disorders: Recognizing the Signs in Preteens & Teens
LISA GHENT, ND A lot has changed since I was a kid. The rapid development of technology has introduced smart phones, gaming systems, and tablets, all of which seem to be ubiquitous, and kids are getting hooked on electronics younger and younger. With smart...
The ECS in Childhood Diseases
JAKE F. FELICE, ND, LMP Mention of the endocannabinoid system (ECS) often brings to mind cannabis and its major constituent, tetrahydrocannabinol (THC), which binds the cannabinoid-1 (CB1) receptor. These receptors...
Neuronal Hyperexcitability in PKD: Treatment Using Parenteral Therapy
2021 Student Scholarship – Second Place Case Study MATTHEW RENSHAW RUDDELL, ND LESLIE FULLER, ND Paroxysmal kinesigenic dyskinesia (PKD) is the most common paroxysmal movement disorder and is characterized by episodes of involuntary movements that are...
Amyotrophic Lateral Sclerosis: Microbiome Alterations
SAMANTHA PRYOR, ND Since this is my first article submission to NDNR, I would like to take a moment to tell you a little about myself. As I write this, I am currently employed as the last resident of the University of Bridgeport School...
Roberts’ Formula: A Natural Remedy for IBD & Gastric Ulcers
COLEEN MURPHY, ND, LAC Roberts’ Formula is a traditional naturopathic remedy with a long history of use for common digestive disorders. This abstract examines the origins of Roberts’ Formula, and how naturopathic luminaries like Dr Bastyr used and adapted...
Peripheral Neuropathy: Taking the Edge Off
CHRIS D. MELETIS, ND Neuropathy is a painful condition characterized by numbness, prickling, burning, or other pain sensations, usually in the legs, feet, and hands. Two of the most common forms of neuropathy are diabetic peripheral neuropathy and...
Rotator Cuff Calcific Tendinitis: A Case of US-Guided Single Needle Aspiration & Lavage
SERENA RUSSUM TERRANCE MANNING II, ND, RMSK A 44-year-old female presented via telemedicine with new-onset right shoulder pain. Her pain followed no obvious inciting event, and it had progressively worsened over...
The Importance of Gut Health- Part 4
JAMES SENSENIG, ND Treatments for GI Imbalances Reduce Stress, Improve Lifestyle The most obvious ways to correct gut problems are looking at how and when we eat, reducing stress, changing our lifestyle by slowing...
A Case of MS & Chronic Migraines: Treatment Using LDN & the Wahls Protocol
2021 Student Scholarship – First Place Case Study HEIDI CODINO ANGELA HARDIN, ND Multiple sclerosis (MS) is the most common demyelinating, chronic, inflammatory disease of the central nervous system (CNS).1 MS courses of disease are either...
Hashimoto’s Thyroiditis: The Impact of Nutrition
2021 Student Scholarship – Third Place Case Study PRINCESS BURNETT JENNIFER GREEN, ND Hashimoto’s thyroiditis is an inflammatory autoimmune disease in which the immune system forms antibodies to thyroid peroxidase and...
Stop and Smell the Rosemary: You Might Remember More
LILLEA HARTWELL, ND, RH (AHG) The following article is a monograph outlining the basics of Rosmarini aetheroleum essential oil (EO). The definition, synonyms, selected vernacular names, and geographical distribution of Rosmarinus...
The ECS at the Synapse
JAKE F. FELICE, ND, LMP This article discusses a newly discovered apoptogenic feature of the endocannabinoid system (ECS), known as retrograde transmission. It also discusses important influences of the ECS on neural plasticity, as well...
Migraine & the Microbiome
JESSICA BRANDES, ND According to the Migraine Research Foundation, 18% of women, 6% of men, and 10% of children in the United States experience migraines, resulting in 70% higher healthcare costs for families with a migraine sufferer than for non-migraine-affected...
Archived Case Studies and Featured Content
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...
AANP and AANMC Urge Naturopathic Community to Act: Proposed Federal Rule Threatens ND Student Loan Access and Future Workforce
Washington, DC — The American Association of Naturopathic Physicians (AANP) and the Association of Accredited Naturopathic Medical Colleges (AANMC) are calling on naturopathic physicians, students, patients, and all allies to urgently submit public comments opposing a...
Physician’s Choice Awards and Summit – Interview with Joah Santos
Physician's Choice Awards and Summit – Interview with Joah Santos Host: Razi BerryGuest: Joah Santos (Expert on Tribalism, Marketing Strategist for Fortune 500s, NGOs, and Governments) In this episode, Razi Berry sits down with Joah Santos, a renowned expert on...
The Night Sky Changed Emotional State in 2.5 Minutes
Night sky photos activated all 6 dimensions of awe, increased positive emotion, and restored mental focus in under 3 minutes. People Who Looked at the Night Sky Felt Vastly Different Within Minutes Photographs of deep space and starry night skies activated all 6...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
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FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
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