JAMES SENSENIG, ND LETITIA DICK-KRONENBERG, ND, VNMI This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy...
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Table of Contents | 2022
The Gut-Kidney Axis: A Missing Link in the Treatment of the Kidney Patient
QUINN RIVET, ND Dedicated to my father – Hugh Edmond Rivet Evolving data over the last 40 years confirm that uremic metabolites generated by a dysbiotic microbiome impair kidney function and establish a bidirectional relationship between the gut and...
Don’t Die Dieting: Minimizing the Risks of Weight Loss
CHRIS D. MELETIS, ND Weight loss, when indicated, has always been an integral part of metabolic health and a viable defense against cardiovascular disease and diabetes. However, the COVID-era awareness of morbidity and related mortality has brought a...
Intestinal Permeability: Remove, Repair, Resolve
MICHELLE MADDUX, ND Abstract Intestinal permeability (IP), commonly known as “leaky gut,” results from disruption of the gut’s physical and chemical barriers, allowing translocation of antigens and microbes into systemic circulation. IP has been linked to...
Notes from the Field: July, 2021
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
High-Quality Water: Revitalizing the Source
CHERYL KASDORF, ND The human body requires water to function properly. However, not all water is equivalent. Having high-quality water is essential to human health. But how do we define quality? Water sources in Nature vary...
Eosinophilic Gastroenteritis: How Naturopathic Physicians Can Help
ANDREA GRUSZECKI, ND Eosinophilic gastrointestinal disorders (EGIDs) are a relatively recently described cluster of conditions that can often go overlooked. EGIDs are likely underdiagnosed and rarely recognized,...
Archived Case Studies and Featured Content
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
Akkermansia muciniphila: Clinical Insights on a Next-Generation Probiotic
Sara Love, ND A clinician’s guide to when—and when not—to use A. muciniphila: evidence for gut-barrier support, metabolic and immune effects, pasteurized vs live formulations, and patient selection. Abstract Akkermansia muciniphila is an emerging “next-generation”...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
Clinical Commentary: Climate Change, Tick-borne Illness, and the Shifting Landscape of Clinical Practice
Lynn Klassen, ND Carolyn Mukai, ND Rising temperatures and changing habitats are driving the spread of Lyme disease and co-infections into new regions—challenging outdated risk maps, diagnostic tools, and clinical assumptions. Abstract Climate change is expanding the...
Restoring Cellular Integrity: Phospholipid Therapy as a Key Treatment of Refractory Tick-Borne Disease
Melanie Stein, ND A clinical case highlights how intravenous phosphatidylcholine and targeted membrane repair strategies supported lasting recovery in a patient with refractory Lyme and co-infections. Abstract This case describes a 47-year-old female high school...
Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Chris D. Meletis, N.D. Abstract Long COVID and chronic fatigue syndrome (CFS) share overlapping pathophysiological mechanisms, with mitochondrial dysfunction emerging as a central driver of persistent fatigue, cognitive impairment, and multisystem dysregulation....
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Featured News
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Naturopathic Doctor Continues Walk Across USA for Health Equity
Fargo, ND - Dennis Godby, 69, ND, MA, a Sacramento, CA-Licensed Naturopathic Doctor (ND), to raise awareness across the USA of significant health disparities, and support the “Health Equity,” movement, will continue his inspiring 756 mile walking trek across America...
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