By Devin Miles, ND and Elizabeth Sutherland, ND Emerging research highlights TUDCA’s potential to reduce neuroinflammation, prevent cell death, and mitigate the effects of metabolic dysfunction in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and...
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Table of Contents | 2025
The Breath of Life: Mastering the Art of Conscious Breathing
Jennifer Ruthensteiner, ND Breath sustains life, yet in today’s fast-paced world, it often becomes a neglected tool. Ancient traditions revered breath as the essence of life, linking body, mind, and spirit. Modern life, however, fosters shallow breathing patterns that...
Healing the Gut to Calm the Mind: A Case Study in Pediatric Anxiety and OCD-Like Behavior
Alexander Arrington, ND A 7-year-old male experienced complete remission of severe anxiety and obsessive-compulsive behaviors following targeted microbiome and nutritional therapy. Abstract A 7-year-old male presented with sudden-onset severe anxiety and...
The Mind-Body Bridge: Naturopathic Philosophy Meets Psychotherapy & Neuroscience
Alina Soto, ND, LMHCA “The mind as an emergent property of the body and relationships is created within internal neurophysiological processes and relational experiences. In other words, the mind is a process that emerges from the distributed nervous system extending...
The Link Between Leaky Gut, Food Sensitivities, and Anxiety
Discover how leaky gut and common food sensitivities like gluten and dairy contribute to anxiety by triggering inflammation and disrupting the gut-brain axis. Tiffany Jackson, ND Abstract Leaky gut—characterized by increased intestinal permeability—emerges as a key...
Mental Health’s Flat Earth: Why It’s Time to Abandon the DSM and Face the Illusion of Diagnosis
Steven Rondeau BCN (EEG), qEEG-DL The DSM offers outdated labels based on symptoms, not biology. qEEG and brain mapping provide objective insights that empower more accurate, personalized mental health care. Diagnosing in the Dark: The Problem Psychiatry Refuses...
Ketamine-Assisted Psychotherapy: History, Clinical Uses, and Case Example
Conor Watters, ND, MSAS, PATP From battlefield anesthesia to mental health treatment, ketamine has evolved into a powerful therapeutic tool. Explore its origins, modern psychiatric applications, and a detailed case study demonstrating its potential in...
Sleeping Well During Dynamic Societal Change
How to Protect Sleep Health Amid Political, Economic, and Social Upheaval Catherine Darley, ND Periods of major government and societal change often trigger widespread uncertainty, leading to a rise in sleep complaints. Many clinicians are seeing this firsthand among...
Anticipatory Anxiety: A Case Study in Individualized Homeopathic Care
Michael Knapp, ND, DHANP A compelling case of chronic anxiety, compulsive behavior, and digestive distress resolved through precise homeopathic prescribing guided by pattern recognition and physical symptom correlation. Abstract A 25-year-old male with lifelong...
June 2025 Cont. References
Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...
A Root-Cause Approach to Menopausal Insomnia and Brain Dysfunction: A Case Study
Discover how a 48-year-old woman overcame chronic insomnia, fatigue, and cognitive decline during menopause through a personalized, brain-first, hormone-balancing approach. Stephanie Yang, ND Abstract Menopause is not only a hormonal milestone but also a neurological...
Seeing Beyond the Mirror: How Psilocybin Could Transform Body Dysmorphic Disorder Treatment
Georgiana Cullen-Kerney, ND, LAc Emerging research reveals that psilocybin, the active compound in magic mushrooms, may offer a groundbreaking approach to treating Body Dysmorphic Disorder (BDD) by enhancing cognitive flexibility and reducing obsessive thought...
Nighttime Urination and Sleep Apnea: The Overlooked Connection
Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...
Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Resolving Acne Vulgaris Through Gut and Hormone Support: A Case Study
By Chelsea Smithback, ND Introduction Acne vulgaris is a very common skin condition, with a prevalence rate ranging from 25% to 95% among adolescents. It is more common in males than females. Acne can persist into adulthood or have a delayed onset during this stage of...
Archived Case Studies and Featured Content
D Laura Chan Discusses The Fertility Factor No One Talks About: Men’s Energetic Health
Emma Pollon McLeod The importance of Communication between Naturopathic Doctors and Pharmacist
Pamela Frank Micronutrient Deficiencies and Glucose Dysregulation
Lara Briden A Troubleshooting Approach to Insulin Resistance
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract This...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
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Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
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