Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
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We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
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Featured Article | Fertility
Infertility Case Study: It’s Usually Never Just 1 Thing
Tolle Totum Reena Singh, ND Infertility affects 1 out of 8 couples1 and can be a sign of other imbalances and deficiencies in the body. When HG presented to my office, she was a 38-year-old woman who had been trying to get pregnant for 12 years. She had already...
Exclusive Content | Fertility
Same Symptoms, New Remedy?
Joseph Kellerstein, DC, ND James is a 47-year-old workaholic. He is dark haired and of pale complexion and quite chilly. Recently there has been a lot rolling his way in terms of business and financial reversal. Far from receiving all of this in good humor, he has...
Naturopathic Approach to HSV Infections
David Hogg, ND I find herpes simplex virus (HSV) infections one of the most easily treated infectious diseases. Although I’ll be focusing on genital herpes in this article, the same treatment guidelines follow for oral herpes, herpes zoster and post-herpetic...
Diagnosing Andropause: Vague and Varying Symptoms can Result in Difficult Assessment
Bronner Handwerger, ND By the time men are between the ages of 40 and 55, they can experience a phenomenon similar to female menopause, called andropause. Unlike women, men do not have a clear-cut indication, such as the cessation of menstruation, to mark this...
Sunscreen, Vitamin D and Cancer
Jacob Schor, ND Summer is here, and the sunscreen displays in local retail stores have popped up like mushrooms after a week of rain. There is little doubt that using these topical sunscreens prevent sunburn, but little convincing evidence argues that they prevent...
Premature Ovarian Failure: Diagnosis Within the Autoimmune Realm
Arlene Donar, ND Two female patients, 21 and 24 years old, recently presented to my office with idiopathic long-term cessation of menses. Secondary amenorrhea ranged from 15 months in the 21-year-old to 3+ years in the 24-year-old. Menopausal symptoms such as vaginal...
Aconite: A Powerful Tool, or an Agent to Avoid?
Eric Yarnell, ND, RH(AHG) Though various species of aconite have been considered important medicinal plants by most traditions in areas where it grows, it has become a feared agent to avoid in much of the West. This is unfortunate, because in appropriate doses aconite...
Chronic Lead Exposure, Women and Hypertension
Mitch Kennedy, ND It is common knowledge that bone turnover accelerates as women enter perimenopause and menopausal years. What is not commonly known is that this turnover also accelerates the release of heavy metals, particularly lead, stored in the bones. As lead is...
Pediatric Probiotics: Impact on the Development of a Normal Immune System
Mary Grabowska, ND, LM, LAc and Mairi R. Ross Probiotics are familiar to most naturopathic physicians in their pediatric practice as a way of supporting the restoration of natural flora during and after antibiotic use. As a naturopathic midwife, I use probiotics in...
Archived Case Studies and Featured Content
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
Skin-to-Skin Contact: Science Validates Traditional Wisdom
Maternal Instinct is Rooted in Biology and Expressed Through Culture Throughout history, maternal instinct has consistently highlighted the need for mothers to maintain physical closeness with their newborns. Cultural traditions globally, from China's "zuo yuezi" to...
Anacyclus Pyrethrum in Parkinson’s Disease: A Clinical Exploration of Cognitive Decline
Parkinson’s disease (PD) is often described primarily as a movement disorder, but this definition captures only a fraction of its complexity. The familiar symptoms, tremors, stiffness, and slow movements, are outward signs of a more profound neurological disruption...
Topical Treatments for Rosacea: A Clinical Comparison of Efficacy and Patient Outcomes
Jordan Robertson, ND A detailed evaluation of the most commonly prescribed topical treatments for rosacea, comparing efficacy, patient suitability, and clinical outcomes. Rosacea significantly affects patients' quality of life, and evidence indicates that any...
Mental Health & Insomnia – May 2025 | Volume 20 | Issue 5
Issue Details Volume 20 | Issue No.05Published: May 2025Theme: Mental Health and InsomniaISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=xbnZ815tnZmF3SIlTBBI6f&source=wordpress" width="100%" height="637"]
Physical Punishment Harms Children’s Physical and Neurological Health
Neuroscience Reveals Lasting Damage from Physical Discipline A Comprehensive 2025 Meta-Analysis Reveals Physical Punishment Activates Toxic Stress, Causes Structural Brain Damage, and Leads to Emotional and Behavioral Dysfunction Pain as a Protective Biological Signal...
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
Influenza and COVID Vaccines Disrupt Hypothalamic-Pituitary Axis
Vaccine Immune Response Interferes with Female Reproductive Cycle 2025 JAMA Study Reveals Direct Evidence of Neuroendocrine Effects The 2025 study published in JAMA Network Open provides clear evidence that vaccines affect brain regulatory systems. Researchers...
Midlife Movement Determines Brain Aging
Midlife is the time to move more to protect your brain. By your 40s and 50s, measurable changes in brain structure have already begun. Gray matter volume starts to decline. White matter pathways lose integrity. Amyloid plaques, protein deposits linked to Alzheimer’s...
The Integrative Management of Psoriasis
A Case Study in Homeopathy, Nutrition, and Lifestyle Medicine A comprehensive, patient-centered approach to managing psoriasis by addressing root causes through homeopathy, gut health, and metabolic balance. By Marisa Kassimir, ND Introduction and Case Presentation...
Plastic Chemical Exposure Linked to Over 356,000 Cardiovascular Deaths in 2018
DEHP in Plastics Promotes Inflammation and Arterial Damage Leading to Heart Disease Millions handle plastic products daily, including food containers, medical tubing, and water bottles. These common items often contain di-2-ethylhexyl phthalate (DEHP), a chemical used...
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
Influenza and COVID Vaccines Disrupt Hypothalamic-Pituitary Axis
Vaccine Immune Response Interferes with Female Reproductive Cycle 2025 JAMA Study Reveals Direct Evidence of Neuroendocrine Effects The 2025 study published in JAMA Network Open provides clear evidence that vaccines affect brain regulatory systems. Researchers...
Midlife Movement Determines Brain Aging
Midlife is the time to move more to protect your brain. By your 40s and 50s, measurable changes in brain structure have already begun. Gray matter volume starts to decline. White matter pathways lose integrity. Amyloid plaques, protein deposits linked to Alzheimer’s...
The Integrative Management of Psoriasis
A Case Study in Homeopathy, Nutrition, and Lifestyle Medicine A comprehensive, patient-centered approach to managing psoriasis by addressing root causes through homeopathy, gut health, and metabolic balance. By Marisa Kassimir, ND Introduction and Case Presentation...
Plastic Chemical Exposure Linked to Over 356,000 Cardiovascular Deaths in 2018
DEHP in Plastics Promotes Inflammation and Arterial Damage Leading to Heart Disease Millions handle plastic products daily, including food containers, medical tubing, and water bottles. These common items often contain di-2-ethylhexyl phthalate (DEHP), a chemical used...
Optimizing Healthy Aging for Older Adults
Insights from a Case Series Using a Novel Supplement Regimen Jen Palmer, ND; Joseph M. Keenan, MD Dietary supplements can provide older adults a therapeutic option for maintaining optimal health without relying on prescription drugs. This article summarizes key...
Selective Toxicity of Vitamin C to Cancer Cells
A vital aspect of high-dose vitamin C therapy is its selective toxicity towards cancer cells. Cancer cells are uniquely susceptible due to their inherently higher levels of oxidative stress and reactive iron. At therapeutic concentrations, intravenous vitamin C...
Gut Bacteria Directly Trigger Chronic Pain in Fibromyalgia
Gut microbes from patients rapidly activate immune responses and nerve changes that drive lasting, unexplained pain. Gut Microbes Influence Chronic Pain and Immunity Fibromyalgia is a chronic pain condition characterized by widespread pain throughout the body, often...
Healthy Gut, Healthy Blood: Gut Health Shown to Prevent Leukemia
Naturopathic medicine has long emphasized digestive health as foundational to robust immune function. Early naturopathic physicians drew inspiration from pioneering microbiologist Elie Metchnikoff, who proposed in the early 1900s that beneficial gut bacteria are...
Air and Light Pollution Raise Childhood Thyroid Cancer Risk by 7–25%
Early-Life Exposure from Pregnancy to Age One Impacts Teens' Health Early exposure to air pollution and artificial electric lighting increases children's thyroid cancer risk by measurable amounts. Children exposed from pregnancy through their first year experience a...
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Featured News
Midlife Movement Determines Brain Aging
Midlife is the time to move more to protect your brain. By your 40s and 50s, measurable changes in brain structure have already begun. Gray matter volume starts to decline. White matter pathways lose integrity. Amyloid plaques, protein deposits linked to Alzheimer’s...
Plastic Chemical Exposure Linked to Over 356,000 Cardiovascular Deaths in 2018
DEHP in Plastics Promotes Inflammation and Arterial Damage Leading to Heart Disease Millions handle plastic products daily, including food containers, medical tubing, and water bottles. These common items often contain di-2-ethylhexyl phthalate (DEHP), a chemical used...









