An in-depth exploration of how somatic awareness, interoception, and relational neuroscience can support nervous system regulation, authenticity, and healing in clinical practice. Allison Creech, M.Ed., ND Abstract This article examines mind-body medicine as a...
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Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Dr. Nicole Roberts, ND Abstract In this case report, we see a 48-year-old female, over...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Dr. Leslie Solomonian, ND Abstract This article examines rising...
Borage (Borago officinalis): Botanical Ally for Courage, Self-Expression, and the Restoration of Self-Love
An integrative exploration of borage’s traditional uses, phytochemistry, and clinical applications in supporting self-compassion, stress resilience, and emotional regulation in naturopathic practice. Dr. Katelyn Mudry, ND, MSc Introduction Over the past year,...
Lavender Essential Oil and Anxiety Management: A Case Study
A case-based examination of oral lavender essential oil as a non-pharmaceutical intervention for generalized anxiety disorder in a patient seeking evidence-informed, integrative care. Dr. Jennifer Brusewitz ND Abstract This case study explores the use of a...
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Featured Article | Fertility
Metformin & Myo-inositol: Management of Insulin Resistance in Women with PCOS
LIQAA ESSAM NASER, ND, MBCHB, CCT KRIS SOMOL, ND Student Scholarship – Second Place Research Review Abstract Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder frequently characterized by insulin resistance...
Exclusive Content | Fertility
A Surprising Menopause Case Study, Part 2
Tolle Totum Deborah McKay, ND In Part 1 of this case study, published in December 2019, I wrote about a 50-year-old woman who presented in January 2019 with a laundry list of health complaints. Some were chronic, such as recurrent sinus infections, GI disturbances,...
Adrenal Fatigue: Environmentally Induced Adrenal Hypofunction?
Tolle Causam Andrea Gruszecki, ND Normal adrenal gland function is essential during acute and chronic stress responses.1 Although commonly used, the term “adrenal fatigue” is not considered a diagnosable illness by allopathic medicine, perhaps because the effects of...
Love & Male Factor Infertility: What’s Oxytocin Got to Do with It?
Tolle Totum Breanna M. Guan, ND Oxytocin has rightly claimed its name as the hormone of love, with its essential role in birth, bonding, milk production, and feeding. We now know how important oxytocin is for social and emotional development in newborns and children...
Prolozone
Regenerative Medicine Fred G. Arnold, DC, NMD Prolozone therapy shall be the second in our series of discussions about regenerative joint injection procedures. Prolozone is another misunderstood and often-overlooked treatment for painful musculoskeletal...
How to Make a Living: Naturopathic Grads Have a Decision to Make
Education David J. Schleich, PhD At the end of a long day at a recent conference, a half-dozen new naturopathic doctors, just recovering from NPLEX, were looking for advice. They sought perspective on what it takes, business-wise, to succeed out of the gate in...
Biopharma & Biomedicine: The Stacked Deck
Education David J. Schleich, PhD The monolith that is the biomedicine industrial complex in America costs hit 18.2% in 2018, regardless of the irrefutable data about growing chronicity and the poor health of young people and boomers alike. (Statistics Portal, 2019)...
Rosa canina: A Potential Herbal Preventive for Post-C-section UTI
Tolle Causam Kris Somol, ND Mary Schroeder, BSC Kathryn Hightower, BA Francisco Miranda, BSC Urinary tract infection (UTI) is a common ailment in female-bodied individuals. Certain populations are at an increased risk for UTI, including, but not limited to, pregnant...
Preconception Planning: Enhancing Healthier Baby Outcomes
Naturopathic Perspective Shannon Sinsheimer, ND Preconception planning is often recommended to couples who have an interest in optimizing their fertility, conception, pregnancy, baby’s development, and lifelong health and wellness of their children. However, not all...
Archived Case Studies and Featured Content
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide it produces to...
Fluoxetine During Development Damaged Hearing and the Brainstem
Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory Brain and Left the...
Eight Communities You Never Thought of That Can Be a Goldmine for Finding New Patients
Advancing Public Health Through Community Alignment Valuing self-reliance and freedom, certain enthusiast groups are naturally drawn to holistic, naturopathic, and integrative care because it aligns with their ethos of personal autonomy and preparedness. These are...
Overcoming Objections to Pay Cash for Doctor’s Visits: Scripts Your Staff Can Use
Razi Berry Handling Objections Handling objections to paying cash for doctor’s visits can be a delicate task. It requires empathy, clear communication, and an understanding of the patient's concerns. Here are some effective scripts that your staff can use to address...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Custom Publishing
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Featured News
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major Cardiology...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....














