A comprehensive scoping review explores how olive oil and its bioactive constituents may influence depression, anxiety, stress, and other mental health outcomes across clinical trials, epidemiological research, and preclinical models. Dr. Monique Aucoin ND MSc Vanessa...
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Right now, someone in your community is Googling "how to get off antidepressants safely."They're not alone. Searches for "antidepressant withdrawal" are up 200%. In Canada, taper-related searches have increased 160 to 180% over the last few years.They're...
New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes
Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery. A...
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Microplastics and Nanoplastics: Emerging Health Risks and Clinical Implications
Frasier Smith, ND Abstract Understanding how persistent plastic particles infiltrate human physiology—and what clinicians can do to help patients mitigate exposure and health impacts. Micro- and nanoplastic exposure is now ubiquitous, with growing evidence linking...
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Featured Article | Fertility
Preserving Female Fertility: Key Diet and Lifestyle Factors for Maintaining Reproductive Health
Student Scholarship – First Place Research Review DAIANA CASTLEMAN, HBSC STEFANIE TROWELL, ND Women today are increasingly aware of the impact age has on their fertility. Armed with the knowledge that female fecundity begins to decrease after...
Exclusive Content | Fertility
GMO Crops & Glyphosate: Detrimental Effects on Health
Docere Humaira Quraishi, ND, MS An historic event took place in August of 2018 when Dewayne Johnson won his lawsuit against Monsanto; he was granted “$39.2 million in compensatory damages and $250 million in punitive damages.”1 Johnson, a 46-year-old gardener,...
Antioxidants & Male Infertility: Can Supplements Make a Difference?
Tolle Causam Chris D. Meletis, ND Modern couples are attempting to procreate in a world of toxins and dietary and lifestyle habits that produce an overabundance of reactive oxygen species (ROS); antioxidant defenses are burdened as a result. Toxins (eg, bisphenol-A...
Estrogen Dominance: When an Unhealthy Gut Estrobolome is to Blame
Naturopathic Perspective Carrie Jones, ND, MPH It is well established that elevated estrogen can pose many problems for both men and women. Not only can it result in estrogen dominance symptoms; if not properly detoxified, it increases the risk of several cancers....
Estrogen Dominance in Women
Tolle Totum Serena Goldstein, ND Young girls today are developing breasts and starting their periods earlier than in previous generations. High estrogen levels are a likely key contributor to this premature development in girls. Excess estrogen over time places women...
Antioxidants for Female Infertility: A Review of the Literature
Erica Nikiforuk, BSc, ND, RAc Tolle Causam Infertility, defined as trying to conceive for over 1 year with no success,1 affects as many as 16% of Canadian couples.2 While the cause of infertility is not always identified, it is important to assess for both female and...
The Fourth Trimester
Molly Jarchow, ND, LM Naturopathic Perspective Around the world, the Fourth Trimester has been acknowledged as a special time for both mom and baby that requires extra care and attention. Most often, the Fourth Trimester has been defined as the first 3 months after...
Ovarian Factor Infertility: Workup & Natural Medicine Approach
Corina Dunlap, ND, MS Tolle Causam One of the hardest and most important aspects of supporting individuals and couples with infertility is correct identification and diagnosis of all potential causes (“factors”). Most infertility factors fall into the categories of...
Preparing for Pregnancy Self Care and Epigenetic Potential
Allison Creech, MEd, ND Vis Medicatrix Naturae Many women seek naturopathic support for hormone balance as a first step toward a future pregnancy. The desire for pregnancy can motivate a woman to engage in new behaviors, such as seeing a naturopath for the first...
Archived Case Studies and Featured Content
Fifteen Questions to Get Patient Commitment
Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and what integrative care can do about it. This article explores the shared metabolic, inflammatory, and microbiome-driven pathways linking...
Arterial Plaque Regression: A Case-Based, Integrative Approach to Cardiovascular Risk Reduction
A preventive cardiology case demonstrates how advanced imaging, aggressive lipid optimization, and integrative therapies can reduce coronary plaque burden in a high-risk patient. Dr. Stephen Parcell, ND This case report examines the regression of coronary artery...
Resolution of Exercise-Induced Asthma with Individualized Homeopathic Treatment: A Case Report
A case demonstrating sustained remission of exercise-induced asthma, allergic oropharyngeal symptoms, and recurrent respiratory infections in an adolescent following constitutional homeopathic care. This case report describes the resolution of exercise-induced asthma,...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
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Featured News
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide it produces to...
Fluoxetine During Development Damaged Hearing and the Brainstem
Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory Brain and Left the...











