Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
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The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
Clinical Commentary: Climate Change, Tick-borne Illness, and the Shifting Landscape of Clinical Practice
Lynn Klassen, ND Carolyn Mukai, ND Rising temperatures and changing habitats are driving the spread of Lyme disease and co-infections into new regions—challenging outdated risk maps, diagnostic tools, and clinical assumptions. Abstract Climate change is expanding the...
Restoring Cellular Integrity: Phospholipid Therapy as a Key Treatment of Refractory Tick-Borne Disease
Melanie Stein, ND A clinical case highlights how intravenous phosphatidylcholine and targeted membrane repair strategies supported lasting recovery in a patient with refractory Lyme and co-infections. Abstract This case describes a 47-year-old female high school...
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Featured Article | NDNR Issues
Mind-Body Medicine for Empaths: A Case Study of Hives
Nikita Patel Empaths differ from empathetic individuals. People with empathy show compassion for those suffering without taking on that suffering themselves. Then there are empaths, who not only feel the pain of others but internalize it as their own. Empaths possess...
Exclusive Content | NDNR Issues
August 2005 | Autoimmune
Treating Autoimmune Disease Using Naturopathic Principles.........................cover Leslie Axelrod, ND, LAc Clinical Rounds in Functional and Nutritional Medicine: Fatigue: Functional Hypothyroidism..........................>> bottom of cover David M. Brady,...
Archived Case Studies and Featured Content
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New CDC Report Shows Autism at Highest Rate Ever Recorded
Autism prevalence among U.S. children has reached a new high, according to a CDC report released in April 2025. New CDC data released April 2025 show that 1 in 31 eight-year-olds had received an autism diagnosis by 2022, a 22% increase in just two years. At some...
Fermented Cabbage Reduces Gut Lining Damage by 40%
Whole Fermented Vegetables Preserve Intestinal Barrier Where Supplements Fall Short Preserved tight junction integrity and reduced gut lining damage by 40% under inflammatory stress Prevented the translocation of harmful compounds across the intestinal barrier...
Chronic Pain Predicts Depression Through Systemic Inflammation and Neural Disruption
Inflammatory and Neural Pathways Explain Depression in Patients with Physical Pain Pain is not merely a secondary symptom of illness. It is an indicator of unresolved physiological disruption. Inflammation, far from being a defect, is the body’s coordinated response...
Nanoplastics Found in Blood and Fluids Using New Laser-Based Detection Tool
Chemical Profiling of Plastic Particles Reveals Implant Risks and Long-Term Exposure Concerns Nanoplastics are synthetic polymer fragments smaller than 100 nanometers. Microplastics range in size from 100 nanometers to 5 millimeters. By comparison, a human red blood...
Mediterranean Diet and Movement Preserve Bone Density in Older Women
Structured Weight Loss Protects Lumbar and Hip Bone Density in Postmenopausal Women Older women with overweight or obesity who followed a calorie-controlled Mediterranean diet combined with regular physical activity maintained key markers of bone health over three...
Mitochondrial Disruption Explains Systemic Benzodiazepine Side Effects
New Evidence Links Long-Term Use and Withdrawal Symptoms to Cellular Energy Dysfunction Benzodiazepines impair mitochondrial signaling across multiple systems in the body, not just GABA receptors in the brain. Mitochondria play a central role in regulating cell energy...
Paternal Depression Increases ADHD and Behavioral Risk by 37%
Depressed Fathers Raise Behavioral and Social Risk in School-Aged Children Children whose fathers had depression at age 5 were up to 37% more likely to develop hyperactivity, oppositional behaviors, and ADHD symptoms by age 9, based on teacher reports. These children...
Therapeutic Order: Navigating an Ever-Increasing Toxic World
Healing Chronic Illness through Environmental Medicine By Kim Furtado, N.D. Exposure to heavy metals, persistent organic pollutants, and other chemicals is rising, with no clear end in sight. The identification of novel forever chemicals, contamination of everyday...
Allergies, Asthma & Eczema: Pediatric Treatment of the Atopic Triad
Autumn Frandsen, ND Abstract The atopic triad—eczema, asthma, and allergies—frequently presents early in pediatric patients and often shares overlapping immune dysfunction and environmental triggers. In this clinical review, Dr. Autumn Frandsen explores the...
Inflammation During Pregnancy Alters Brain Development: A Groundbreaking Study
Inflammatory Response During Pregnancy Creates Permanent Brain Structure Changes Inflammation during pregnancy reduces vital brain immune cells by 70% in developing babies, creating permanent changes to brain structure visible on MRI scans. This groundbreaking finding...
Mitochondrial Disruption Explains Systemic Benzodiazepine Side Effects
New Evidence Links Long-Term Use and Withdrawal Symptoms to Cellular Energy Dysfunction Benzodiazepines impair mitochondrial signaling across multiple systems in the body, not just GABA receptors in the brain. Mitochondria play a central role in regulating cell energy...
Paternal Depression Increases ADHD and Behavioral Risk by 37%
Depressed Fathers Raise Behavioral and Social Risk in School-Aged Children Children whose fathers had depression at age 5 were up to 37% more likely to develop hyperactivity, oppositional behaviors, and ADHD symptoms by age 9, based on teacher reports. These children...
Therapeutic Order: Navigating an Ever-Increasing Toxic World
Healing Chronic Illness through Environmental Medicine By Kim Furtado, N.D. Exposure to heavy metals, persistent organic pollutants, and other chemicals is rising, with no clear end in sight. The identification of novel forever chemicals, contamination of everyday...
Allergies, Asthma & Eczema: Pediatric Treatment of the Atopic Triad
Autumn Frandsen, ND Abstract The atopic triad—eczema, asthma, and allergies—frequently presents early in pediatric patients and often shares overlapping immune dysfunction and environmental triggers. In this clinical review, Dr. Autumn Frandsen explores the...
Inflammation During Pregnancy Alters Brain Development: A Groundbreaking Study
Inflammatory Response During Pregnancy Creates Permanent Brain Structure Changes Inflammation during pregnancy reduces vital brain immune cells by 70% in developing babies, creating permanent changes to brain structure visible on MRI scans. This groundbreaking finding...
New Study Links Smartphone Attention to Reduced Body Awareness
Research finds smartphone stimuli trigger heart rate changes and diminish the ability to sense internal bodily signals A recent study published in Communications Psychology has uncovered concerning links between smartphones and our internal bodily awareness. Our...
Homeopathic Case Study: Treating PANDAS with Tarentula Hispanica
A Case Study on Pediatric Autoimmune Neuropsychiatric Disorder Associated with Strep (PANDAS) Successfully Managed with Homeopathy By Jennifer Bahr, ND, DHANP, FMAPS Background Summary & Initial Case History: LW was an 8-year-old female who presented to my...
Traditional Chinese Medicine Formulas Shorten COVID Recovery and Lower Severe Case Risk
Three traditional formulas improve chest symptoms, fatigue, and cough duration in COVID-19 patients In 57 clinical trials, traditional Chinese medicine (TCM) reduced fever duration by up to 2.2 days, accelerated viral clearance, and improved lung recovery on chest CT...
Inflammation During Pregnancy Permanently Rewires the Brain
Lifelong Cognitive Health Begins in the Womb With Immune-Driven Brain Changes Inflammation during pregnancy eliminates 70 percent of fetal brain cells responsible for forming critical neural circuits. These changes are visible on MRI scans at birth and are linked to...
Gastrointestinal Disease Costs U.S. $111.8 Billion Annually
GI Health Burden Highlights Urgent Need for Improved Treatment and Research In 2021, gastrointestinal diseases cost the U.S. healthcare system $111.8 billion. Conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) affect millions,...
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Featured News
Healthy Gut, Healthy Blood: Gut Health Shown to Prevent Leukemia
Naturopathic medicine has long emphasized digestive health as foundational to robust immune function. Early naturopathic physicians drew inspiration from pioneering microbiologist Elie Metchnikoff, who proposed in the early 1900s that beneficial gut bacteria are...
Air and Light Pollution Raise Childhood Thyroid Cancer Risk by 7–25%
Early-Life Exposure from Pregnancy to Age One Impacts Teens' Health Early exposure to air pollution and artificial electric lighting increases children's thyroid cancer risk by measurable amounts. Children exposed from pregnancy through their first year experience a...









