Decreased Testosterone in Workers Exposed to Phthalates

2006 | October, Environmental Medicine, Fertility, Men's Health, Women's Health

Mitch Kennedy, ND

Phthalate esters (PE) are used in almost every plastic product on the market today. Each year, 2 to 8 million tons of PE are produced worldwide. Phthalates have been shown to be endocrine-disrupting chemicals associated with testicular and ovarian cancers, birth defects and now possibly male infertility.

While use of these products creates a low-level chronic exposure, the people manufacturing the products are placed at much higher risk due to workplace exposure to phthalates. Researchers in China measured gonadotropin and gonadal hormones in 74 male workers in a poly-vinyl chloride (vinyl) flooring plant, and compared them to an equal number of unexposed construction workers.

Compared to the unexposed workers, the exposed workers had substantial significantly elevated concentrations of phthalates (MBP & MEHP) – (p<0.001.) Testosterone was significantly lower (8.4 vs. 9.7 µg/g creatinine, p=0.019) in exposed workers than in unexposed workers, and declined as phthalate exposure increased in the factory worker group. It is suspected that both fetal and adult exposure to PE contributes to impaired human fertility.

Source: Guowei P. et al: Decreased serum free testosterone in workers exposed to high levels of Di-n-butyl Phthalate (DBP) and Di-2-ethylhexyl Phthalate (DEHP), a cross-sectional study in China, http://dx.doi.org/doi:10.1289/ehp.9016.


Kennedy-HeadshotMitch Kennedy, ND has a family practice in Avon, CT, and is the first ND with clinical privileges at the University of Connecticut, a teaching hospital. Before graduation from Southwest College, Kennedy earned an international reputation as a leader in pollution prevention, showing industries around the world how preventing pollution saves money.

NDNR
Author: NDNR

Current Issue

NDNR Spring 2026 of July issue

Table of Contents

Trending Articles

From PCOS to PMOS: What the Name Change Means for Your Practice

From PCOS to PMOS: What the Name Change Means for Your Practice

Dr. Jaclyn Smeaton, ND   A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...

The Fertility Factor No One Talks About: Men’s Energetic Health

The Fertility Factor No One Talks About: Men’s Energetic Health

Dr. Laura Chan, ND, L.Ac.   While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...

Custom Publishing

Quantum Energy Effects on Cell Recovery Rates

Quantum Energy Effects on Cell Recovery Rates

Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human...

Featured News

The 2026 AzureWellness Summit

The 2026 AzureWellness Summit

Building a Community of Practitioners to Inspire Healthier Families  June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June 22–26,...