UNIVERSITY OF ARIZONA EXPERTS LIST TOP PREVENTABLE BIRTH DEFECTS AS PART OF PREVENTION MONTH EFFORTS

Birth Defects Still Affect Some 160,000 Babies Each Year In The U.S.

[protected]TUCSON, ARIZONA – Experts at the Arizona Pregnancy Riskline, a non-profit based at the University of Arizona College of Pharmacy that aims to educate women about exposures during pregnancy and breastfeeding, report some 160,000 babies are still being affected by birth defects each year in the U.S.

“What we know is that many birth defects are simply beyond our control. However, what’s frustrating is that some of these birth defects are indeed preventable, but many women simply don’t know which measures to take,” said Dee Quinn, founder and director of the Arizona Pregnancy Riskline, and a clinical instructor at the University of Arizona. “I can’t emphasize enough how important it is to educate all women in order to give them the best chances of having a healthy baby,” she added.

In honor of National Birth Defects Prevention Month, which is recognized during January each year, Arizona Pregnancy Riskline counselors are stepping up efforts to help educate the public. Counselors, who provide Arizona women answers to questions about exposures during pregnancy and lactation through a toll-free hotline, (888) 285-3410, have compiled a list of a few of the preventable causes of some of the most common birth defects.

1. Neural Tube Defects and Folic Acid Supplementation

Neural tube defects are malformations of the spinal cord that are serious and can be life-threatening. Two of the most common neural tube defects are spina bifida and anencephaly, and these occur in about 1 in every 1,000 live births. Getting enough folic acid, and following recommendations to take a multivitamin with folic acid or a folic acid supplement containing at least 400 mcg daily during all of the years that a woman is capable of becoming pregnant can prevent up to 70% of these defects. Because the neural tube closes in the first month after conception, a time when many women do not yet realize they are pregnant, it is important for women, in addition to a healthy diet, to be taking supplements before pregnancy. That is why the recommendation is to take supplements throughout the childbearing years.

2. Heart Defects and Maternal Obesity

Heart defects are some of the most common malformations. The various types of errors in the formation of the heart may occur in as many as 1 in 100 live births. Mothers who are obese at the time they become pregnant (Body Mass Index >30) seem to have an increased chance of having a baby with several kinds of birth defects, including heart defects. If mothers can reduce body weight by making healthy lifestyle changes prior to becoming pregnant, this can help prevent heart and other defects in their baby.

3. Fetal Alcohol Syndrome (FAS) and Maternal Drinking

“It’s thought that Fetal Alcohol Syndrome is the most common recognizable environmental cause of mental retardation,” said Quinn, a member of the Arizona Fetal Alcohol Spectrum Disorder Taskforce. Children with Fetal Alcohol Syndrome are born small, have problems with learning and behavior, and may have other birth defects. “It’s completely preventable by avoiding alcohol during pregnancy,” she added. This means that women who have the potential to become pregnant can prevent having a child affected by alcohol by modifying their alcohol drinking habits prior to becoming pregnant. Once a woman knows she is pregnant, she can prevent later effects of alcohol on the baby’s growing brain by avoiding alcohol through the remainder of the pregnancy and during breastfeeding.

“This list is just a start,” said Sara Riordan, genetic counselor at the Arizona Pregnancy Riskline and a clinical instructor in the UA College of Pharmacy. “There are so many things women can do during pregnancy to prevent certain birth defects, such as avoiding cigarettes and illicit drugs. Also, getting early prenatal care to manage of chronic diseases like diabetes and hypertension is crucial. The Arizona Pregnancy Riskline is here to help provide as much information to Arizona women as possible,” she added.

The Arizona Pregnancy Riskline’s national affiliate, The Organization of Teratology Information Specialists (OTIS), has partnered with the National Birth Defects Prevention Network (NBDPN) to provide a complete list of resources to promote Birth Defect Prevention Month that can be found at NBDPN.org. This year’s birth defects awareness campaign theme is “Medication Use Before, During and After Pregnancy.” In addition, OTIS has an extensive list of fact sheets in English and Spanish that includes various medications and their effects during pregnancy and breastfeeding. These can be found at OTISPregnancy.org.

Questions or concerns from women in Arizona about other exposures during pregnancy and breastfeeding can be directed to the Arizona Pregnancy Riskline, at (888) 285-3410. Outside of Arizona, please call the Organization of Teratology Information Specialists at (866) 626-OTIS (6847).

The Arizona Pregnancy Riskline is the Arizona affiliate of OTIS, a North American non-profit dedicated to providing accurate evidence-based, clinical information to patients and health care professionals about exposures during pregnancy and lactation through its toll-free hotline and website, www.OTISPregnancy.org. Nearly 100,000 women seek information about birth defect prevention from OTIS and its affiliates every year.[/protected]