New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes

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Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance

Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery.

A randomized, double-blind, placebo-controlled study evaluated Cortisol Balance in 499 healthy adults seeking support for anxiety and stress. Over six weeks, participants received either Cortisol Balance or a placebo. The supplement, which contains clinically effective levels of ashwagandha, B vitamins, magnesium, boswellia, vegan omega-3, eleuthero extract, and copaiba extract, was assessed using validated measures of anxiety, stress, sleep and mood.

Findings showed that Cortisol Balance led to significant improvements in feelings of anxiety, perceived stress, sleep disturbance, and mood, compared to placebo, among participants who reported moderate levels of anxiousness. In this group, up to 85% of respondents reported improvement in both the levels and frequency of anxiousness and stress.

“This study provides important evidence that a comprehensive, systems-based approach to stress management can help people better adapt to the pressures of daily life,” said John P. Troup, Ph.D., chief science and innovation officer of Blueroot Health, the parent company of Vital Nutrients. “By supporting cortisol balance and healthy adrenal function, we can help the body manage stress where it starts, not just mask the symptoms, and improve overall well-being without relying on single-ingredient solutions.”

Unlike many supplements that draw on isolated ingredient data, Cortisol Balance was evaluated as a finished formula in a large and diverse U.S. population, a notable advancement in supplement research design. The product’s blend of adaptogenic herbs and nutrients works synergistically to help the body recover, reset and rebalance after stress, supporting the hypothalamic-pituitary-adrenal (HPA) axis, endocannabinoid system, and circadian rhythm.

Cortisol Balance is vegan, free of hemp-derived ingredients, and manufactured in Vital Nutrients’ NSF-certified facility in Middletown, Connecticut.

Vital Nutrients was founded in 2000 by healthcare practitioners on a mission to positively impact the health of both people and the planet. The company produces a diverse portfolio of premium quality, clinically relevant, clean-label formulas, trusted and recommended by healthcare practitioners and individuals worldwide. Known for its efficacy-first formulations and rigorous quality assurance, Vital Nutrients has built a long-standing reputation for excellence.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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