A study by Penn State researchers looked at zinc levels in breast milk as an indicator or breast health during lactation. In previous studies, they found that the protein ZnT2 is critical for secreting zinc into breast milk, and women who have mutations in the gene that encodes ZnT2 have substantially lower milk zinc levels, leading to severe zinc deficiency in exclusively breast-fed infants. The researchers further found that getting rid of that protein, significantly altered the milk composition, hampering the efforts to nurse their offspring.
Now the researchers have found that genetic variation resulting in either loss or gain of function may be common in women and in some cases is associated with indicators of poor breast function. That link from abnormally-low zinc levels may help identify those mothers that have poor breast function and, therefore, trouble breast-feeding.
The researchers were surprised the genetic mutation in the protein would be so common. Out of 54 breastfeeding women, 36 percent of them had the mutation in the protein.
“Importantly, among the subjects with ‘normal’ milk (zinc levels), no variants in ZnT2 were detected,” the researchers wrote.
For more information, read the full study.
http://www.sciencedaily.com/releases/2015/12/151222113507.htm
http://link.springer.com/article/10.1007%2Fs10911-015-9338-z
