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Table of Contents | 2018 | January

Questions in the Queue: What our Deans Might Not Know Yet

David J. Schleich, PhD Education At a recent educational leadership conference in New York, one keynoter among 3 that weekend said, "Our faculty and their deans often don't know what they don't know, and that is a really big problem in our time." Robust applause...

Probiotics in IBS

Keegan Sheridan, ND Docere Irritable bowel syndrome (IBS) is a functional disorder characterized by recurring abdominal pain and discomfort, as well as alterations in bowel habits without demonstrable pathology.1 It is prevalent in the developed world, with 10-15% of...

NAFLD: Hepatic Manifestation of Metabolic Syndrome

Asia Muhammad, ND Tolle Causam Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome (MetS). NAFLD (also referred to as NASH, or non-alcoholic steatohepatitis) constitutes a spectrum of simple steatosis, steatohepatitis, and...

CD vs NCGS – My Patient Tested Negative for Celiac – Now What?

McKenzie Treloar Mescon, ND Tolle Totum I am sure I am not alone that patients seek my help in understanding their reaction to gluten when they have tested negative for celiac disease. This article is a summary of my efforts to clear the haze around gluten sensitivity...

The COHERENT Method

Matt Marturano, ND Tolle Totum A Biopsychosocial Approach to Functional Digestive Disorders Since the release of the Rome IV criteria and a series of articles in a special issue of Gastroenterology (Volume 150, Issue 6, May 2016), there has been an upsurge in interest...

Hydrogen Sulfide Dysbiosis: A Case Study

Nirala Jacobi, BHSc, ND Naturopathic Perspective “Mary,” a 65-year-old woman, was referred to me for further treatment for small intestinal bacterial overgrowth (SIBO). She had been given the diagnosis of SIBO in 2015 following a lactulose breath test, and despite...

Love Your Microbiome: Creating Homeostasis in Our Micro-World

Dr. Maria Del Mar Rodriguez-Berrios, ND This article reviews how early-life microbial exposures, antibiotic use, birth mode, and diet shape gut microbiome diversity and immune homeostasis across the lifespan. It summarizes mechanisms linking dysbiosis to barrier...

Leaky Gut: Is There a Test for That?

Alisun Bonville, ND Docere Leaky gut, ie, increased intestinal permeability, is a term that gets a lot of attention on health blogs and advertisements these days. Many Americans are curious about increased intestinal permeability and believe it to be a contributing...

Biofilms: What Have We Learned from the Research?

Paul S. Anderson, NMD Docere The medical relevance of biofilms in human illness is better understood now than ever before. A simple PubMed search using the terms “biofilm” and “human” yields 14 417 publications – an indication of the breadth and depth of research on...

Archived Case Studies and Featured Content

Childhood Trauma and Mental Health: A Systems Biology Approach to Treatment-Resistant Anxiety and OCD

Childhood Trauma and Mental Health: A Systems Biology Approach to Treatment-Resistant Anxiety and OCD

Childhood adversity may leave lasting physiological effects that extend beyond psychological symptoms. Through a case of a 19-year-old woman with persistent anxiety, OCD, emotional eating, and hyperandrogenic metabolic dysfunction, this article examines how neuroendocrine, metabolic, immune, nutritional, and gut-brain pathways may interact—and how a systems biology approach can complement conventional psychiatric care.

Observation Over Interpretation: A Homeopathic Case of Phosphorus in an 8-Month-Old

Observation Over Interpretation: A Homeopathic Case of Phosphorus in an 8-Month-Old

When an 8-month-old developed sudden distress whenever his mother left the room, the choice between Phosphorus and Pulsatilla initially appeared uncertain. Through direct observation, a previously overlooked response to physical touch became the defining symptom guiding a Phosphorus prescription, followed by reported improvement within one week.

Listening Beyond Language: A Narrative Medicine Case Study for Neurodivergent Children

Listening Beyond Language: A Narrative Medicine Case Study for Neurodivergent Children

For neurodivergent children, communication extends beyond spoken language. Through a composite pediatric case, this article explores how narrative medicine, creative expression, sensory-aware facilitation, and caregiver co-regulation can support emotional communication, self-advocacy, and connection in children with autism, ADHD, and related developmental differences.

First, Do No Harm: Managing Pediatric Klebsiella Dysbiosis Without Delaying Diagnosis

First, Do No Harm: Managing Pediatric Klebsiella Dysbiosis Without Delaying Diagnosis

A young child with recurrent abdominal pain, bloating, constipation, sleep disturbances, and behavioral changes experienced repeated symptom improvement during integrative treatment targeting intestinal dysbiosis. This case examines the challenges of managing suspected Klebsiella-associated symptoms while navigating inconsistent treatment across two households, parental hesitation toward additional testing, and the possibility of an underlying inflammatory bowel disorder.

Medication-Induced Kidney Injury: Mechanisms, Risk Factors, and Prevention

Medications may account for an estimated 20% of community- and hospital-acquired acute kidney injury, with risk amplified by CKD, older age, chronic disease, dehydration, and polypharmacy. This review examines the major mechanisms of drug-induced nephrotoxicity and practical strategies for medication review, hydration, renal monitoring, and prevention.

Low Testosterone and Cardiovascular Disease: Risk Marker, Mediator, or Both?

Low testosterone is consistently associated with adverse cardiovascular outcomes, but whether it is a cause of vascular disease or a marker of underlying metabolic and inflammatory dysfunction remains unresolved. This review examines the epidemiology, vascular mechanisms, hypertension and atherosclerosis data, TRAVERSE findings, and the cardiovascular implications of TRT-induced erythrocytosis.

Cardiovascular Risk Assessment in Men: A Naturopathic Cardiology Perspective

Cardiovascular risk extends beyond LDL cholesterol and the standard lipid panel. This review explores how plaque biology, inflammation, oxidation, metabolic and hormonal health, advanced biomarkers, CGM, and cardiovascular imaging can complement established therapies to create a more individualized approach to cardiovascular risk assessment in men.

Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance

Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.

Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance

Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.

Advanced Inflammatory Breast Cancer: Complete Response with Naturopathic and Immuno-Oncology Treatment

This case follows a 44-year-old woman with inflammatory breast cancer that progressed to osseous metastatic disease and was managed through a multimodal naturopathic, immune-directed, and conventional oncology strategy. Serial imaging and molecular surveillance ultimately demonstrated complete metabolic response, zero circulating tumor cells, and repeatedly undetectable ctDNA, highlighting the potential value of adaptive, interdisciplinary integrative oncology care.

Ketogenic Diet in Metastatic Breast Cancer: An Integrative Oncology Case Study

Can a ketogenic diet play a supportive role during treatment for advanced breast cancer? This case follows a 34-year-old woman with metastatic HER2-positive breast cancer who adopted a ketogenic diet and broader lifestyle changes alongside chemotherapy and HER2-targeted therapy, while examining the evolving evidence, potential metabolic benefits, and limitations of ketogenic diets in cancer care.

Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report

Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.

Custom Publishing

Quantum Energy Effects on Cell Recovery Rates

Quantum Energy Effects on Cell Recovery Rates

Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...

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