CHRIS D. MELETIS, ND Autoimmune diseases afflict a considerable portion of the population, with recent numbers indicating that 15.9% of the US population, or 41 million people, suffer from an autoimmune...
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Table of Contents | 2021
Celiac Disease: The Importance of Adequate Management
KARLY MCMASTER, ND While the standard of care following a diagnosis of celiac disease (CD) is to prescribe a gluten-free diet (GFD), the recommended long-term management and monitoring of the condition is poorly understood. Too often, patients with CD...
Immune Response to Viruses: How Sleep/Wake Cycles Impact Clinical Outcome
TANYA LEE, ND The circadian system is a powerful regulatory system that guides the physiology of living organisms through synchronizing physiological processes to the external environment. This system of ultimate homeostatic regulation has evolved over time and...
Toxicity & Chronic Illness: Why Naturopathic Doctors Must Lead
KERI LAYTON, ND Every generation of naturopathic doctors decries the rising generation as an erosion of true naturopathy. Let me settle into my rocking chair and confess: I’m no better. While I lament the opportunity lost by older NDs who have dodged...
Multiple Sclerosis & Autoimmunity: The Impact of the Microbiome Keeps Getting Larger
MICHAËL FRIEDMAN, ND Abstract Multiple sclerosis (MS) is a chronic neuroinflammatory and demyelinating disorder increasingly linked to gut dysbiosis and immune dysregulation. Research shows that the gut microbiome shapes microglial maturation, blood–brain...
Endocannabinoids & Autoimmunity
JAKE F. FELICE, ND, LMP Autoimmune conditions and diseases of the nervous system are typically chronic, often have an early age of onset, and frequently cause significant pain, debility, and suffering. Autoimmunity is an...
Autoimmunity: The Mitochondrial Connection
CATHERINE CLINTON, ND Abstract Autoimmune diseases, now affecting over 23 million Americans, are closely linked to mitochondrial dysfunction and impaired regulatory T cell (Treg) activity. Mitochondria influence both innate and adaptive immunity, with mitochondrial...
Atopy & the Microbiome
JACLYN CHASSE-SMEATON, ND Atopic dermatitis (AD) dramatically impacts pediatric health and quality of life of the family as a whole. Although the pathogenesis of AD has not been clearly elucidated, there are multiple factors at...
EMF Exposure: Neuropsychiatric Effects
YASAMAN TASALLOTI, ND Since the start of the COVID-19 pandemic, there has been an increase in the utilization of technology to work, learn, and connect from home. To a great degree, this has been a welcomed solution in terms of convenience...
Notes from the Field: October, 2020
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Healing Through Listening- Part 2
JAMES SENSENIG, ND RICK KIRSCHNER, ND, VNMI This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Anxiety, Depression, and Insomnia: Treatment Using the Hippocratic Philosophy
CHRIS D. MELETIS, ND The philosophy of Hippocrates has been shown over the past 2400 years to not only have merit but also notable scientific veracity. Hippocrates advocated a natural approach to the treatment of diseases and emphasized the need for harmony...
More Than the Sum of Our Parts: The Role of Unconscious Stress in Chronic Illness
ERIN HAYFORD, ND The ultimate goal of any naturopathic medical practice is to identify and treat the cause of the illness rather than mitigate or suppress the expression – the symptoms – of disease. Through our holistic lens, we understand that...
The ECS, Cannabis, & Sleep
JAKE F. FELICE, ND, LMP Sleep is a dynamic and essential activity that involves a multitude of physiologic processes. Proper sleep assists the body with tissue repair, immune maintenance, memory storage, appetite, blood sugar control, blood...
Defeating Depression: A Holistic Approach
CHRISTINA BJORNDAL, ND SYDNEY SPEER Now, more than ever, our society is being affected by continually rising rates of mental illness. Depression is the leading cause of disability in the United States for people ages 15-44,...
Archived Case Studies and Featured Content
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Dr. Chris D Meletis Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Adam Livingston: The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
https://youtube.com/shorts/KiCTEZDh3mc
Dr. Bush Bradley And The Role of Histamine and Serotonin in Upper GI Motility
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Akkermansia muciniphila: Clinical Insights on a Next-Generation Probiotic
Sara Love, ND A clinician’s guide to when—and when not—to use A. muciniphila: evidence for gut-barrier support, metabolic and immune effects, pasteurized vs live formulations, and patient selection. Abstract Akkermansia muciniphila is an emerging “next-generation”...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
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Featured News
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Naturopathic Doctor Continues Walk Across USA for Health Equity
Fargo, ND - Dennis Godby, 69, ND, MA, a Sacramento, CA-Licensed Naturopathic Doctor (ND), to raise awareness across the USA of significant health disparities, and support the “Health Equity,” movement, will continue his inspiring 756 mile walking trek across America...
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