SAM N. CLOUTHIER, BHSC, ND Bipolar disorder is a complex illness that affects approximately 2% of the Canadian population and affects males and females in equal numbers.1 Currently, typical treatment protocols for bipolar...
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Table of Contents | 2021
Our Bugs and Our Brains
JESSICA BRANDES, ND Abstract The human microbiome exerts profound influence on neurodevelopment, stress resilience, mood regulation, and cognitive aging. Evidence shows that early-life microbial exposures shape immune and brain maturation, while disruptions—such as...
Sceletium tortuosum: A South African Plant for Mood and Stress
JEREMY APPLETON, ND Sceletium tortuosum (aka Mesembryanthemum tortuosum) is a South African plant medicine with a centuries-long history of use. Not all Sceletium preparations are alike, owing to the presence or absence of standardization,...
Perimenopause: An Undertreated Phase in Women’s Reproductive Lives
LISA BRENT, ND, LAc Perimenopause is the time period in which women transition from premenopause (the reproductive years) into menopause. Typically, these changes occur between the ages of 40 and 51 and usually last about 4 years. Perimenopause...
The Reproductive Microbiome: Profound Implications of New Research
SARAH WYLIE, ND and JACLYN CHASSE-SMEATON, ND Once upon a time, I attended the birth of a patient in a teaching hospital in Vermont. The baby was born and crying healthfully at her mother’s breast, and it was time for the mother’s uterus to contract...
The Microbial Endocrine System
GUY CITRIN, ND I assume many of my colleagues have patients who present similarly. I myself have found that my non-serious chronically ill patients often present with similar symptoms. Clinical responses to...
Pregnenolone & Its Metabolites
CARRIE DECKER, ND When we speak of hormones, we often think of those that play a role in mediating sexual function: estrogen, testosterone, and progesterone. These hormones come from the common base molecule of cholesterol, and all 3 derive from the mother...
The ECS-Adrenal-Stress Axis
JAKE F. FELICE, ND, LMP The endocannabinoid system (ECS) responds not only to cannabis and cannabinoid molecules; it is also positively affected by diet, exercise, acupuncture, probiotics, prebiotics, acupuncture, osteopathic...
Treating Infertility: A Whole-Body Approach Including Mayan Uterine Massage & Seed Cycling
ANA LARA, NMD Fertility is a topic that many women have strong personal feelings about. I often hear my female patients say, “Having children is the one thing I am designed to do, yet I can’t get pregnant. I feel less of a...
Healthy Conception and Pregnancy: The Role of Nitric Oxide and Other Critical Factors
CHRIS D. MELETIS, ND Modern couples face many obstacles to becoming pregnant or giving birth to a healthy baby, and the distribution of contributing factors appears to be nearly equal between male and female. According to the Centers for Disease...
Healing Through Listening- Part 1
JAMES SENSENIG, ND RICK KIRSCHNER, ND, VNMI This article joins a series of articles in NDNR that are based on transcripts of the Naturopathic Medicine Institute (NMI)’s Wednesday morning call-in program, The Vital Conversation. The program is hosted by...
Notes from the Field: September, 2020
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Medicinal Mushrooms: Their Role in GI Cancers
MICHAEL TRAUB, ND, DHANP, FABNO Medicinal mushrooms play an essential role in the treatment of cancer. In the past decade, the use of mycotherapy has attracted much attention in the efforts to understand various benefits and the possible mechanisms through which...
Digestive, Skin, Immune Issues: A Complicated Case
MATTHEW STRICKLAND, ND LW, a 22-year-old female, presented to my office with a problem list that included digestive issues, skin issues, weak immune system, food/allergy sensitivities, and hormonal imbalance. LW reported that all of her health problems started at...
Vitalism as the Standard of Care- Part 2
JAMES SENSENIG, ND LETITIA DICK, ND, VNMI This article joins a series of articles in NDNR that are based on transcripts of the Naturopathic Medicine Institute (NMI)’s Wednesday morning call-in program, The Vital Conversation. The program is hosted by...
Archived Case Studies and Featured Content
The Silent Male Infertility Epidemic: How Men Can Protect & Restore Their Fertility
Dr. Samuel Madeira, N.M.D. Infertility affects about 180 million people worldwide and at least 15% of couples in the United States alone. The far-too-often overlooked factor in fertility medicine today is the male contribution, accounting for the cause of 30-50% of...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
From PCOS to PMOS: What the Name Change Means for Your Practice
Dr. Jaclyn Smeaton, ND A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...
Collaborative Fertility Care: How Naturopathic Doctors and Nurse Practitioners Can Expand Integrative Treatment Options
Dr. Nora Pope ND, FCP A clinical exploration of how collaborative ND–NP care can bridge prescribing limitations, integrate restorative fertility strategies, and expand access to individualized reproductive treatment. This article examines the clinical value of...
Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body
This article examines mind-body medicine as a clinical framework that bridges physical symptoms with lived experience through somatic awareness, interoception, and compassionate presence. Using theory, case illustration, and relational neuroscience, it highlights how nervous system regulation and authentic connection can facilitate deep, lasting healing.
Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
Dr. Nicole Roberts, ND A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Abstract In this case report, we see a 48-year-old female,...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
Dr. Leslie Solomonian, ND An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Abstract This article examines...
Borage (Borago officinalis): Botanical Ally for Courage, Self-Expression, and the Restoration of Self-Love
An integrative exploration of borage’s traditional uses, phytochemistry, and clinical applications in supporting self-compassion, stress resilience, and emotional regulation in naturopathic practice. Dr. Katelyn Mudry, ND, MSc Introduction Over the past year,...
Lavender Essential Oil and Anxiety Management: A Case Study
A case-based examination of oral lavender essential oil as a non-pharmaceutical intervention for generalized anxiety disorder in a patient seeking evidence-informed, integrative care. Dr. Jennifer Brusewitz ND and Sophie Tajadod Abstract This case study explores the...
Olive Oil and Mental Health: A Scoping Review of Depression, Anxiety, and Stress Outcomes
A comprehensive scoping review explores how olive oil and its bioactive constituents may influence depression, anxiety, stress, and other mental health outcomes across clinical trials, epidemiological research, and preclinical models. Dr. Monique Aucoin ND MSc Vanessa...
Desperate patients are looking for you
Right now, someone in your community is Googling "how to get off antidepressants safely."They're not alone. Searches for "antidepressant withdrawal" are up 200%. In Canada, taper-related searches have increased 160 to 180% over the last few years.They're...
New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes
Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery. A...
Microplastics and Nanoplastics: Emerging Health Risks and Clinical Implications
Frasier Smith, ND Abstract Understanding how persistent plastic particles infiltrate human physiology—and what clinicians can do to help patients mitigate exposure and health impacts. Micro- and nanoplastic exposure is now ubiquitous, with growing evidence linking...
Quantum Energy Field and Its Effects on Cellular ATP Production Rates in Human Cells
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Quantum Upgrade based on Leela Quantum technology, influences adenosine triphosphate (ATP) production in human cell lines. This double-blind...
Olive Oil and Mental Health: A Scoping Review of Depression, Anxiety, and Stress Outcomes
A comprehensive scoping review explores how olive oil and its bioactive constituents may influence depression, anxiety, stress, and other mental health outcomes across clinical trials, epidemiological research, and preclinical models. Dr. Monique Aucoin ND MSc Vanessa...
Desperate patients are looking for you
Right now, someone in your community is Googling "how to get off antidepressants safely."They're not alone. Searches for "antidepressant withdrawal" are up 200%. In Canada, taper-related searches have increased 160 to 180% over the last few years.They're...
New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes
Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery. A...
Microplastics and Nanoplastics: Emerging Health Risks and Clinical Implications
Frasier Smith, ND Abstract Understanding how persistent plastic particles infiltrate human physiology—and what clinicians can do to help patients mitigate exposure and health impacts. Micro- and nanoplastic exposure is now ubiquitous, with growing evidence linking...
Quantum Energy Field and Its Effects on Cellular ATP Production Rates in Human Cells
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Quantum Upgrade based on Leela Quantum technology, influences adenosine triphosphate (ATP) production in human cell lines. This double-blind...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
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Featured News
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
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