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Table of Contents | 2021

Our Bugs and Our Brains

JESSICA BRANDES, ND Abstract The human microbiome exerts profound influence on neurodevelopment, stress resilience, mood regulation, and cognitive aging. Evidence shows that early-life microbial exposures shape immune and brain maturation, while disruptions—such as...

Sceletium tortuosum: A South African Plant for Mood and Stress

JEREMY APPLETON, ND Sceletium tortuosum (aka Mesembryanthemum tortuosum) is a South African plant medicine with a centuries-long history of use. Not all Sceletium preparations are alike, owing to the presence or absence of standardization,...

The Reproductive Microbiome: Profound Implications of New Research

SARAH WYLIE, ND and JACLYN CHASSE-SMEATON, ND  Once upon a time, I attended the birth of a patient in a teaching hospital in Vermont. The baby was born and crying healthfully at her mother’s breast, and it was time for the mother’s uterus to contract...

The Microbial Endocrine System

GUY CITRIN, ND I assume many of my colleagues have patients who present similarly. I myself have found that my non-serious chronically ill patients often present with similar symptoms. Clinical responses to...

Pregnenolone & Its Metabolites

CARRIE DECKER, ND  When we speak of hormones, we often think of those that play a role in mediating sexual function: estrogen, testosterone, and progesterone. These hormones come from the common base molecule of cholesterol, and all 3 derive from the mother...

The ECS-Adrenal-Stress Axis

JAKE F. FELICE, ND, LMP  The endocannabinoid system (ECS) responds not only to cannabis and cannabinoid molecules; it is also positively affected by diet, exercise, acupuncture, probiotics, prebiotics, acupuncture, osteopathic...

Healing Through Listening- Part 1

JAMES SENSENIG, ND  RICK KIRSCHNER, ND, VNMI This article joins a series of articles in NDNR that are based on transcripts of the Naturopathic Medicine Institute (NMI)’s Wednesday morning call-in program, The Vital Conversation. The program is hosted by...

Notes from the Field: September, 2020

JARED L. ZEFF, ND, VNMI, LAC  The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...

Medicinal Mushrooms: Their Role in GI Cancers

MICHAEL TRAUB, ND, DHANP, FABNO  Medicinal mushrooms play an essential role in the treatment of cancer. In the past decade, the use of mycotherapy has attracted much attention in the efforts to understand various benefits and the possible mechanisms through which...

Digestive, Skin, Immune Issues: A Complicated Case

MATTHEW STRICKLAND, ND LW, a 22-year-old female, presented to my office with a problem list that included digestive issues, skin issues, weak immune system, food/allergy sensitivities, and hormonal imbalance. LW reported that all of her health problems started at...

Vitalism as the Standard of Care- Part 2

JAMES SENSENIG, ND  LETITIA DICK, ND, VNMI  This article joins a series of articles in NDNR that are based on transcripts of the Naturopathic Medicine Institute (NMI)’s Wednesday morning call-in program, The Vital Conversation. The program is hosted by...

Archived Case Studies and Featured Content

Naturopathic Medical Education: A Comprehensive Curriculum

Naturopathic Medical Education: A Comprehensive Curriculum

Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...

Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems

ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...

Fluoxetine During Development Damaged Hearing and the Brainstem

ARCADIA TALLMAN   Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing...

Fifteen Questions to Get Patient Commitment

Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...

IS TYLENOL SAFE DURING PREGNANCY?

Understanding Risk Factors, Not Causation Learn how much Tylenol pregnant women can safely take, what risk factors matter, and why glutathione status—not acetaminophen itself—determines safety during pregnancy.   IN THIS ARTICLE • Key Takeaways: Tylenol Safety...

Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body

This article examines mind-body medicine as a clinical framework that bridges physical symptoms with lived experience through somatic awareness, interoception, and compassionate presence. Using theory, case illustration, and relational neuroscience, it highlights how nervous system regulation and authentic connection can facilitate deep, lasting healing.

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