NODE SMITH, ND As an individual's free time increases, so does that person's sense of well-being -- but only up to a point. Too much free time can be also be a bad thing, according to research published by the American Psychological Association. "People often complain...
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Table of Contents | 2021 | September
Intracrine Steroid Biosynthesis
ANDREW L. RUBMAN, ND, FABNE SUSAN GORDON, PHD, LMT In the May 2021 issue of NDNR, Carrie Decker, ND, wrote an excellent article titled “The Anti-Aging Effects of DHEA.”1 The present article also discusses...
Epigenetics: Growing Up in a Toxic World – Part 2
CHRIS D. MELETIS, ND Abstract In Part II of this series on pediatric epigenetics, Dr. Chris Meletis explores how modern environmental exposures—including stress, sedentary lifestyles, EMFs, and widespread toxins—can lead to harmful epigenetic modifications that...
Immune Function & Competence: Gut Microbial Influences
MICHELLE MADDUX, ND Abstract This article reviews the critical role of the gut microbiome in immune system development, barrier integrity, and regulation of inflammatory and autoimmune responses. It highlights mechanisms such as short-chain fatty acid...
Tick Tubes: Stopping Lyme in Its Tracks
JACOB SCHOR, ND, FABNO This past winter, my wife and I saved all the cardboard tubes at the core of toilet paper and paper towel rolls. Today (early March), I will use them to make “tick tubes.” Our nearest neighbor, a...
Wired for Self-Healing- Part 2
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Notes from the Field: March, 2021
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Urinary Incontinence: A Common Problem for Elderly Women
THOMAS A. KRUZEL, ND Urinary incontinence affects 23-31% of the female elderly population1 and is estimated to affect 50-65% of both sexes in hospitals and nursing homes.2 Generally, older women experience more...
Nutraceuticals for Knee OA: Naturopathic Evidence-Based Strategies
DYLAN W. KRUEGER, NMD Americans work tremendously hard for the vast majority of their lives, often with the idyllic dream of an active and exciting retirement. Unfortunately, many folks reach retirement battered, beaten, and struggling with chronic diseases and...
Dementia: Depression as a Risk Factor
ROMI FUNG, ND, MSC The “Baby Boomer” generation, defined as people born between 1946 and 1964, is a demographic cohort consisting of 76 million people around the globe born during post-World War II (WWII).1 A baby boom...
Archived Case Studies and Featured Content
Breath of Fresh Air for the Profession: Reflections from AANP 2026 in Madison
The 2026 American Association of Naturopathic Physicians (AANP) Convention arrived in Madison, Wisconsin, under unusual skies. Wildfire smoke had drifted across the region, leaving the city enveloped in smoke and fog as naturopathic physicians, students, educators,...
Daraxonrasib and Pancreatic Cancer: A Breakthrough for Precision and Integrative and Naturopathic Oncology
Daraxonrasib is reshaping the therapeutic landscape of RAS-driven pancreatic cancer and raising new considerations for integrative clinicians. This article explores pan-RAS inhibition alongside practical strategies for nutrition, exercise, symptom management, and careful evaluation of botanical and nutrient interactions within a precision integrative oncology framework.
Advanced Inflammatory Breast Cancer: Complete Response with Naturopathic and Immuno-Oncology Treatment
This case follows a 44-year-old woman with inflammatory breast cancer that progressed to osseous metastatic disease and was managed through a multimodal naturopathic, immune-directed, and conventional oncology strategy. Serial imaging and molecular surveillance ultimately demonstrated complete metabolic response, zero circulating tumor cells, and repeatedly undetectable ctDNA, highlighting the potential value of adaptive, interdisciplinary integrative oncology care.
Ketogenic Diet in Metastatic Breast Cancer: An Integrative Oncology Case Study
Can a ketogenic diet play a supportive role during treatment for advanced breast cancer? This case follows a 34-year-old woman with metastatic HER2-positive breast cancer who adopted a ketogenic diet and broader lifestyle changes alongside chemotherapy and HER2-targeted therapy, while examining the evolving evidence, potential metabolic benefits, and limitations of ketogenic diets in cancer care.
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Root-Cause Diabetes Prevention: A Naturopathic Approach to Insulin Resistance and Metabolic Health
Jack Duke, ND Type 2 diabetes develops over years of progressive metabolic dysfunction. This article reviews the pathophysiology of insulin resistance, highlights strategies for early detection, and presents practice-based outcomes from a 12-week naturopathic...
Mental Time Reversal Breathing, Perception Biology, and Telomere-Regulated Longevity: An Integrative Neuro-Endo-Immunologic Framework
Majid Michael Sababi, ND, DC, MS, MD*, MUAc, ABDA This article explores how rhythmic breathing, mental time-reversal visualization, and psychoneuroimmunology may influence autonomic regulation, stress physiology, and telomere biology to support healthy aging...
CIRS, Water-Damaged Buildings, and Parkinson’s Disease: An Underrecognized Environmental Driver of Neurodegeneration
Eric Dorninger, ND, Lac Emerging evidence suggests that Chronic Inflammatory Response Syndrome (CIRS) caused by exposure to water-damaged buildings may contribute to neuroinflammation, Parkinsonian symptoms, and potentially modifiable pathways of...
Five Days of Oral Essential Oils Produced Symptom Relief Equal to Ten Days of Penicillin V
Physicians assessed that 58 of 67 patients on oral essential oil capsules had avoided antibiotics, and 89 percent of those patients would use the capsules again for their next sore throat. Patients with acute sore throat obtained symptom relief from five days...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
Mental Time Reversal Breathing, Perception Biology, and Telomere-Regulated Longevity: An Integrative Neuro-Endo-Immunologic Framework
Majid Michael Sababi, ND, DC, MS, MD*, MUAc, ABDA This article explores how rhythmic breathing, mental time-reversal visualization, and psychoneuroimmunology may influence autonomic regulation, stress physiology, and telomere biology to support healthy aging...
CIRS, Water-Damaged Buildings, and Parkinson’s Disease: An Underrecognized Environmental Driver of Neurodegeneration
Eric Dorninger, ND, Lac Emerging evidence suggests that Chronic Inflammatory Response Syndrome (CIRS) caused by exposure to water-damaged buildings may contribute to neuroinflammation, Parkinsonian symptoms, and potentially modifiable pathways of...
Five Days of Oral Essential Oils Produced Symptom Relief Equal to Ten Days of Penicillin V
Physicians assessed that 58 of 67 patients on oral essential oil capsules had avoided antibiotics, and 89 percent of those patients would use the capsules again for their next sore throat. Patients with acute sore throat obtained symptom relief from five days...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
The Missing Question: How Occupational Heavy Metal Exposure Contributed to Severe Testosterone Deficiency in a Young Male
Glenn B. Gero, ND, DSc, M.E.S., R.H. (AHG), EndoANP Kareem Kandil, MD, ND A case study demonstrating how a simple occupational history uncovered chronic heavy metal exposure as a likely contributor to severe hypogonadism, highlighting the critical role of...
Reduction of Thyroid Antibodies with Tirzepatide in Hashimoto’s Thyroiditis: A Metabolic-Immune Case Report
Dr. Valerie Gettings, NMD A case report exploring how low-dose tirzepatide improved insulin resistance, thyroid function, and thyroid autoantibody levels in a patient with Hashimoto’s thyroiditis, highlighting the emerging role of metabolic therapies in...
16-Hydroxyestrone, Enterohepatic Recirculation, and Dysmenorrhea: Personalizing Hormone Care Through Estrogen Metabolite Testing
Dr. Liz Bartman, ND A case-based exploration of how urinary estrogen metabolites can reveal hidden patterns of estrogen recirculation, gut-liver dysfunction, and hormone clearance that contribute to menstrual pain and heavy bleeding. This case report examines a...
Nigella sativa: The Ancient Herbal Remedy Supporting Thyroid Resilience in Hashimoto’s Thyroiditis
Lillea Hartwell, ND A comprehensive review of Nigella sativa seed oil, its active constituents, safety profile, pharmacology, and emerging clinical evidence for supporting immune regulation and thyroid function in Hashimoto’s thyroiditis. This monograph reviews...
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Custom Publishing
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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