Complex Chronic Disease Saved by a Genetic Hormone Profile WINNIE SIU, ND As clinicians, we often come across complex and challenging cases. Many of our patients have been diagnosed with complex chronic conditions such as mast cell activation syndrome...
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Table of Contents | 2022
Botanical Formulations Part II
JAMES SENSENIG, ND JARED ZEFF, ND, VNMI, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through clinical...
Amyotrophic Lateral Sclerosis
Addressing Mitochondrial Alterations in C9orf72-ALS SAMANTHA PRYOR, ND Last year my first submission to NDNR was about microbiome alterations found in amyotrophic lateral sclerosis (ALS). I consider that article is essential reading for any clinician who...
Neuropathy & Nutrition
What are the Nerves Trying to Communicate? CHRIS D. MELETIS, ND About 7-10% of the population suffers from neuropathic pain and doctors are often unable to effectively and completely treat this condition.1 Often, this is because we try to address the problem after...
Reevaluating RICE
The Cold Truth About Ice & Inflammation SIERRA GONCHAROFF, ND The use of ice for acute musculoskeletal injuries has been popular for decades since Gabe Mirkin, MD coined the RICE (rest, ice, compression, elevation) protocol in 1978 in his best-selling...
Botanical Synergy (Part 1)
Applying Network Pharmacology to Pharmaceuticals & Botanical Medicine JAKE FELICE, ND, LMP New advances in our understanding of network pharmacology now support the wisdom of plant medicine and botanical synergy. This understanding of synergy and its mechanisms...
Illuminating Pain Management
The Benefits of Acupuncture and Low-Level Laser Therapy SHAWN M. CARNEY, ND Naturopathic physicians are often sought out by patients frustrated with the superficial quality of care they receive from some conventional medical doctors; those seeking pain relief are no...
Homeopathic Injections
Unique Treatment for Musculoskeletal & Smooth Muscle Pain BILL CARADONNA, RPH, ND Like many other doctors, I have had patients with musculoskeletal pain come to my office after having tried all manner of allopathic and other natural medicine treatment...
Fight, Flight, or Freeze
Applying Polyvagal Theory to Treat a Traumatized Patient JENNIFER BRUSEWITZ, ND ELIZABETH HOLLOWAY, ND The polyvagal theory, introduced by Stephen Porges, PhD, in 1995, explains how human adaptive responses are modulated through the autonomic nervous system...
Notes from the Field #33
June 2022 JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s...
Addressing Long COVID
Naturopathic Strategies for Neuropsychiatric Symptoms YASAMAN TASALLOTI, ND Abstract Long COVID presents with persistent neuropsychiatric symptoms such as fatigue, brain fog, sleep disturbances, and depression, largely driven by chronic inflammation,...
“Hysterical” Chest Spasm
Suspected Conversion Disorder Treated by Homeopathy IAN SPOHN, ND Conversion disorder is a conventional psychiatric diagnosis, a rare example where Western medicine acknowledges the mind-body link. Also known as functional neurological symptom disorder,...
A Hard Day’s Night
Circadian Disruption & Medical School FRASER SMITH, MATD, ND It’s been a hard day’s night, and I’ve been working like a dog. It’s been a hard day’s night; I should be sleeping like a log.” So sang John Lennon on the title song to the Beatles...
Botanical Formulations
Part I JAMES SENSENIG, ND JARED ZEFF, ND, VNMI, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy...
Brain Health & Dysfunction
The Role of Cerebellar Atrophy CHRIS D. MELETIS, ND Mind-body medicine is the ability of the brain to improve the health of the body. However, if cognitive function is not operating at peak capacity, the brain will not be able to impact bodily health. In this...
Archived Case Studies and Featured Content
Breath of Fresh Air for the Profession: Reflections from AANP 2026 in Madison
The 2026 American Association of Naturopathic Physicians (AANP) Convention arrived in Madison, Wisconsin, under unusual skies. Wildfire smoke had drifted across the region, leaving the city enveloped in smoke and fog as naturopathic physicians, students, educators,...
Daraxonrasib and Pancreatic Cancer: A Breakthrough for Precision and Integrative and Naturopathic Oncology
Daraxonrasib is reshaping the therapeutic landscape of RAS-driven pancreatic cancer and raising new considerations for integrative clinicians. This article explores pan-RAS inhibition alongside practical strategies for nutrition, exercise, symptom management, and careful evaluation of botanical and nutrient interactions within a precision integrative oncology framework.
Advanced Inflammatory Breast Cancer: Complete Response with Naturopathic and Immuno-Oncology Treatment
This case follows a 44-year-old woman with inflammatory breast cancer that progressed to osseous metastatic disease and was managed through a multimodal naturopathic, immune-directed, and conventional oncology strategy. Serial imaging and molecular surveillance ultimately demonstrated complete metabolic response, zero circulating tumor cells, and repeatedly undetectable ctDNA, highlighting the potential value of adaptive, interdisciplinary integrative oncology care.
Ketogenic Diet in Metastatic Breast Cancer: An Integrative Oncology Case Study
Can a ketogenic diet play a supportive role during treatment for advanced breast cancer? This case follows a 34-year-old woman with metastatic HER2-positive breast cancer who adopted a ketogenic diet and broader lifestyle changes alongside chemotherapy and HER2-targeted therapy, while examining the evolving evidence, potential metabolic benefits, and limitations of ketogenic diets in cancer care.
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Root-Cause Diabetes Prevention: A Naturopathic Approach to Insulin Resistance and Metabolic Health
Jack Duke, ND Type 2 diabetes develops over years of progressive metabolic dysfunction. This article reviews the pathophysiology of insulin resistance, highlights strategies for early detection, and presents practice-based outcomes from a 12-week naturopathic...
Mental Time Reversal Breathing, Perception Biology, and Telomere-Regulated Longevity: An Integrative Neuro-Endo-Immunologic Framework
Majid Michael Sababi, ND, DC, MS, MD*, MUAc, ABDA This article explores how rhythmic breathing, mental time-reversal visualization, and psychoneuroimmunology may influence autonomic regulation, stress physiology, and telomere biology to support healthy aging...
CIRS, Water-Damaged Buildings, and Parkinson’s Disease: An Underrecognized Environmental Driver of Neurodegeneration
Eric Dorninger, ND, Lac Emerging evidence suggests that Chronic Inflammatory Response Syndrome (CIRS) caused by exposure to water-damaged buildings may contribute to neuroinflammation, Parkinsonian symptoms, and potentially modifiable pathways of...
Five Days of Oral Essential Oils Produced Symptom Relief Equal to Ten Days of Penicillin V
Physicians assessed that 58 of 67 patients on oral essential oil capsules had avoided antibiotics, and 89 percent of those patients would use the capsules again for their next sore throat. Patients with acute sore throat obtained symptom relief from five days...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
Mental Time Reversal Breathing, Perception Biology, and Telomere-Regulated Longevity: An Integrative Neuro-Endo-Immunologic Framework
Majid Michael Sababi, ND, DC, MS, MD*, MUAc, ABDA This article explores how rhythmic breathing, mental time-reversal visualization, and psychoneuroimmunology may influence autonomic regulation, stress physiology, and telomere biology to support healthy aging...
CIRS, Water-Damaged Buildings, and Parkinson’s Disease: An Underrecognized Environmental Driver of Neurodegeneration
Eric Dorninger, ND, Lac Emerging evidence suggests that Chronic Inflammatory Response Syndrome (CIRS) caused by exposure to water-damaged buildings may contribute to neuroinflammation, Parkinsonian symptoms, and potentially modifiable pathways of...
Five Days of Oral Essential Oils Produced Symptom Relief Equal to Ten Days of Penicillin V
Physicians assessed that 58 of 67 patients on oral essential oil capsules had avoided antibiotics, and 89 percent of those patients would use the capsules again for their next sore throat. Patients with acute sore throat obtained symptom relief from five days...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
The Missing Question: How Occupational Heavy Metal Exposure Contributed to Severe Testosterone Deficiency in a Young Male
Glenn B. Gero, ND, DSc, M.E.S., R.H. (AHG), EndoANP Kareem Kandil, MD, ND A case study demonstrating how a simple occupational history uncovered chronic heavy metal exposure as a likely contributor to severe hypogonadism, highlighting the critical role of...
Reduction of Thyroid Antibodies with Tirzepatide in Hashimoto’s Thyroiditis: A Metabolic-Immune Case Report
Dr. Valerie Gettings, NMD A case report exploring how low-dose tirzepatide improved insulin resistance, thyroid function, and thyroid autoantibody levels in a patient with Hashimoto’s thyroiditis, highlighting the emerging role of metabolic therapies in...
16-Hydroxyestrone, Enterohepatic Recirculation, and Dysmenorrhea: Personalizing Hormone Care Through Estrogen Metabolite Testing
Dr. Liz Bartman, ND A case-based exploration of how urinary estrogen metabolites can reveal hidden patterns of estrogen recirculation, gut-liver dysfunction, and hormone clearance that contribute to menstrual pain and heavy bleeding. This case report examines a...
Nigella sativa: The Ancient Herbal Remedy Supporting Thyroid Resilience in Hashimoto’s Thyroiditis
Lillea Hartwell, ND A comprehensive review of Nigella sativa seed oil, its active constituents, safety profile, pharmacology, and emerging clinical evidence for supporting immune regulation and thyroid function in Hashimoto’s thyroiditis. This monograph reviews...
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Custom Publishing
The Secret History Of Western Medicine & Big Pharma – W/ Advocate Razi Ann Berry
On the Shannon Joy radio show, Razi traced the history of medical education and the naturopathic medicine profession, and she examined the recent veto of the Florida naturopathic licensure bill, CS/SB 688. She explained how the Flexner Report and the funding...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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