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Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
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Table of Contents | 2022 | September
Genetics & Environmental Disease
Complex Chronic Disease Saved by a Genetic Hormone Profile WINNIE SIU, ND As clinicians, we often come across complex and challenging cases. Many of our patients have been diagnosed with complex chronic conditions such as mast cell activation syndrome...
Botanical Formulations Part II
JAMES SENSENIG, ND JARED ZEFF, ND, VNMI, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through clinical...
Amyotrophic Lateral Sclerosis
Addressing Mitochondrial Alterations in C9orf72-ALS SAMANTHA PRYOR, ND Last year my first submission to NDNR was about microbiome alterations found in amyotrophic lateral sclerosis (ALS). I consider that article is essential reading for any clinician who...
Neuropathy & Nutrition
What are the Nerves Trying to Communicate? CHRIS D. MELETIS, ND About 7-10% of the population suffers from neuropathic pain and doctors are often unable to effectively and completely treat this condition.1 Often, this is because we try to address the problem after...
Reevaluating RICE
The Cold Truth About Ice & Inflammation SIERRA GONCHAROFF, ND The use of ice for acute musculoskeletal injuries has been popular for decades since Gabe Mirkin, MD coined the RICE (rest, ice, compression, elevation) protocol in 1978 in his best-selling...
Botanical Synergy (Part 1)
Applying Network Pharmacology to Pharmaceuticals & Botanical Medicine JAKE FELICE, ND, LMP New advances in our understanding of network pharmacology now support the wisdom of plant medicine and botanical synergy. This understanding of synergy and its mechanisms...
Illuminating Pain Management
The Benefits of Acupuncture and Low-Level Laser Therapy SHAWN M. CARNEY, ND Naturopathic physicians are often sought out by patients frustrated with the superficial quality of care they receive from some conventional medical doctors; those seeking pain relief are no...
Homeopathic Injections
Unique Treatment for Musculoskeletal & Smooth Muscle Pain BILL CARADONNA, RPH, ND Like many other doctors, I have had patients with musculoskeletal pain come to my office after having tried all manner of allopathic and other natural medicine treatment...
Fight, Flight, or Freeze
Applying Polyvagal Theory to Treat a Traumatized Patient JENNIFER BRUSEWITZ, ND ELIZABETH HOLLOWAY, ND The polyvagal theory, introduced by Stephen Porges, PhD, in 1995, explains how human adaptive responses are modulated through the autonomic nervous system...
Archived Case Studies and Featured Content
The Supplier Show Returns November 7, 2026, Bringing Innovation, Industry Leaders and Healthcare Professionals Together
Second Annual Event Celebrates Connections, Collaboration and Driving Success in Naturopathic and Integrative Medicine Following a successful inaugural year, The Supplier Show 2026: Driving Success returns on Saturday, November 7, 2026, at the Pearson Convention...
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
Chemotherapy-induced peripheral neuropathy can persist long after cancer treatment, affecting pain, balance, function, and quality of life. This review examines evidence-informed strategies for CIPN, including Mediterranean-style nutrition, exercise, acupuncture, duloxetine, cryotherapy and compression, while identifying commonly used supplements that lack benefit or may worsen neuropathy.
Care Beyond the Cure: An Integrative Approach to Palliative Care
Palliative care is not about abandoning treatment or losing hope—it is about adding another layer of support. This article explores an integrative, interdisciplinary approach that introduces symptom management, quality-of-life support, advance care planning, and emotional and spiritual care early in the course of serious illness.
How to Get the Most from Your Cancer Doctor Visits: A Guide for Patients and Survivors
Cancer care can be complex and overwhelming, but preparation can make medical appointments more productive and less stressful. This practical checklist offers 18 strategies to help patients communicate effectively with providers, organize their care, explore treatment options, and build a collaborative medical “dream team.”
Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report
Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
Custom Publishing
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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