Inflammatory and Neural Pathways Explain Depression in Patients with Physical Pain Pain is not merely a secondary symptom of illness. It is an indicator of unresolved physiological disruption. Inflammation, far from being a defect, is the body’s coordinated response...

Trending Articles
Nanoplastics Found in Blood and Fluids Using New Laser-Based Detection Tool
Chemical Profiling of Plastic Particles Reveals Implant Risks and Long-Term Exposure Concerns Nanoplastics are synthetic polymer fragments smaller than 100 nanometers. Microplastics range in size from 100 nanometers to 5 millimeters. By comparison, a human red blood...
Mediterranean Diet and Movement Preserve Bone Density in Older Women
Structured Weight Loss Protects Lumbar and Hip Bone Density in Postmenopausal Women Older women with overweight or obesity who followed a calorie-controlled Mediterranean diet combined with regular physical activity maintained key markers of bone health over three...
Mitochondrial Disruption Explains Systemic Benzodiazepine Side Effects
New Evidence Links Long-Term Use and Withdrawal Symptoms to Cellular Energy Dysfunction Benzodiazepines impair mitochondrial signaling across multiple systems in the body, not just GABA receptors in the brain. Mitochondria play a central role in regulating cell energy...
Paternal Depression Increases ADHD and Behavioral Risk by 37%
Depressed Fathers Raise Behavioral and Social Risk in School-Aged Children Children whose fathers had depression at age 5 were up to 37% more likely to develop hyperactivity, oppositional behaviors, and ADHD symptoms by age 9, based on teacher reports. These children...
Featured Article | Anxiety/Depression/Mental Health
Public Sector Higher Ed: Slippery Slope or the Next Best Path?
Education David J. Schleich, PhD We’ve been sparring with the biomedicine industry all along the professional formation continuum (education, research, licensing) for a very long time. We have also been joining some aspects of the mainstream’s strategies for a...
Exclusive Content | Anxiety/Depression/Mental Health
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Archived Case Studies and Featured Content
A Trauma-Informed Mind-Body Approach to Chronic Illness: A Case of Early-Onset Rheumatoid Arthritis
Erin Hayford, ND A case study demonstrating how treating complex trauma—rather than suppressing symptoms—led to profound healing and personal transformation in a patient with long-standing rheumatoid arthritis. Abstract This case study explores a unique therapeutic...
Neurosensory Healing: A Holistic Approach to Stress and Emotional Wellbeing
Rob Streisfeld, NMD Explore how ancient sensory therapies—enhanced by modern technology—are revolutionizing the way we support emotional well-being, reduce stress, and promote healing. In a fast-paced, digitally saturated world, stress, anxiety, and mental health...
Preventing Alzheimer’s Before It Starts: A Root-Cause Approach for Genetic ApoE4 Risk
Stephanie Yang, ND Discover how a 53-year-old woman with a strong family history of Alzheimer’s took a proactive, root-cause approach to protect her cognitive future through lifestyle, neuroprotective therapies, and metabolic support. Abstract and Introduction...
Neurovanna Launches Customizable, White-Labeled Reports for SIBO Breath Testing
Empowering Clinics and Practitioners to Elevate Their Brand with Clinically-Relevant, Personalized Results Stillwater, MN — 7/25/25 — Neurovanna, the trusted partner in Small Intestinal Bacterial Overgrowth (SIBO) diagnostics, is proud to announce the launch of...
Exposure to Novel Information Could Promote Interest in Learning
From Ohio State University Long before they enter a classroom, people learn to identify commonplace objects like a "dog" and a "chair" just by encountering them in everyday life, with no intent to learn about what they are. A new study is one of the first to provide...
Dysfunctional Breathing Patterns in Athletes
From Ritsumeikan University Breathing patterns are an important indicator of an individual's health. A healthy individual breathes naturally using primary respiratory muscles (e.g., diaphragm muscle) that produce a rhythmic observable movement of the upper rib cage,...
Ketamine as a Rapid Antidepressant
From Northwestern University Ketamine is the speedster of antidepressants, working within hours compared to more common antidepressants that can take several weeks. But ketamine can only be given for a limited amount of time because of its many side effects. Now, a...
Homeopathy Kisses Warts Goodbye: A Gentle Alternative to Conventional Wart Treatments
SHARUM SHARIF, ND My primary care naturopathic practice has a focus on natural dermatology. I utilize a variety of naturopathic therapeutics to address skin diseases of all types, including warts, but my primary tool is homeopathy. I have successfully treated a...
Regeneration and Osteoarthritis: Addressing Joint Health Over Time
SAMUEL G OLTMAN, ND Human beings are not fragile collectibles that must be kept on the shelf in mothballs to be preserved in pristine condition. We are regenerative beings. Human beings respond to stress with strength given the proper conditions. This is the...
Why I Became a Naturopathic Doctor
Jenna Henderson, N.D. Like most naturopathic doctors, I was drawn to alternatives when I reached the limits of mainstream medicine. In my situation it was extreme, I was already in kidney failure when I enrolled in naturopathic college. By that time, I had seen the...
Can We Slow Aging in Patients? Autophagy, Mitophagy, Genetics & Epigenetics
CHRIS D. MELETIS, ND Aging – or more specifically, how to slow it down – is a topic that has fascinated scientists, doctors, and the general population for thousands of years. Yet despite our advancements in medicine and science, we still don’t know for sure...
Orthobiologics and Epicondylosis: Tendon Healing Using Microfragmented Adipose Tissue and PRP
TERRANCE MANNING II, ND, RMSK A 53-year-old male presented to the clinic with persistent right lateral elbow pain. The pain onset was insidious, yet this patient had had recurrent symptoms for several years; the most recent episode started 8 months before this...
The Death of the Live Lecture? Didactic Education: From the Flexner Report to COVID-19
FRASER SMITH, MATD, ND As I contemplated a title for this month’s column, I thought of a prototypical fake headline such as “News Flash: Naturopathic medical students prefer actual human contact to listening to screencasts!” That’s not much of a revelation....
Microneedling and PRP: A Formula for Stimulating Hair Regrowth
JANNINE KRAUSE, ND, EAMP As a practitioner that has used microneedling for the past 8 years, I would consider it one of the most effective therapies for skin rejuvenation and anti-aging therapy. Originally developed in the 1990s for treating scars and...
Why I Became a Naturopathic Doctor
Jenna Henderson, N.D. Like most naturopathic doctors, I was drawn to alternatives when I reached the limits of mainstream medicine. In my situation it was extreme, I was already in kidney failure when I enrolled in naturopathic college. By that time, I had seen the...
Can We Slow Aging in Patients? Autophagy, Mitophagy, Genetics & Epigenetics
CHRIS D. MELETIS, ND Aging – or more specifically, how to slow it down – is a topic that has fascinated scientists, doctors, and the general population for thousands of years. Yet despite our advancements in medicine and science, we still don’t know for sure...
Orthobiologics and Epicondylosis: Tendon Healing Using Microfragmented Adipose Tissue and PRP
TERRANCE MANNING II, ND, RMSK A 53-year-old male presented to the clinic with persistent right lateral elbow pain. The pain onset was insidious, yet this patient had had recurrent symptoms for several years; the most recent episode started 8 months before this...
The Death of the Live Lecture? Didactic Education: From the Flexner Report to COVID-19
FRASER SMITH, MATD, ND As I contemplated a title for this month’s column, I thought of a prototypical fake headline such as “News Flash: Naturopathic medical students prefer actual human contact to listening to screencasts!” That’s not much of a revelation....
Microneedling and PRP: A Formula for Stimulating Hair Regrowth
JANNINE KRAUSE, ND, EAMP As a practitioner that has used microneedling for the past 8 years, I would consider it one of the most effective therapies for skin rejuvenation and anti-aging therapy. Originally developed in the 1990s for treating scars and...
Pre-Education: How to Attract Motivated, Invested Patients
DANIELLE CHANDLER NDNR’s mission is to be an open forum for the entire naturopathic profession. Each issue provides readers with the most current information on clinically significant and applicable advancements within the naturopathic profession. In recognition...
Anti-Aging Skincare: A Clinical Review of Rosacea
CARRIE DECKER, ND Much to their dismay, as some patients progress through midlife, the troublesome pustules, papules, and facial redness once thought confined to puberty can resurface. Unfortunately, even though these facial changes may appear similar to acne,...
The Skin-Hormone Connection: Balancing Hormones & Healing the Skin-Together
TREVOR CATES, ND As our body’s largest and most visible organ, skin gives us outer clues about what’s happening inside the body. This includes hormonal imbalances. Acknowledging and working with the skin-hormone connection can not only help alleviate your...
Dysfunctional Breathing Patterns in Athletes
From Ritsumeikan University Breathing patterns are an important indicator of an individual's health. A healthy individual breathes naturally using primary respiratory muscles (e.g., diaphragm muscle) that produce a rhythmic observable movement of the upper rib cage,...
The ‘Journey’ of Microplastics Through the Body
From Universitat Autonoma de Barcelona A UAB research team has managed to track the behaviour of microplastics during their "journey" through the intestinal tract of a living organism and illustrate what happens along the way. The study, carried out on Drosophila...
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Featured News
Acid-Reducing Drugs Linked to Higher Risk of Migraines and Severe Headaches
Proton Pump Inhibitors Increase Migraine Risk by 70% People using proton pump inhibitors (PPIs), such as omeprazole and esomeprazole, are 70% more likely to experience migraines or severe headaches than non-users, according to a study published in Neurology Clinical...
Birth Defects More Common in IVF Pregnancies Due to Teratogenic Medication Exposure
Findings Highlight Increased Risks in ART Pregnancies Birth defects are more prevalent in pregnancies conceived through assisted reproductive technology (ART), such as IVF, with teratogenic medication exposure identified as a key contributing factor. A study...




