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2026 November Pediatrics and Developmental Health

Table of Contents | 2026 | November : Pediatrics and Developmental Health

Childhood Trauma and Mental Health: A Systems Biology Approach to Treatment-Resistant Anxiety and OCD

Childhood adversity may leave lasting physiological effects that extend beyond psychological symptoms. Through a case of a 19-year-old woman with persistent anxiety, OCD, emotional eating, and hyperandrogenic metabolic dysfunction, this article examines how neuroendocrine, metabolic, immune, nutritional, and gut-brain pathways may interact—and how a systems biology approach can complement conventional psychiatric care.

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First, Do No Harm: Managing Pediatric Klebsiella Dysbiosis Without Delaying Diagnosis

A young child with recurrent abdominal pain, bloating, constipation, sleep disturbances, and behavioral changes experienced repeated symptom improvement during integrative treatment targeting intestinal dysbiosis. This case examines the challenges of managing suspected Klebsiella-associated symptoms while navigating inconsistent treatment across two households, parental hesitation toward additional testing, and the possibility of an underlying inflammatory bowel disorder.

5-MTHF and Autism: From Nonverbal to First Words in a Pediatric Case Report

After years of speech-language and occupational therapy without functional spoken language, an 8-year-old boy with autism began vocalizing and spontaneously spoke a meaningful word approximately two weeks after starting 5-MTHF supplementation. This case examines the temporal association, potential relevance of folate-dependent pathways, and the need for further research into communication outcomes in minimally verbal autistic children.

The “Possessed” Child: Celiac Disease, PANS/PANDAS, and the Gut-Brain Connection

An 11-year-old boy with celiac disease experienced recurrent hallucinations, night terrors, aggression, and profound behavioral changes requiring multiple hospitalizations. This case explores the suspected relationship between infections, gastrointestinal disturbances, immune responses, and neuropsychiatric symptoms, including reported improvements following dietary modifications and microbiome-directed interventions.

From Constipation to Language Regression: A Longitudinal Case of Recurrent Behavioral and Communication Changes in an Autistic Child

In a child with autism, recurrent constipation consistently preceded episodes of behavioral dysregulation or loss of previously functional language. Through years of symptom tracking, laboratory assessment, and individualized treatment, this case explores two distinct clinical patterns potentially involving the gut-brain axis, with reported improvements following antifungal and antibacterial interventions.

Juvenile Idiopathic Arthritis: A Longitudinal Case of Naturopathic Care and Healing

After nearly five years without reported symptoms, a 14-year-old girl with juvenile idiopathic arthritis experienced a recurrence of joint pain, fatigue, gastrointestinal complaints, and reduced mobility. This longitudinal case examines how individualized naturopathic care, guided by the principles of healing and supported by dietary, homeopathic, and lifestyle interventions, accompanied gradual improvement in symptoms and quality of life over eight months.

Pediatric Psychosis and Catatonia: Exploring Infection-Associated Neuropsychiatric Symptoms

A previously high-functioning 10-year-old girl developed severe psychosis, catatonic features, and profound functional regression, with symptoms fluctuating for more than two years. This case examines possible infection-associated neuropsychiatric mechanisms, repeated caregiver-reported improvements during antibiotic treatment, and the patient’s eventual recovery through multidisciplinary psychiatric, medical, nutritional, and integrative care.

Babesia duncani and Pediatric Neuropsychiatric Symptoms: A Case of Delayed Diagnosis and Recovery

Following a febrile illness, a nine-year-old boy developed severe behavioral changes, anxiety, sensory disturbances, and debilitating fatigue that led to psychiatric hospitalization. This case explores the identification of Babesia duncani antibodies, a multimodal treatment approach, and the child’s subsequent improvement in neurological symptoms, emotional regulation, and daily functioning.

Pediatric ADHD and Childhood Trauma: A Trauma-Informed Naturopathic Approach

When an eight-year-old boy with previously stable ADHD developed worsening concentration, anxiety, and sleep disturbances, a trauma-informed assessment revealed a recent experience of community violence. This case explores how adverse childhood experiences can complicate pediatric ADHD presentations and how foundational naturopathic interventions targeting nutrition, sleep, and stress may complement existing behavioral and psychosocial therapies.

Archived Case Studies and Featured Content

Childhood Trauma and Mental Health: A Systems Biology Approach to Treatment-Resistant Anxiety and OCD

Childhood Trauma and Mental Health: A Systems Biology Approach to Treatment-Resistant Anxiety and OCD

Childhood adversity may leave lasting physiological effects that extend beyond psychological symptoms. Through a case of a 19-year-old woman with persistent anxiety, OCD, emotional eating, and hyperandrogenic metabolic dysfunction, this article examines how neuroendocrine, metabolic, immune, nutritional, and gut-brain pathways may interact—and how a systems biology approach can complement conventional psychiatric care.

Observation Over Interpretation: A Homeopathic Case of Phosphorus in an 8-Month-Old

Observation Over Interpretation: A Homeopathic Case of Phosphorus in an 8-Month-Old

When an 8-month-old developed sudden distress whenever his mother left the room, the choice between Phosphorus and Pulsatilla initially appeared uncertain. Through direct observation, a previously overlooked response to physical touch became the defining symptom guiding a Phosphorus prescription, followed by reported improvement within one week.

Listening Beyond Language: A Narrative Medicine Case Study for Neurodivergent Children

Listening Beyond Language: A Narrative Medicine Case Study for Neurodivergent Children

For neurodivergent children, communication extends beyond spoken language. Through a composite pediatric case, this article explores how narrative medicine, creative expression, sensory-aware facilitation, and caregiver co-regulation can support emotional communication, self-advocacy, and connection in children with autism, ADHD, and related developmental differences.

First, Do No Harm: Managing Pediatric Klebsiella Dysbiosis Without Delaying Diagnosis

First, Do No Harm: Managing Pediatric Klebsiella Dysbiosis Without Delaying Diagnosis

A young child with recurrent abdominal pain, bloating, constipation, sleep disturbances, and behavioral changes experienced repeated symptom improvement during integrative treatment targeting intestinal dysbiosis. This case examines the challenges of managing suspected Klebsiella-associated symptoms while navigating inconsistent treatment across two households, parental hesitation toward additional testing, and the possibility of an underlying inflammatory bowel disorder.

Medication-Induced Kidney Injury: Mechanisms, Risk Factors, and Prevention

Medications may account for an estimated 20% of community- and hospital-acquired acute kidney injury, with risk amplified by CKD, older age, chronic disease, dehydration, and polypharmacy. This review examines the major mechanisms of drug-induced nephrotoxicity and practical strategies for medication review, hydration, renal monitoring, and prevention.

Low Testosterone and Cardiovascular Disease: Risk Marker, Mediator, or Both?

Low testosterone is consistently associated with adverse cardiovascular outcomes, but whether it is a cause of vascular disease or a marker of underlying metabolic and inflammatory dysfunction remains unresolved. This review examines the epidemiology, vascular mechanisms, hypertension and atherosclerosis data, TRAVERSE findings, and the cardiovascular implications of TRT-induced erythrocytosis.

Cardiovascular Risk Assessment in Men: A Naturopathic Cardiology Perspective

Cardiovascular risk extends beyond LDL cholesterol and the standard lipid panel. This review explores how plaque biology, inflammation, oxidation, metabolic and hormonal health, advanced biomarkers, CGM, and cardiovascular imaging can complement established therapies to create a more individualized approach to cardiovascular risk assessment in men.

Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance

Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.

Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance

Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.

Advanced Inflammatory Breast Cancer: Complete Response with Naturopathic and Immuno-Oncology Treatment

This case follows a 44-year-old woman with inflammatory breast cancer that progressed to osseous metastatic disease and was managed through a multimodal naturopathic, immune-directed, and conventional oncology strategy. Serial imaging and molecular surveillance ultimately demonstrated complete metabolic response, zero circulating tumor cells, and repeatedly undetectable ctDNA, highlighting the potential value of adaptive, interdisciplinary integrative oncology care.

Ketogenic Diet in Metastatic Breast Cancer: An Integrative Oncology Case Study

Can a ketogenic diet play a supportive role during treatment for advanced breast cancer? This case follows a 34-year-old woman with metastatic HER2-positive breast cancer who adopted a ketogenic diet and broader lifestyle changes alongside chemotherapy and HER2-targeted therapy, while examining the evolving evidence, potential metabolic benefits, and limitations of ketogenic diets in cancer care.

Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report

Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.

Custom Publishing

Quantum Energy Effects on Cell Recovery Rates

Quantum Energy Effects on Cell Recovery Rates

Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...

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