Trending Articles
Is Heart Failure with Reduced Ejection Fraction Reversible? A Case-Based, Integrative Approach
S.A Decker Weiss, NMD, FASA, PLC A complex ischemic cardiomyopathy case exploring myocardial recovery through guideline-directed medical therapy, device support, metabolic optimization, and experimental regenerative adjuncts. Abstract This case report examines...
Strive Compounding Pharmacy Files Federal Antitrust Lawsuit Against Eli Lilly and Novo Nordisk
ARCADIA TALLMAN Strive Compounding Pharmacy has filed a federal antitrust lawsuit against Eli Lilly and Novo Nordisk, alleging a coordinated effort to suppress competition and restrict patient access to lawful compounded GLP-1 medications. The complaint, filed on...
The First Health Food Store in America Was Opened by a Naturopathic Doctor in 1896
In 1896, a 24-year-old German immigrant named Benedict Lust opened a small store in New York City. He called it a “Kneipp store,” named after Father Sebastian Kneipp, the German priest whose water cure treatments had saved Lust’s life after conventional doctors gave...
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...
Featured Article | Cardiopulmonary Medicine
Understanding Preeclampsia
How to Reduce Risk in Pregnancy and Prevent Future Cardiovascular Disease By Alexsia Priolo Introduction Pregnancy places significant physiologic stress on the cardiovascular system, prompting structural and hemodynamic changes to manage increased blood volume and...
Exclusive Content | Cardiopulmonary Medicine
Anxiety, Depression, and PTSD
Alternative and Complementary Therapy Options JOHN HAHN, DPM, ND Post-traumatic stress disorder (PTSD) is an anxiety disorder that can occur after exposure to extreme traumatic events, such as natural disasters (eg, floods, car accidents, fire) or man-made trauma (eg,...
Heart Rate Variability: The Why, What, and How of HRV and Its Importance in Private Practice – Part 2
Michael Kessler, DC, CCSP Javdat Karimov, MD, NMD LF-Sympathetic (ANS) is the predominant frequency band. This can indicate a high (epinephrine, or adrenalin) response to stress. Prolonged stress can dysregulate neurohormonal balance, such as the DHEA/cortisol ratio....
Heart Rate Variability: The Why, What, and How of HRV and Its Importance in Private Practice – Part 1
Javdat Karimov, MD, NMD Evaluating heart rate variability (HRV) in clinical practice is important. This is because HRV is a reflection of the autonomic nervous system (ANS) that controls 90% of the body’s functions. The 2 branches of the ANS consist of the...
Spirituality in Clinical Practice
Deborah Frances, RN, ND Tolle Totum It is always the Spirits who heal. Many times the Spirit directed me what to do for people. I depended on prayer a lot. I am only a passageway for Spirit. (Black Star, Comanche medicine woman; personal interview, Medford, Oregon,...
Common Arrhythmias Encountered in Primary Practice
A Naturopathic Perspective Emily A. Kane, ND, LAc There’s a saying among cardiologists that rate is easier to control than rhythm. One of the problems with arrhythmias is that the anti-arrhythmic drugs are typically rife with dangerous side effects. The best known,...
Managing Essential Hypertension
A Review of Evidence-Based Strategies Elaine Lewis, HBSc, ND Monique Aucoin, BMSc, ND Kieran Cooley, Bsc, ND, MSC CAND Primary hypertension (HTN) is one of the most prevalent and preventable diseases facing North America. The disorder is linked to premature mortality,...
The Role of Advanced Glycation End Products in CVD
Docere Gaetano Morello, ND Glycation is a nonenzymatic reaction between sugars, such as glucose and fructose, and biological proteins, resulting in the production of advanced glycation end products (AGEs). These compounds accumulate in the body throughout one’s life...
Karoshi: Death by Overwork
Catherine Darley, ND In Japan, karoshi refers to suicides of employees after a period of overwork and work stress. Here in America, many people are working to the extent that their health is damaged and disease states manifest, although not yet to the extent that we...
Archived Case Studies and Featured Content
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
RAZI BERRY Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
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Featured News
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
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