Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...

Trending Articles
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Featured Article | Insomnia/Sleep Medicine
Insomnia Could Lead to Cognitive Decline in Later LIfe
From University of Helsinki The Helsinki Health Study at the University of Helsinki investigated the development of insomnia symptoms in midlife and their effects on memory, learning ability and concentration after retirement. The follow-up period was 15-17 years....
Exclusive Content | Insomnia/Sleep Medicine
Sleep: The Emerging Science & Its Clinical Implications
Krista Anderson-Ross, ND Tolle Totum Sleep is a criminal waste of time, inherited from our cave days. (Thomas Edison) While it’s easy to believe that sleep deprivation is a manifestation of the modern world and the effects of increasingly occupied opposable thumbs,...
A Nightmare of a Case: Homeopathic Approaches to Sleep Issues in Children
Anke Zimmermann, BSc, ND, FCAH Sleep issues, including nightmares and sleep-walking, are a common problem in children. Sleep and dream symptoms are generally a clear expression of the vital force and can often lead to wonderfully accurate prescriptions that can...
Teen Sleep: Getting It Right
Catherine Darley, ND Remember being a teenager, staying up late, and sleeping till noon on the weekends? Most likely you have teen patients in your clinic who are experiencing the same sleep pattern. Unfortunately, because school hours are not aligned with teen...
Optimizing Sleep: A Multi-Pronged Approach
Mark Woodall, MS, ND The therapeutic order, as elaborated by Drs Jared Zeff and Pamela Snider, begins with, “Establish the conditions for health.”1 Optimizing sleep quality and duration is therefore one of the most essential first steps. The aim of this article is to...
The Cytokine Connection to Insomnia
Mary Bove, ND Excerpts from lecture notes for presentation at upcoming Southwest Conference on Botanical Medicine, April 10 – 12, 2015 at SCNM in Tempe, Arizona www.botanicalmedicine.org Can inflammation and immune dysfunction play a major role in insomnia? Research...
Passionflower and Lemon Balm
Their Roles in Sleep Mandana Edalati, ND Most people are familiar with the occasional tossing and turning in bed, but when this occurs on a chronic basis, it becomes more than just a nuisance. Sleep affects every cell, organ, and system in the body. It affects...
Melatonin
The Miracle Hormone? Timothy Schwaiger, ND For many years the hormone melatonin has been used for a variety of conditions. Although melatonin has primarily been used for the treatment of insomnia, many physicians and researchers have focused on other beneficial...
Depression — Part 2
Part 2 of 2 David Arneson, ND Many vitamins and minerals serve as cofactors and coenzymes for the production of neurotransmitters from amino acids. Our mainstay for treating depression and other mental health issues has always been intravenous (IV) nutrition and...
Archived Case Studies and Featured Content
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Why Naturopathic Doctors Recommend Different Treatments: Understanding Individualized Care in Naturopathic Medicine
Dr. Eli Camp, ND How vitalist principles, clinical judgment, and therapeutic order shape personalized treatment strategies for the same diagnosis. Abstract This article explains why two naturopathic doctors may recommend different treatments for the same...
Curcumin Benefits and Bioavailability: Separating Mechanism from Marketing
Devin Miles, ND Abstract This article reviews the clinical evidence supporting curcumin’s role in inflammation, joint health, and oxidative stress, including comparisons with conventional therapies such as NSAIDs. It also examines the challenges of curcumin...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Why Naturopathic Doctors Recommend Different Treatments: Understanding Individualized Care in Naturopathic Medicine
Dr. Eli Camp, ND How vitalist principles, clinical judgment, and therapeutic order shape personalized treatment strategies for the same diagnosis. Abstract This article explains why two naturopathic doctors may recommend different treatments for the same...
Curcumin Benefits and Bioavailability: Separating Mechanism from Marketing
Devin Miles, ND Abstract This article reviews the clinical evidence supporting curcumin’s role in inflammation, joint health, and oxidative stress, including comparisons with conventional therapies such as NSAIDs. It also examines the challenges of curcumin...
GLP-1 Agonists and Persistent Organic Pollutants (POPs): Lipophilic Toxin Mobilization During Rapid Fat Loss
Michael E. McEvoy, Kareem Kandil, ND This article examines the potential for rapid fat loss induced by GLP-1 agonist therapies to mobilize stored lipophilic persistent organic pollutants (POPs) from adipose tissue into circulation. It reviews evidence from weight loss...
Paris to Host Landmark Global Gathering for Naturopathic Medicine in 2026
10th Integrative & Naturopathic Medicine World Congress & Expo Returns for Its Milestone 10th Edition Paris — July 10–11, 2026 — The global stage is set for one of the most influential events in integrative healthcare as the 10th Integrative &...
Restorative Formulations Launches the NeuroSynergy Clinical Series
Four professional-grade formulas targeting distinct neurochemical pathways to support mood, stress resilience, and cognitive function are now available exclusively to licensed practitioners. Montpelier, VT, March 27, 2026 — Restorative Formulations has released the...
Quantum Energy Effects on Cell Recovery Rates
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human...
Naturopathic Medicine Institute Announces Vital Gathering 2026: Clinical Training in Therapeutic Touch and Vitalist Practice
TEMPE, AZ / March 25, 2026 The Naturopathic Medicine Institute (NMI) announces Vital Gathering 2026, its annual continuing education conference for naturopathic physicians and students, taking place April 24–26, 2026, at Sonoran University of Health Sciences....
Custom Publishing
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Featured News
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Strive Compounding Pharmacy Files Federal Antitrust Lawsuit Against Eli Lilly and Novo Nordisk
ARCADIA TALLMAN Strive Compounding Pharmacy has filed a federal antitrust lawsuit against Eli Lilly and Novo Nordisk, alleging a coordinated effort to suppress competition and restrict patient access to lawful compounded GLP-1 medications. The complaint, filed on...






