Night sky photos activated all 6 dimensions of awe, increased positive emotion, and restored mental focus in under 3 minutes. People Who Looked at the Night Sky Felt Vastly Different Within Minutes Photographs of deep space and starry night skies activated all 6...
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Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
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Endurance Products Company (EPC), is the exclusive marketing affiliate of Innovite Inc, manufacturer of select nutritional supplements which feature the proprietary wax-matrix, controlled-release technology. Endur-acin® is our best-selling, extended-release niacin,...
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Archived Case Studies and Featured Content
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Dr. Vy Simeles, ND, Restorative Health Clinic Abstract This case report details the recovery of a 22-year-old...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
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Featured News
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...





