Variability is crucially important for learning new skills. Consider learning how to serve in tennis. Should you always practice serving from the exact same location on the court, aiming at exactly the same spot? Although practising in more variable conditions will be...
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Table of Contents | 2022 | May
Why I became a Naturopathic Doctor
Holly Lucille, ND, RN I grew up in the Midwest, the daughter of two pharmacists, and was very well versed in the Western medical approach: “You don’t feel well? Here, take this pill.” Even at a very young age I was troubled by this approach to health and always...
Notes from the Field- March 2022
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Take a Break from Social Media to Improve Mental Health
From University of Bath Asking people to stop using social media for just one week could lead to significant improvements in their wellbeing, depression and anxiety and could, in the future, be recommended as a way to help people manage their mental health say the...
A Mechanism for Preventing Build up of Toxic Proteins Leading to Dementia 
From University of Cambridge It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in...
Hormone Regulator of Low-Protein Diet Benefits
From Pennington Biomedical Research Center A single hormone appears to coordinate the lifespan extension produced by a low-protein diet. A new study from Pennington Biomedical Research Center, published in the journal Nature Communications, found that reducing the...
Gut Microbiome Can Tell Us About Concussion Status
From Houston Methodist A recently published study by Houston Methodist scientists suggests telltale signs of concussions might be found in the gut. By taking blood, stool and saliva samples from 33 Rice University football players, the researchers were able to examine...
Increased Chemical Exposure in Pregnant Women
From University of California - San Francisco A national study that enrolled a highly diverse group of pregnant women over 12 years found rising exposure to chemicals from plastics and pesticides that may be harmful to development. Many of the chemicals that the women...
Botanicals for Graves’ Disease
Botanicals for Graves’ Disease An Herbal Case Study BRIAN KEENAN, ND, LAC During my early years as a clinical intern I was tasked with seeing a new patient who was considered difficult. She was irritable, untrusting, and many in the clinic had...
Melatonin & Glucose Homeostasis
A Complex Relationship GINA BROWN RICK BHIM, ND, CCNM Type 2 diabetes (T2DM) is a global health concern, affecting over 462 million individuals worldwide.1 It is a widely common condition in clinical practice and is a significant burden on the healthcare...
Linking Heart Disease in People with Diabetes Using Gene Mapping
From American Heart Association A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed...
Exploring Electrical Synapses in the Brain
From Max-Planck-Gesellschaft They are part of the brain of almost every animal species, yet they remain usually invisible even under the electron microscope. "Electrical synapses are like the dark matter of the brain," says Alexander Borst, director at the MPI for...
Vis Medicatrix Naturae Quercetin, Vitamin C, and Beyond
Helping Patients Through the Allergy Season HOLLY LUCILLE, ND, RN Abstract Seasonal allergies and chronic respiratory conditions often involve immune overreaction, leading to histamine release, inflammation, and persistent discomfort. This article reviews...
How Political Orientation Shapes How We Perceive Others
From University of Toronto A new U of T Scarborough study finds that liberals and conservatives differ in how they perceive dominance in women, which may influence their likelihood to vote them into political office. "We found that conservatives and liberals read...
Archived Case Studies and Featured Content
How to Get the Most from Your Cancer Doctor Visits: A Guide for Patients and Survivors
Cancer care can be complex and overwhelming, but preparation can make medical appointments more productive and less stressful. This practical checklist offers 18 strategies to help patients communicate effectively with providers, organize their care, explore treatment options, and build a collaborative medical “dream team.”
Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report
Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Missing Question: How Occupational Heavy Metal Exposure Contributed to Severe Testosterone Deficiency in a Young Male
Glenn B. Gero, ND, DSc, M.E.S., R.H. (AHG), EndoANP Kareem Kandil, MD, ND A case study demonstrating how a simple occupational history uncovered chronic heavy metal exposure as a likely contributor to severe hypogonadism, highlighting the critical role of...
Reduction of Thyroid Antibodies with Tirzepatide in Hashimoto’s Thyroiditis: A Metabolic-Immune Case Report
Dr. Valerie Gettings, NMD A case report exploring how low-dose tirzepatide improved insulin resistance, thyroid function, and thyroid autoantibody levels in a patient with Hashimoto’s thyroiditis, highlighting the emerging role of metabolic therapies in...
16-Hydroxyestrone, Enterohepatic Recirculation, and Dysmenorrhea: Personalizing Hormone Care Through Estrogen Metabolite Testing
Dr. Liz Bartman, ND A case-based exploration of how urinary estrogen metabolites can reveal hidden patterns of estrogen recirculation, gut-liver dysfunction, and hormone clearance that contribute to menstrual pain and heavy bleeding. This case report examines a...
Nigella sativa: The Ancient Herbal Remedy Supporting Thyroid Resilience in Hashimoto’s Thyroiditis
Lillea Hartwell, ND A comprehensive review of Nigella sativa seed oil, its active constituents, safety profile, pharmacology, and emerging clinical evidence for supporting immune regulation and thyroid function in Hashimoto’s thyroiditis. This monograph reviews...
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
The Silent Male Infertility Epidemic: How Men Can Protect & Restore Their Fertility
Dr. Samuel Madeira, N.M.D. Infertility affects about 180 million people worldwide and at least 15% of couples in the United States alone. The far-too-often overlooked factor in fertility medicine today is the male contribution, accounting for the cause of 30-50% of...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
From PCOS to PMOS: What the Name Change Means for Your Practice
Dr. Jaclyn Smeaton, ND A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...
Custom Publishing
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow within integrative and naturopathic...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Featured News
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...
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