A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...

Trending Articles
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
Featured Article | Mind/Body
Complex Chronic Illnesses
Opportunities for Mind/Body Reintegration THALIA HALE, ND One of my biggest “never say never” moments was in naturopathic medical school over 10 years ago, when I said that I would never treat Lyme disease. With my limited knowledge, I could not get behind...
Exclusive Content | Mind/Body
Karoshi: Death by Overwork
Catherine Darley, ND In Japan, karoshi refers to suicides of employees after a period of overwork and work stress. Here in America, many people are working to the extent that their health is damaged and disease states manifest, although not yet to the extent that we...
Depression — Part 2
Part 2 of 2 David Arneson, ND Many vitamins and minerals serve as cofactors and coenzymes for the production of neurotransmitters from amino acids. Our mainstay for treating depression and other mental health issues has always been intravenous (IV) nutrition and...
Anxiety and Depression: A Materia Medica Review
Jillian Stansbury, ND By numerous accounts, a large percentage of the US population is using antidepressant and anxiolytic medications. This may say a lot about the condition of the human heart and soul. A 2005 survey1 done by Kaiser Permanente reported that the use...
Insomnia: Review of Nutritional Interventions
Jonathan E. Prousky, ND, MSc Biopsychosocial Context Insomnia, as defined by the American Academy of Sleep Medicine,1 is unsatisfactory sleep that impacts daytime functioning. The Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) describes the...
Depression and Sleep Quality
Peter Bongiorno, ND, LAc Regular, quality sleep is of paramount importance to good mood and good health. Evaluating and solving sleep issues address a pertinent underlying cause in the pathogenesis of depression and deserve strong attention by the physician....
Depression: Protocols for Repairing Biochemical and Neurochemical Processes
David Arneson, ND Depression is defined in Stedman’s Medical Dictionary 25th Edition1 as a reduction of the level of functioning. It is also defined as a sinking of spirits so as to constitute a clinically discernible condition. Endogenous depression is further...
Management of Opioid-Induced Constipation
Tolle Causam Gaia Mather, ND Constipation is a problem that will affect nearly every patient at some time in their lives. According to Goodheart and Leavitt,1 functional constipation affects 12% to 19% of the American population. Whether due to a transient change in...
The Current Healing Crisis—Part 2
Why Anthroposophically Enhanced Medicine? Robert B. Kellum, ND, PhD, MSOM/LAc, LMT Click to Read Part - 1 Click to Read Part - 2 Click to Read Part - 3 Click to Read Part - 4 Finding the Causative Factors of Illness In his discussion of “therapeutic order” in...
Archived Case Studies and Featured Content
Fifteen Questions to Get Patient Commitment
Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
By Lina Mockus, ND How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and what integrative care can do about it. This article explores the shared metabolic, inflammatory, and microbiome-driven...
Resolution of Exercise-Induced Asthma with Individualized Homeopathic Treatment: A Case Report
Dr. Michael Knapp, ND, DHANP A case demonstrating sustained remission of exercise-induced asthma, allergic oropharyngeal symptoms, and recurrent respiratory infections in an adolescent following constitutional homeopathic care. This case report describes the...
Arterial Plaque Regression: A Case-Based, Integrative Approach to Cardiovascular Risk Reduction
Dr. Stephen Parcell, ND A preventive cardiology case demonstrates how advanced imaging, aggressive lipid optimization, and integrative therapies can reduce coronary plaque burden in a high-risk patient. This case report examines the regression of coronary...
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
Influenza and COVID Vaccines Disrupt Hypothalamic-Pituitary Axis
Vaccine Immune Response Interferes with Female Reproductive Cycle 2025 JAMA Study Reveals Direct Evidence of Neuroendocrine Effects The 2025 study published in JAMA Network Open provides clear evidence that vaccines affect brain regulatory systems. Researchers...
Midlife Movement Determines Brain Aging
Midlife is the time to move more to protect your brain. By your 40s and 50s, measurable changes in brain structure have already begun. Gray matter volume starts to decline. White matter pathways lose integrity. Amyloid plaques, protein deposits linked to Alzheimer’s...
The Integrative Management of Psoriasis
A Case Study in Homeopathy, Nutrition, and Lifestyle Medicine A comprehensive, patient-centered approach to managing psoriasis by addressing root causes through homeopathy, gut health, and metabolic balance. By Marisa Kassimir, ND Introduction and Case Presentation...
Plastic Chemical Exposure Linked to Over 356,000 Cardiovascular Deaths in 2018
DEHP in Plastics Promotes Inflammation and Arterial Damage Leading to Heart Disease Millions handle plastic products daily, including food containers, medical tubing, and water bottles. These common items often contain di-2-ethylhexyl phthalate (DEHP), a chemical used...
Optimizing Healthy Aging for Older Adults
Insights from a Case Series Using a Novel Supplement Regimen Jen Palmer, ND; Joseph M. Keenan, MD Dietary supplements can provide older adults a therapeutic option for maintaining optimal health without relying on prescription drugs. This article summarizes key...
Selective Toxicity of Vitamin C to Cancer Cells
A vital aspect of high-dose vitamin C therapy is its selective toxicity towards cancer cells. Cancer cells are uniquely susceptible due to their inherently higher levels of oxidative stress and reactive iron. At therapeutic concentrations, intravenous vitamin C...
Gut Bacteria Directly Trigger Chronic Pain in Fibromyalgia
Gut microbes from patients rapidly activate immune responses and nerve changes that drive lasting, unexplained pain. Gut Microbes Influence Chronic Pain and Immunity Fibromyalgia is a chronic pain condition characterized by widespread pain throughout the body, often...
Healthy Gut, Healthy Blood: Gut Health Shown to Prevent Leukemia
Naturopathic medicine has long emphasized digestive health as foundational to robust immune function. Early naturopathic physicians drew inspiration from pioneering microbiologist Elie Metchnikoff, who proposed in the early 1900s that beneficial gut bacteria are...
Air and Light Pollution Raise Childhood Thyroid Cancer Risk by 7–25%
Early-Life Exposure from Pregnancy to Age One Impacts Teens' Health Early exposure to air pollution and artificial electric lighting increases children's thyroid cancer risk by measurable amounts. Children exposed from pregnancy through their first year experience a...
Optimizing Healthy Aging for Older Adults
Insights from a Case Series Using a Novel Supplement Regimen Jen Palmer, ND; Joseph M. Keenan, MD Dietary supplements can provide older adults a therapeutic option for maintaining optimal health without relying on prescription drugs. This article summarizes key...
Selective Toxicity of Vitamin C to Cancer Cells
A vital aspect of high-dose vitamin C therapy is its selective toxicity towards cancer cells. Cancer cells are uniquely susceptible due to their inherently higher levels of oxidative stress and reactive iron. At therapeutic concentrations, intravenous vitamin C...
Gut Bacteria Directly Trigger Chronic Pain in Fibromyalgia
Gut microbes from patients rapidly activate immune responses and nerve changes that drive lasting, unexplained pain. Gut Microbes Influence Chronic Pain and Immunity Fibromyalgia is a chronic pain condition characterized by widespread pain throughout the body, often...
Healthy Gut, Healthy Blood: Gut Health Shown to Prevent Leukemia
Naturopathic medicine has long emphasized digestive health as foundational to robust immune function. Early naturopathic physicians drew inspiration from pioneering microbiologist Elie Metchnikoff, who proposed in the early 1900s that beneficial gut bacteria are...
Air and Light Pollution Raise Childhood Thyroid Cancer Risk by 7–25%
Early-Life Exposure from Pregnancy to Age One Impacts Teens' Health Early exposure to air pollution and artificial electric lighting increases children's thyroid cancer risk by measurable amounts. Children exposed from pregnancy through their first year experience a...
Pediatric Mattress Emissions Linked to Hormone Disruption, Cancer, and Neurodevelopmental Harm During Sleep
Toxic chemicals in children’s mattresses are released by body heat and weight, directly into the breathing zone during sleep. For infants and toddlers, chemical exposure during sleep can disrupt hormones, interfere with neurological development, impair organ function,...
CT Radiation Risks: Research Shows 103,000 New Cancer Cases Annually from Medical Imaging
Medical Radiation Now Accounts for 5% of All Cancer Diagnoses, Equal to Alcohol and Obesity Computed tomography (CT) scans performed in the United States will cause approximately 103,000 future cancers, accounting for a staggering 5% of all cancer diagnoses annually....
AI Alone Is Not Enough for Cancer Care, Say Researchers
Clinicians Warn Against Relying on AI Without Biological Insight or Clinical Judgment Artificial intelligence tools are increasingly used to forecast cancer treatment outcomes, but physicians warn that these models fail without biological grounding and clinical...
From Kitty Litter to Cortical Recovery
A Naturopathic Case Study on Reversing CIRS-Induced Brain Atrophy Eric Dorninger ND, LAc This case study examines a 39-year-old male with severe neurological symptoms linked to Chronic Inflammatory Response Syndrome (CIRS) triggered by endotoxin exposure from a kitty...
From Toxicology to Clinical Application:
Applying Primary Source Research to Homeopathic Practice Jamie Oskin, ND, DTBRm, DHANP In a previous NDNR editorial, I gave a review of a groundbreaking new conference at Sonoran University in Tempe, Arizona, that was a collaborative project of the American Institute...
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Featured News
Healthy Gut, Healthy Blood: Gut Health Shown to Prevent Leukemia
Naturopathic medicine has long emphasized digestive health as foundational to robust immune function. Early naturopathic physicians drew inspiration from pioneering microbiologist Elie Metchnikoff, who proposed in the early 1900s that beneficial gut bacteria are...
Air and Light Pollution Raise Childhood Thyroid Cancer Risk by 7–25%
Early-Life Exposure from Pregnancy to Age One Impacts Teens' Health Early exposure to air pollution and artificial electric lighting increases children's thyroid cancer risk by measurable amounts. Children exposed from pregnancy through their first year experience a...



