Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...

Trending Articles
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Featured Article | Oncology
Medicinal Orchid Demonstrates Tissue Healing for Cancer Patients
Iron-Clad Orchid (Dendrobium officinale, Tiepi Shihu) Improves Salivary Gland Function and Oral Microbiota in Nasopharyngeal Cancer Patients Undergoing Radiotherapy Dendrobium officinale, also known as Tiepi Shihu or iron-clad orchid, has been integral to traditional...
Exclusive Content | Oncology
Cancer-Related Pain: Can Natural Therapies Be Effective Adjuncts?
Heather Paulson, ND, FABNO Tolle Causam Cancer-related pain is frequently experienced by cancer patients and can negatively both affect quality of life and functional status. According to the National Cancer Institute, pain occurs in 20% to 50% of patients with...
Mind-Body Medicine: The Essence of Ayurveda
Virender Sodhi, ND, MD (Ayurved) Docere Ayurveda - The Ancient Medicine Mind-body medicine is a relatively modern medical approach in the United States and Western medicine traditions. Starting in the Renaissance and Enlightenment ages, philosophers (who were often...
Addressing a Deeper Etiology: A Follow-up on ACEs
Paul Epstein, ND Sonia Malani Tolle Causam Practical Integration of the Mind, Body, and Spirit Students come to naturopathic medical school with an empty toolkit and a vast amount of curiosity. As students, we aspire to obtain a spectrum of healing principles to take...
Immune Modulator for Autoimmune Disease?
Carrie Decker, ND Vis Medicatrix Naturae Active Hexose Correlated Compound Although the naming of the phenomenon of autoimmune disease is simple and reflects a self-triggered immune response, factors leading to the development of this state are complex and many. The...
Tracking Cancer Through Blood Biopsy
Beginning with Blood Biopsies An NPR segment recently addressed the bright future of blood biopsies for tracking cancer and determining treatment, without the use of surgical tissue biopsy. Broad Institute of MIT and Harvard is one of the world’s leading centers of...
Cancer Cachexia in the Elderly: The Role of Nutritional Supplementation
Tolle Totum Sukriti Bhardwaj, BHSc Monique Aucoin, BMSc, ND Within the elderly patient population, cancer is a growing concern. In 2013, there were an estimated 841 million elderly cancer patients (ECPs) worldwide, and this figure is projected to reach 2 billion by...
Acupressure Reduced Fatigue in Breast Cancer Survivors
According to a study out of the University of Michigan Health System and published in JAMA Oncology, acupressure helped reduce persistent fatigue in women who had been treated for breast cancer. Fatigue is one of the most common long-term effects of breast cancer...
AANP Launches Cancer Care Program
Creating Integrative Cancer Teams: Learning from those who Make it Work Program Description Integrative, interdisciplinary medicine is the future of healthcare. Optimal health is achieved through personalized health care that addresses the cause of the illness and the...
Archived Case Studies and Featured Content
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Naturopathic Dementia Prevention: Clinical Strategies for Neurodegeneration
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
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Featured News
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...





