An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...

Trending Articles
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
Dr. Vy Simeles, ND, Restorative Health Clinic A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Abstract This case report details the recovery of a...
Infection, Neuroinflammation, and Immune Dysregulation: The Clinical Overlap of Lyme Disease and PANS/PANDAS and a Path to Healing
Understanding the clinical overlap between vector-borne infections and pediatric acute-onset neuropsychiatric syndromes—and a systems-based integrative path to healing. Dr. Myriah Hinchey, ND, FMAPS Abstract This article examines the biological overlap between Lyme...
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Featured Article | Oncology
Diet Change Slows Prostate Cancer Growth in Clinical Trial
39% Difference in Cancer Cell Growth Between Diet Groups A targeted diet low in omega-6 and high in omega-3 fatty acids, plus fish oil supplements, significantly slowed prostate cancer cell growth in men with early-stage disease. The UCLA-led clinical trial...
Exclusive Content | Oncology
Breast Cancer Prevention: Considerations for High-Risk Women
Lise Alschuler, ND, FABNO As a breast cancer survivor and a doctor who often treats high-risk women, this is a subject to which I pay very close attention. Because of the prevalence of breast cancer, regardless of your clinical focus, it’s likely that you have had a...
Assessing Prostate Cancer Four Pragmatic Questions to Consider
Phranq D. Tamburri, NMD When seeing a patient for prostate cancer (CaP), a physician often encounters a quandary when determining how to explain the patient’s risk to him. After all, it is a known fact that the majority of men who are diagnosed with prostate cancer...
Physical Activity in Children & Youth: Benefits, Barriers, and Recommendations
Leslie Solomonian, ND Benefits of Physical Activity Physical activity has wide-reaching benefits for children, including improving body composition, academic performance, self-esteem, and bone mass. Physical activity in childhood predicts physical activity in...
Move Over, MTHFR: Time to Look at COMT
Jared M. Skowron, ND After giving methylfolate to hundreds of patients, I noticed some of them responded with aggression, anxiety, anger, and irritability. When they stopped their supplementation, the side effects resolved. While many practitioners adjust dose, add...
Voices of Naturopathic Research: Interviews with NCNM, Bastyr, SCNM, & NUHS Research Faculty
Mark Swanson, ND What are 5 interesting things about the naturopathic academic research departments? I wanted to find out, so I invited the Research Faculty Chairs from National College of Naturopathic Medicine (NCNM), Bastyr University, National University of Health...
Optimizing the HPA Axis
Lise Alschuler, ND For many patients, chronic stress is a fact of modern life. Yet, while most clinicians are keenly aware that stress can play a major role in the development of disease, it’s also important to be familiar with how the underlying stress response...
Becoming What We Fight
Specialty Boards in American Naturopathic Medical Education David J. Schleich, PhD These days Elsevier publishes an annual guide to medical specialties of US biomedicine. Unless one is aware of the proliferation of such groups since the 1930s, the list is astonishing...
Glutamine: A Solution for Chemotherapy-Induced Peripheral Neuropathy?
Malea MacOdrum, NCNM Loch chandler, ND, Msom, lac Student Scholarship – Honorable Mention Case Study Peripheral neuropathy is a serious and often treatment-limiting side effect of several common cancer chemotherapeutics. Aside from impacting activities of daily living...
Archived Case Studies and Featured Content
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Akkermansia muciniphila: Clinical Insights on a Next-Generation Probiotic
Sara Love, ND A clinician’s guide to when—and when not—to use A. muciniphila: evidence for gut-barrier support, metabolic and immune effects, pasteurized vs live formulations, and patient selection. Abstract Akkermansia muciniphila is an emerging “next-generation”...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a...
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Featured News
New Research Validates Naturopathic View of Neurological Disease
Golf course herbicides cause dopaminergic neuron death and initiate Parkinson's disease Decades of naturopathic medicine casework on pesticide-linked neurological decline are now confirmed by population-based data showing increased Parkinson's risk near golf courses....
NDNR Welcomes Dr. Kareem Kandil, MD, ND as New Medical Director
Scottsdale, Arizona – May 13, 2025 – Naturopathic Doctor News & Review (NDNR) proudly welcomes Dr. Kareem Kandil, MD, ND, as its incoming Medical Director. Dr. Kandil brings an exceptional combination of expertise spanning clinical practice, academic instruction,...




