Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
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Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
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Featured Article | Oncology
Diet Change Slows Prostate Cancer Growth in Clinical Trial
39% Difference in Cancer Cell Growth Between Diet Groups A targeted diet low in omega-6 and high in omega-3 fatty acids, plus fish oil supplements, significantly slowed prostate cancer cell growth in men with early-stage disease. The UCLA-led clinical trial...
Exclusive Content | Oncology
Breast Cancer Prevention: Considerations for High-Risk Women
Lise Alschuler, ND, FABNO As a breast cancer survivor and a doctor who often treats high-risk women, this is a subject to which I pay very close attention. Because of the prevalence of breast cancer, regardless of your clinical focus, it’s likely that you have had a...
Assessing Prostate Cancer Four Pragmatic Questions to Consider
Phranq D. Tamburri, NMD When seeing a patient for prostate cancer (CaP), a physician often encounters a quandary when determining how to explain the patient’s risk to him. After all, it is a known fact that the majority of men who are diagnosed with prostate cancer...
Physical Activity in Children & Youth: Benefits, Barriers, and Recommendations
Leslie Solomonian, ND Benefits of Physical Activity Physical activity has wide-reaching benefits for children, including improving body composition, academic performance, self-esteem, and bone mass. Physical activity in childhood predicts physical activity in...
Move Over, MTHFR: Time to Look at COMT
Jared M. Skowron, ND After giving methylfolate to hundreds of patients, I noticed some of them responded with aggression, anxiety, anger, and irritability. When they stopped their supplementation, the side effects resolved. While many practitioners adjust dose, add...
Voices of Naturopathic Research: Interviews with NCNM, Bastyr, SCNM, & NUHS Research Faculty
Mark Swanson, ND What are 5 interesting things about the naturopathic academic research departments? I wanted to find out, so I invited the Research Faculty Chairs from National College of Naturopathic Medicine (NCNM), Bastyr University, National University of Health...
Optimizing the HPA Axis
Lise Alschuler, ND For many patients, chronic stress is a fact of modern life. Yet, while most clinicians are keenly aware that stress can play a major role in the development of disease, it’s also important to be familiar with how the underlying stress response...
Becoming What We Fight
Specialty Boards in American Naturopathic Medical Education David J. Schleich, PhD These days Elsevier publishes an annual guide to medical specialties of US biomedicine. Unless one is aware of the proliferation of such groups since the 1930s, the list is astonishing...
Glutamine: A Solution for Chemotherapy-Induced Peripheral Neuropathy?
Malea MacOdrum, NCNM Loch chandler, ND, Msom, lac Student Scholarship – Honorable Mention Case Study Peripheral neuropathy is a serious and often treatment-limiting side effect of several common cancer chemotherapeutics. Aside from impacting activities of daily living...
Archived Case Studies and Featured Content
Approaching Idiopathic Neuropathy: A Naturopathic Strategy Beyond Diabetes
A clinical overview of diagnosing and treating non-diabetic neuropathy through root-cause evaluation, including autoimmunity, infections, biotoxin exposure, and small fiber nerve pathology. Dr. Jason Porter, NMD Abstract This article explores a naturopathic framework...
Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body
An in-depth exploration of how somatic awareness, interoception, and relational neuroscience can support nervous system regulation, authenticity, and healing in clinical practice. Allison Creech, M.Ed., ND Abstract This article examines mind-body medicine as a...
Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Dr. Nicole Roberts, ND Abstract In this case report, we see a 48-year-old female, over...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Dr. Leslie Solomonian, ND Abstract This article examines rising...
Anticipatory Anxiety: A Case Study in Individualized Homeopathic Care
Michael Knapp, ND, DHANP A compelling case of chronic anxiety, compulsive behavior, and digestive distress resolved through precise homeopathic prescribing guided by pattern recognition and physical symptom correlation. Abstract A 25-year-old male with lifelong...
June 2025 Cont. References
Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...
A Root-Cause Approach to Menopausal Insomnia and Brain Dysfunction: A Case Study
Discover how a 48-year-old woman overcame chronic insomnia, fatigue, and cognitive decline during menopause through a personalized, brain-first, hormone-balancing approach. Stephanie Yang, ND Abstract Menopause is not only a hormonal milestone but also a neurological...
Seeing Beyond the Mirror: How Psilocybin Could Transform Body Dysmorphic Disorder Treatment
Georgiana Cullen-Kerney, ND, LAc Emerging research reveals that psilocybin, the active compound in magic mushrooms, may offer a groundbreaking approach to treating Body Dysmorphic Disorder (BDD) by enhancing cognitive flexibility and reducing obsessive thought...
Nighttime Urination and Sleep Apnea: The Overlooked Connection
Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...
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Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Flavor as Medicine: The Science of Taste is Key to Better Health
Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...
Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle
Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Depression Appears 8 Years Before Pain Begins
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...
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Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Flavor as Medicine: The Science of Taste is Key to Better Health
Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...
Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle
Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Depression Appears 8 Years Before Pain Begins
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...
Resolving Acne Vulgaris Through Gut and Hormone Support: A Case Study
By Chelsea Smithback, ND Introduction Acne vulgaris is a very common skin condition, with a prevalence rate ranging from 25% to 95% among adolescents. It is more common in males than females. Acne can persist into adulthood or have a delayed onset during this stage of...
Targeting Menopausal Acne: Hormone Balancing and Skin Barrier Support in Practice
Aarti Patel, ND ABSTRACT This case study explores menopausal acne in a 55-year-old female with severe skin barrier damage from a history of using medical-grade prescription, as well as over-the-counter acne topicals, along with a more recent history of supplementing...
Mechanisms of Aging and Neurodegeneration
Exploring Thiamine Deficiency, Catecholamine Toxicity, and Angiotensin II Quinn Rivet, ND Exploring how thiamine deficiency, catecholamine-induced neurotoxicity, and Angiotensin II contribute to neurodegeneration and aging in the brain. Introduction This paper aims to...
Breaking the Cycle: Understanding PCOS-Related Skin Manifestations
Pathophysiology, Clinical Implications, and Evidence-Based Naturopathic Interventions Galina Mironova, ND Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder with systemic effects, including significant dermatologic manifestations. Acne, hirsutism,...
New Research Validates Naturopathic View of Neurological Disease
Golf course herbicides cause dopaminergic neuron death and initiate Parkinson's disease Decades of naturopathic medicine casework on pesticide-linked neurological decline are now confirmed by population-based data showing increased Parkinson's risk near golf courses....
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Featured News
Resveratrol–Copper Combination Suppresses Glioblastoma Growth and Restores Immune Function
Tumor proliferation suppressed, immune function restored, and harmful DNA cleared with no adverse reactions reported Glioblastoma multiforme (GBM) remains among the deadliest primary brain cancers, notoriously resistant to current treatments. A 2025 pilot clinical...
Pharmacists Continue to Dispense Antidepressants Despite Hesitation, Study Finds
Pharmacists Fear Discussing Antidepressant Risks, Leaving Patients Uninformed and Overmedicated The Serotonin Theory Has Been Debunked For decades, depression treatments rested on a simple theory: low serotonin caused depression. An expansive, rigorous analysis of...








