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Diet Change Slows Prostate Cancer Growth in Clinical Trial

39% Difference in Cancer Cell Growth Between Diet Groups

A targeted diet low in omega-6 and high in omega-3 fatty acids, plus fish oil supplements, significantly slowed prostate cancer cell growth in men with early-stage disease. The UCLA-led clinical trial demonstrated a 15% decrease in cancer cell proliferation compared to a 24% increase in untreated patients.

The CAPFISH-3 trial studied 100 men with low-risk prostate cancer for one year. Researchers tracked cancer cell growth through Ki-67 index measurements from precise image-guided biopsies. The intervention group received personalized nutritional counseling focused on reducing processed foods and increasing omega-3-rich fish consumption.

Patients followed specific dietary changes, including switching to olive oil dressings, reducing fried foods, avoiding processed snacks, and eating more salmon. The structured nutritional program gave patients active control over their cancer management through sustainable lifestyle changes.

This research opens new possibilities for using dietary intervention as part of prostate cancer treatment. Future studies will explore optimal omega fatty acid ratios and potential benefits for patients with more advanced diseases.

Reference

Aronson WJ, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. Journal of Clinical Oncology. 2024.

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