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Table of Contents | 2021
Immune Function & Competence: Gut Microbial Influences
MICHELLE MADDUX, ND Abstract This article reviews the critical role of the gut microbiome in immune system development, barrier integrity, and regulation of inflammatory and autoimmune responses. It highlights mechanisms such as short-chain fatty acid...
Tick Tubes: Stopping Lyme in Its Tracks
JACOB SCHOR, ND, FABNO This past winter, my wife and I saved all the cardboard tubes at the core of toilet paper and paper towel rolls. Today (early March), I will use them to make “tick tubes.” Our nearest neighbor, a...
Wired for Self-Healing- Part 2
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Notes from the Field: March, 2021
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Urinary Incontinence: A Common Problem for Elderly Women
THOMAS A. KRUZEL, ND Urinary incontinence affects 23-31% of the female elderly population1 and is estimated to affect 50-65% of both sexes in hospitals and nursing homes.2 Generally, older women experience more...
Nutraceuticals for Knee OA: Naturopathic Evidence-Based Strategies
DYLAN W. KRUEGER, NMD Americans work tremendously hard for the vast majority of their lives, often with the idyllic dream of an active and exciting retirement. Unfortunately, many folks reach retirement battered, beaten, and struggling with chronic diseases and...
Dementia: Depression as a Risk Factor
ROMI FUNG, ND, MSC The “Baby Boomer” generation, defined as people born between 1946 and 1964, is a demographic cohort consisting of 76 million people around the globe born during post-World War II (WWII).1 A baby boom...
Breastfeeding & Climate Change: Can Better Policies Reduce the Crisis?
KRYSTAL PLONSKI, ND, LAC, FABNP Could better policy support of breast/chest-feeding help reduce risks of climate change? Quick answer: It could, but only when it is applied on a population-based scale. From a medical...
Pediatric ADHD: Harnessing the Superpower
TERESA NEFF, ND, CLE You may have heard people speak of attention-deficit/hyperactivity disorder (ADHD) as a superpower. Its many positive aspects, such as creativity, curiosity, hyper-focus, perseverance, and energy, can and should outweigh the...
A Toxic Start to Life: Counteracting Children’s Unique Vulnerabilities
MITCH KENNEDY, ND, LEED-AP When does the onslaught of chemicals and pollutants start for each of us? Does it start in puberty as hormones possibly upregulate receptors that could inadvertently bind toxicants rather than assist the growth and...
Epigenetics: Growing Up in a Toxic World – Part I
CHRIS D. MELETIS, ND Abstract This article explores how epigenetic influences begin shaping a child’s health long before birth—and even before conception. Dr. Chris Meletis outlines how environmental toxins, nutritional deficiencies, and lifestyle factors can...
The Cast of Characters: Combating Childhood Anxiety From a Biopsychosocial Perspective
NICOLE CAIN, ND, MA Esme is a good case example of an anxious child. Her first panic attack resulted in her losing consciousness during music class. During the second attack, she felt dizzy and nauseated, and then she missed the rest of the school...
Homeopathy in Pediatrics: A Case of Chronic Digestive Disorder
SHAHRAM AYOUBZADEH ND, MD, HOM Abstract An 11-year-old female presented with a 5-year history of chronic abdominal pain, intermittent diarrhea, nausea, and marked symptom exacerbations linked to emotional stress, particularly longstanding jealousy and resentment...
Wired for Self-Healing- Part 1
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through clinical...
Promoting Planetary Health: A Necessary Part of Caring for Children
LESLIE SOLOMONIAN, BSC, ND, MPH The health of individuals is tremendously influenced by the health of their environment. This is especially true in childhood, and the effects last a lifetime. If we aim to fulfill the principles of naturopathic medicine (bolded...
Archived Case Studies and Featured Content
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Why Naturopathic Doctors Recommend Different Treatments: Understanding Individualized Care in Naturopathic Medicine
Dr. Eli Camp, ND How vitalist principles, clinical judgment, and therapeutic order shape personalized treatment strategies for the same diagnosis. Abstract This article explains why two naturopathic doctors may recommend different treatments for the same...
Curcumin Benefits and Bioavailability: Separating Mechanism from Marketing
Devin Miles, ND Abstract This article reviews the clinical evidence supporting curcumin’s role in inflammation, joint health, and oxidative stress, including comparisons with conventional therapies such as NSAIDs. It also examines the challenges of curcumin...
GLP-1 Agonists and Persistent Organic Pollutants (POPs): Lipophilic Toxin Mobilization During Rapid Fat Loss
Michael E. McEvoy, Kareem Kandil, ND This article examines the potential for rapid fat loss induced by GLP-1 agonist therapies to mobilize stored lipophilic persistent organic pollutants (POPs) from adipose tissue into circulation. It reviews evidence from weight loss...
Paris to Host Landmark Global Gathering for Naturopathic Medicine in 2026
10th Integrative & Naturopathic Medicine World Congress & Expo Returns for Its Milestone 10th Edition Paris — July 10–11, 2026 — The global stage is set for one of the most influential events in integrative healthcare as the 10th Integrative &...
Restorative Formulations Launches the NeuroSynergy Clinical Series
Four professional-grade formulas targeting distinct neurochemical pathways to support mood, stress resilience, and cognitive function are now available exclusively to licensed practitioners. Montpelier, VT, March 27, 2026 — Restorative Formulations has released the...
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Featured News
Three Endocrine Axes Share One Energy Budget for Stress Resilience
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AANP and AANMC Urge Naturopathic Community to Act: Proposed Federal Rule Threatens ND Student Loan Access and Future Workforce
Washington, DC — The American Association of Naturopathic Physicians (AANP) and the Association of Accredited Naturopathic Medical Colleges (AANMC) are calling on naturopathic physicians, students, patients, and all allies to urgently submit public comments opposing a...
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