JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
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Table of Contents | 2021
Childhood Kidney Disease: A Comprehensive Approach Holds Promise
JENNA HENDERSON, ND Abstract Nephrotic syndrome is a challenging and often relapsing kidney condition in children, with Minimal Change Nephrotic Syndrome (MCNS) being the most common form. While conventional steroid therapy remains the standard of care, many cases...
Eating Disorders: Recognizing the Signs in Preteens & Teens
LISA GHENT, ND A lot has changed since I was a kid. The rapid development of technology has introduced smart phones, gaming systems, and tablets, all of which seem to be ubiquitous, and kids are getting hooked on electronics younger and younger. With smart...
The ECS in Childhood Diseases
JAKE F. FELICE, ND, LMP Mention of the endocannabinoid system (ECS) often brings to mind cannabis and its major constituent, tetrahydrocannabinol (THC), which binds the cannabinoid-1 (CB1) receptor. These receptors...
Neuronal Hyperexcitability in PKD: Treatment Using Parenteral Therapy
2021 Student Scholarship – Second Place Case Study MATTHEW RENSHAW RUDDELL, ND LESLIE FULLER, ND Paroxysmal kinesigenic dyskinesia (PKD) is the most common paroxysmal movement disorder and is characterized by episodes of involuntary movements that are...
Amyotrophic Lateral Sclerosis: Microbiome Alterations
SAMANTHA PRYOR, ND Since this is my first article submission to NDNR, I would like to take a moment to tell you a little about myself. As I write this, I am currently employed as the last resident of the University of Bridgeport School...
Roberts’ Formula: A Natural Remedy for IBD & Gastric Ulcers
COLEEN MURPHY, ND, LAC Roberts’ Formula is a traditional naturopathic remedy with a long history of use for common digestive disorders. This abstract examines the origins of Roberts’ Formula, and how naturopathic luminaries like Dr Bastyr used and adapted...
Peripheral Neuropathy: Taking the Edge Off
CHRIS D. MELETIS, ND Neuropathy is a painful condition characterized by numbness, prickling, burning, or other pain sensations, usually in the legs, feet, and hands. Two of the most common forms of neuropathy are diabetic peripheral neuropathy and...
Rotator Cuff Calcific Tendinitis: A Case of US-Guided Single Needle Aspiration & Lavage
SERENA RUSSUM TERRANCE MANNING II, ND, RMSK A 44-year-old female presented via telemedicine with new-onset right shoulder pain. Her pain followed no obvious inciting event, and it had progressively worsened over...
The Importance of Gut Health- Part 4
JAMES SENSENIG, ND Treatments for GI Imbalances Reduce Stress, Improve Lifestyle The most obvious ways to correct gut problems are looking at how and when we eat, reducing stress, changing our lifestyle by slowing...
A Case of MS & Chronic Migraines: Treatment Using LDN & the Wahls Protocol
2021 Student Scholarship – First Place Case Study HEIDI CODINO ANGELA HARDIN, ND Multiple sclerosis (MS) is the most common demyelinating, chronic, inflammatory disease of the central nervous system (CNS).1 MS courses of disease are either...
Hashimoto’s Thyroiditis: The Impact of Nutrition
2021 Student Scholarship – Third Place Case Study PRINCESS BURNETT JENNIFER GREEN, ND Hashimoto’s thyroiditis is an inflammatory autoimmune disease in which the immune system forms antibodies to thyroid peroxidase and...
Stop and Smell the Rosemary: You Might Remember More
LILLEA HARTWELL, ND, RH (AHG) The following article is a monograph outlining the basics of Rosmarini aetheroleum essential oil (EO). The definition, synonyms, selected vernacular names, and geographical distribution of Rosmarinus...
The ECS at the Synapse
JAKE F. FELICE, ND, LMP This article discusses a newly discovered apoptogenic feature of the endocannabinoid system (ECS), known as retrograde transmission. It also discusses important influences of the ECS on neural plasticity, as well...
Migraine & the Microbiome
JESSICA BRANDES, ND According to the Migraine Research Foundation, 18% of women, 6% of men, and 10% of children in the United States experience migraines, resulting in 70% higher healthcare costs for families with a migraine sufferer than for non-migraine-affected...
Archived Case Studies and Featured Content
Quantum Fields and Frequency Medicine
RAZI BERRY Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
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Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
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