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Table of Contents | 2022
Could Poor Eyesight be Masquerading as Cognitive Decline?
From University of South Australia Millions of older people with poor vision are at risk of being misdiagnosed with mild cognitive impairments, according to a new study by the University of South Australia. Cognitive tests that rely on vision-dependent tasks could be...
Addressing Lung Failure Earlier to Prevent COPD
From La Jolla Institute for Immunology If you've ever struggled to breathe, you've had a moment of hypoxia -- a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult." Experiencing hypoxia is a known trigger for...
Processing Emotions Requires Good Sleep
From University of Bern Researchers at the Department of Neurology of the University of Bern and University Hospital Bern identified how the brain triages emotions during dream sleep to consolidate the storage of positive emotions while dampening the consolidation of...
Studying in a Variety of Conditions Improves Learning
Variability is crucially important for learning new skills. Consider learning how to serve in tennis. Should you always practice serving from the exact same location on the court, aiming at exactly the same spot? Although practising in more variable conditions will be...
Why I became a Naturopathic Doctor
Holly Lucille, ND, RN I grew up in the Midwest, the daughter of two pharmacists, and was very well versed in the Western medical approach: “You don’t feel well? Here, take this pill.” Even at a very young age I was troubled by this approach to health and always...
Notes from the Field- March 2022
JARED L. ZEFF, ND, VNMI, LAC The following is not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be...
Take a Break from Social Media to Improve Mental Health
From University of Bath Asking people to stop using social media for just one week could lead to significant improvements in their wellbeing, depression and anxiety and could, in the future, be recommended as a way to help people manage their mental health say the...
A Mechanism for Preventing Build up of Toxic Proteins Leading to Dementia 
From University of Cambridge It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in...
Hormone Regulator of Low-Protein Diet Benefits
From Pennington Biomedical Research Center A single hormone appears to coordinate the lifespan extension produced by a low-protein diet. A new study from Pennington Biomedical Research Center, published in the journal Nature Communications, found that reducing the...
Gut Microbiome Can Tell Us About Concussion Status
From Houston Methodist A recently published study by Houston Methodist scientists suggests telltale signs of concussions might be found in the gut. By taking blood, stool and saliva samples from 33 Rice University football players, the researchers were able to examine...
Increased Chemical Exposure in Pregnant Women
From University of California - San Francisco A national study that enrolled a highly diverse group of pregnant women over 12 years found rising exposure to chemicals from plastics and pesticides that may be harmful to development. Many of the chemicals that the women...
Botanicals for Graves’ Disease
Botanicals for Graves’ Disease An Herbal Case Study BRIAN KEENAN, ND, LAC During my early years as a clinical intern I was tasked with seeing a new patient who was considered difficult. She was irritable, untrusting, and many in the clinic had...
Melatonin & Glucose Homeostasis
A Complex Relationship GINA BROWN RICK BHIM, ND, CCNM Type 2 diabetes (T2DM) is a global health concern, affecting over 462 million individuals worldwide.1 It is a widely common condition in clinical practice and is a significant burden on the healthcare...
Linking Heart Disease in People with Diabetes Using Gene Mapping
From American Heart Association A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed...
Exploring Electrical Synapses in the Brain
From Max-Planck-Gesellschaft They are part of the brain of almost every animal species, yet they remain usually invisible even under the electron microscope. "Electrical synapses are like the dark matter of the brain," says Alexander Borst, director at the MPI for...
Archived Case Studies and Featured Content
Male Infertility and Pain Medication: When Analgesic Exposure Becomes a Fertility Clue
Could overlooked pain-medication use provide an important clue in male infertility? This case follows a 40-year-old man with oligoasthenoteratozoospermia whose total motile sperm count increased from 2.72 million to 26.5 million over 111 days following analgesic discontinuation and a multicomponent integrative fertility plan.
Cardiovascular Risk Assessment in Men: A Naturopathic Cardiology Perspective
Cardiovascular risk extends beyond LDL cholesterol and the standard lipid panel. This review explores how plaque biology, inflammation, oxidation, metabolic and hormonal health, advanced biomarkers, CGM, and cardiovascular imaging can complement established therapies to create a more individualized approach to cardiovascular risk assessment in men.
The Role of Hormonal Changes in the Etiology and Treatment of Paternal Perinatal Mood and Anxiety Disorders
Approximately 1 in 10 fathers experience a perinatal mood or anxiety disorder, yet paternal PMADs remain frequently overlooked. This review explores the hormonal and psychosocial changes accompanying fatherhood and their implications for recognizing, screening, and supporting paternal mental health.
Oral Curcumin and Artesunate Protocol in Prostatic Carcinoma: Case Study Series in PSA and Pathology Outcomes
Can curcumin and artesunate play a role in integrative prostate cancer care? This two-patient case series examines PSA trajectories and pathology during an oral botanical protocol incorporating curcumin and artesunate, while highlighting potential mechanisms, iron-related adverse effects, and the need for further clinical investigation.
From PCOS to PMOS: What the Name Change Means for Your Practice
Dr. Jaclyn Smeaton, ND A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...
Collaborative Fertility Care: How Naturopathic Doctors and Nurse Practitioners Can Expand Integrative Treatment Options
Dr. Nora Pope ND, FCP A clinical exploration of how collaborative ND–NP care can bridge prescribing limitations, integrate restorative fertility strategies, and expand access to individualized reproductive treatment. This article examines the clinical value of...
Resolving Fatigue, Food Sensitivities, and PMS in a 38-Year-Old Female: A Gut–HPA Axis Case Report
Dr. Brian Lamoreux, ND, MA, LPCC A clinical case exploring the interconnected roles of HPA axis dysfunction, gut dysbiosis, food reactivity, and stress physiology in new-onset fatigue and premenstrual symptoms. This case report follows a 38-year-old woman with...
Progesterone Resistance and Implantation Failure: An Integrative Approach to Endometrial Receptivity
Dr. BreAnna Guan, ND A whole-person exploration of how inflammation, endocrine disruptors, metabolic dysfunction, gut dysbiosis, and stress may impair progesterone signaling and compromise fertility. This article examines progesterone resistance as an...
Age-Related Fertility Decline: Improving Oocyte Quality Through Integrative Naturopathic Care
Dr. Shannon Sinsheimer, ND A clinical review of mitochondrial dysfunction, oxidative stress, and evidence-informed nutritional strategies to support oocyte maturation, embryo quality, and successful conception in advanced reproductive age. This article explores...
Restoration of Cycle Regularity and Healthy Pregnancy in a 41-Year-Old Woman with Diminished Ovarian Reserve: A Naturopathic Case Report
Dr. Aumatma Simmons, ND A root-cause fertility case exploring hormonal optimization, vaginal microbiome restoration, luteal phase support, and individualized naturopathic care in advanced reproductive age. This case report details the successful restoration of...
Natural Conception Following Ovarian PRP and Integrative Naturopathic Fertility Care: Two Case Reports
Dr. Emmalyn Pratt, ND Two fertility case reports exploring the potential role of ovarian platelet-rich plasma (PRP) alongside naturopathic interventions in women with diminished ovarian reserve, recurrent pregnancy loss, and failed assisted reproductive...
From Protocols to Precision: Using Organic Acid Testing to Personalize IVF Preparation
Dr. Shannon Iselin, ND How metabolomic assessment of oxidative stress, mitochondrial function, and nutrient sufficiency may help optimize reproductive outcomes beyond conventional fertility markers. This article explores the potential role of organic acid...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...
Rethinking Mental Health Treatment: The Clinical Case for Natural Neurotransmitter Support
Dr. Jaquel Patterson, ND, Dr. Elizabeth Sutherland, ND, and Dr. Devin Miles, ND A clinical review of evidence-based botanical and nutritional compounds that support serotonergic, dopaminergic, GABAergic, and stress-response pathways in...
Restoration of Cycle Regularity and Healthy Pregnancy in a 41-Year-Old Woman with Diminished Ovarian Reserve: A Naturopathic Case Report
Dr. Aumatma Simmons, ND A root-cause fertility case exploring hormonal optimization, vaginal microbiome restoration, luteal phase support, and individualized naturopathic care in advanced reproductive age. This case report details the successful restoration of...
Natural Conception Following Ovarian PRP and Integrative Naturopathic Fertility Care: Two Case Reports
Dr. Emmalyn Pratt, ND Two fertility case reports exploring the potential role of ovarian platelet-rich plasma (PRP) alongside naturopathic interventions in women with diminished ovarian reserve, recurrent pregnancy loss, and failed assisted reproductive...
From Protocols to Precision: Using Organic Acid Testing to Personalize IVF Preparation
Dr. Shannon Iselin, ND How metabolomic assessment of oxidative stress, mitochondrial function, and nutrient sufficiency may help optimize reproductive outcomes beyond conventional fertility markers. This article explores the potential role of organic acid...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...
Rethinking Mental Health Treatment: The Clinical Case for Natural Neurotransmitter Support
Dr. Jaquel Patterson, ND, Dr. Elizabeth Sutherland, ND, and Dr. Devin Miles, ND A clinical review of evidence-based botanical and nutritional compounds that support serotonergic, dopaminergic, GABAergic, and stress-response pathways in...
Ovulation-Triggered Migraine: A Naturopathic Clinical Case Study
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
Mediterranean Diet and Olive Oil in Women’s Health: Clinical Evidence and Applications
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Naturopathic Dementia Prevention: Clinical Strategies for Neurodegeneration
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
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Featured News
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...
AANP and AANMC Urge Naturopathic Community to Act: Proposed Federal Rule Threatens ND Student Loan Access and Future Workforce
Washington, DC — The American Association of Naturopathic Physicians (AANP) and the Association of Accredited Naturopathic Medical Colleges (AANMC) are calling on naturopathic physicians, students, patients, and all allies to urgently submit public comments opposing a...












