Melissa Sophia Joy, ND Vitalism is a cornerstone of the naturopathic worldview, underpinning many of its core tenets and healing modalities. Vitalism has been described as “the doctrine that life originates in a vital principle, distinct from chemical and other...
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Table of Contents | 2025
Hormonal, Neurological & Gut-Brain Restoration in Chronic Migraine: A Case Study
Anna Kolomitseva, ND A 46-year-old woman achieved complete and sustained migraine remission using a personalized, systems-based naturopathic protocol that addressed hormonal imbalance, gut dysbiosis, and neurological dysregulation. Abstract Migraines are a prevalent...
Reams’ Analysis in Practice: A Bio-Electric Framework for Naturopathic Assessment
Darrell Misak, ND Every practitioner navigates through a range of plausible explanations of disease presentations to develop a rational assessment and supportive protocol aimed at achieving positive clinical outcomes. What if a basic analytical assessment could...
Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration
By Devin Miles, ND and Elizabeth Sutherland, ND Emerging research highlights TUDCA’s potential to reduce neuroinflammation, prevent cell death, and mitigate the effects of metabolic dysfunction in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and...
The Breath of Life: Mastering the Art of Conscious Breathing
Jennifer Ruthensteiner, ND Breath sustains life, yet in today’s fast-paced world, it often becomes a neglected tool. Ancient traditions revered breath as the essence of life, linking body, mind, and spirit. Modern life, however, fosters shallow breathing patterns that...
Healing the Gut to Calm the Mind: A Case Study in Pediatric Anxiety and OCD-Like Behavior
Alexander Arrington, ND A 7-year-old male experienced complete remission of severe anxiety and obsessive-compulsive behaviors following targeted microbiome and nutritional therapy. Abstract A 7-year-old male presented with sudden-onset severe anxiety and...
The Mind-Body Bridge: Naturopathic Philosophy Meets Psychotherapy & Neuroscience
Alina Soto, ND, LMHCA “The mind as an emergent property of the body and relationships is created within internal neurophysiological processes and relational experiences. In other words, the mind is a process that emerges from the distributed nervous system extending...
The Link Between Leaky Gut, Food Sensitivities, and Anxiety
Discover how leaky gut and common food sensitivities like gluten and dairy contribute to anxiety by triggering inflammation and disrupting the gut-brain axis. Tiffany Jackson, ND Abstract Leaky gut—characterized by increased intestinal permeability—emerges as a key...
Mental Health’s Flat Earth: Why It’s Time to Abandon the DSM and Face the Illusion of Diagnosis
Steven Rondeau BCN (EEG), qEEG-DL The DSM offers outdated labels based on symptoms, not biology. qEEG and brain mapping provide objective insights that empower more accurate, personalized mental health care. Diagnosing in the Dark: The Problem Psychiatry Refuses...
Ketamine-Assisted Psychotherapy: History, Clinical Uses, and Case Example
Conor Watters, ND, MSAS, PATP From battlefield anesthesia to mental health treatment, ketamine has evolved into a powerful therapeutic tool. Explore its origins, modern psychiatric applications, and a detailed case study demonstrating its potential in...
Sleeping Well During Dynamic Societal Change
How to Protect Sleep Health Amid Political, Economic, and Social Upheaval Catherine Darley, ND Periods of major government and societal change often trigger widespread uncertainty, leading to a rise in sleep complaints. Many clinicians are seeing this firsthand among...
Anticipatory Anxiety: A Case Study in Individualized Homeopathic Care
Michael Knapp, ND, DHANP A compelling case of chronic anxiety, compulsive behavior, and digestive distress resolved through precise homeopathic prescribing guided by pattern recognition and physical symptom correlation. Abstract A 25-year-old male with lifelong...
June 2025 Cont. References
Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...
A Root-Cause Approach to Menopausal Insomnia and Brain Dysfunction: A Case Study
Discover how a 48-year-old woman overcame chronic insomnia, fatigue, and cognitive decline during menopause through a personalized, brain-first, hormone-balancing approach. Stephanie Yang, ND Abstract Menopause is not only a hormonal milestone but also a neurological...
Seeing Beyond the Mirror: How Psilocybin Could Transform Body Dysmorphic Disorder Treatment
Georgiana Cullen-Kerney, ND, LAc Emerging research reveals that psilocybin, the active compound in magic mushrooms, may offer a groundbreaking approach to treating Body Dysmorphic Disorder (BDD) by enhancing cognitive flexibility and reducing obsessive thought...
Archived Case Studies and Featured Content
Nigella sativa: The Ancient Herbal Remedy Supporting Thyroid Resilience in Hashimoto’s Thyroiditis
Lillea Hartwell, ND A comprehensive review of Nigella sativa seed oil, its active constituents, safety profile, pharmacology, and emerging clinical evidence for supporting immune regulation and thyroid function in Hashimoto’s thyroiditis. This monograph reviews...
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow within integrative and naturopathic...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
Dr. Vy Simeles, ND, Restorative Health Clinic A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Abstract This case report details the recovery of a...
Infection, Neuroinflammation, and Immune Dysregulation: The Clinical Overlap of Lyme Disease and PANS/PANDAS and a Path to Healing
Understanding the clinical overlap between vector-borne infections and pediatric acute-onset neuropsychiatric syndromes—and a systems-based integrative path to healing. Dr. Myriah Hinchey, ND, FMAPS Abstract This article examines the biological overlap between Lyme...
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Dr. Chris D Meletis Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
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Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Featured News
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Strive Compounding Pharmacy Files Federal Antitrust Lawsuit Against Eli Lilly and Novo Nordisk
ARCADIA TALLMAN Strive Compounding Pharmacy has filed a federal antitrust lawsuit against Eli Lilly and Novo Nordisk, alleging a coordinated effort to suppress competition and restrict patient access to lawful compounded GLP-1 medications. The complaint, filed on...
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