Mechanisms of Aging and Neurodegeneration
Dr. Jaquel Patterson

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Featured Article | Anti-Aging

The Brave New World of eLearning: Let’s Not Strap on Feathered Wings

The Brave New World of eLearning: Let’s Not Strap on Feathered Wings

Education  David J. Schleich, PhD Dickens nailed it when he wrote in 1859, “It was the best of times; it was the worst of times.” [A Tale of Two Cities] Two centuries later, the best and the worst are before us in the higher education and healthcare terrains. There is...

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Mechanisms of Nutrient Action in Bone Tissue

Rebecka Hoppins Campbell, ND Osteoporosis is defined as a “systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture” (Consensus Development...

Age-Related Macular Degeneration

Paul S. Anderson, ND Age-related macular degeneration (AMD) is the leading cause of functional blindness in humans older than age 65 in developed countries around the world (American Academy of Ophthalmology, 2001). It is estimated that currently, 1.75 million people...

Anti-Aging Nutrition and Phytotherapy

“Old age itself is not a disease, but a condition which may lead to illness on various levels due to the hyporeactivity characteristic of this state … Aging constitutes an inability to correctly respond to various rivaling stimuli.” – Bianchi, 1994 Treating patients...

Oxytocin: The Big “O” in Women’s Well-Being

Trina Doerfler, ND, DC Oxytocin is a hormone that has been given too little attention outside the well-known arenas of parturition and lactation, and much too little respect in its power to restore health and well-being in today’s modern women. Far more than an agent...

Reclaiming the Power of Blood

Kristina Conner, ND We’ve come a long way in attitudes about menstruation. In many native cultures, women were often separated during menstruation, forbidden to perform household tasks or communicate with other group members. It was considered natural, but also...

Menopause and Retaining the Female Libido

Emily A. Kane, ND, LAc A sexy woman is, by and large, a young and healthy woman. Typically a young, healthy, reasonably happy and sexy woman has a “normal” libido. A woman who has matured beyond her reproductive years may “suffer” from reduced libido, as all purveyors...

The Relationship Between Adrenal Function and Menopausal Symptoms

Kathryn Retzler, ND Many clinicians have observed the increased severity of menopause-related symptoms in patients who have experienced chronic stress. Since the adrenal glands “take over” sex hormone production postmenopausally, holistic treatment for menopausal...

Hypochlorhydria and Homocysteine in Mild Cognitive Impairment

Gene Bowman, ND In the October issue of NDNR, we reviewed relationships between hypochlorhydria, micronutrients and gut flora pertinent to dementia. This article will extend these ideas to Alzheimer’s disease, neurocognitive testing and rationale for clinical...

Archived Case Studies and Featured Content

The Link Between Leaky Gut, Food Sensitivities, and Anxiety

Discover how leaky gut and common food sensitivities like gluten and dairy contribute to anxiety by triggering inflammation and disrupting the gut-brain axis. Tiffany Jackson, ND Abstract Leaky gut—characterized by increased intestinal permeability—emerges as a key...

Sleeping Well During Dynamic Societal Change

How to Protect Sleep Health Amid Political, Economic, and Social Upheaval Catherine Darley, ND Periods of major government and societal change often trigger widespread uncertainty, leading to a rise in sleep complaints. Many clinicians are seeing this firsthand among...

June 2025 Cont. References

Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...

Nighttime Urination and Sleep Apnea: The Overlooked Connection

Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...

June 2025 Cont. References

Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...

Nighttime Urination and Sleep Apnea: The Overlooked Connection

Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...

Flavor as Medicine: The Science of Taste is Key to Better Health

Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...

Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle

Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...

Depression Appears 8 Years Before Pain Begins

Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...

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