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Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
Featured Article | Autoimmune/Allergy Medicine
Using Far-UVC Light to Sanitize Indoor Air
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER A new type of ultraviolet light that is safe for people took less than five minutes to reduce the level of indoor airborne microbes by more than 98%, a joint study by scientists at Columbia University Vagelos College of...
Exclusive Content | Autoimmune/Allergy Medicine
Histamine Intolerance: A Common Cause of Chronic Complaints
Krista Moyer, ND Abstract Histamine intolerance is an underrecognized contributor to a wide range of chronic, multisystem symptoms often misattributed to other conditions. Impaired activity of the diamine oxidase (DAO) enzyme in the gastrointestinal tract can lead to...
Autoimmune Disease: The Importance of Family History
Chad Larson, NMD, DC, CCN, CSCS In the past 2 weeks, I diagnosed a middle-aged male with celiac disease, and a teenage female with Hashimoto’s thyroiditis. Since their symptoms weren’t really textbook for those conditions, it was their positive family history for...
Microbial Origins of Fibromyalgia
Alex Vasquez, DC, ND, DO, FACN For the accurate understanding and effective treatment of any disease, all components of the disease should first be integrated into a cohesive and consistent model that explains all aspects of the disease, including risk factors,...
Astragalus: Use of the Herb in the Treatment of Allergy & Autoimmunity
Jillian Stansbury, ND Astragalus membranaceus, going by the common names Huangqui in China, and milk vetch in the United States, is one of the most fundamental herbs used in Traditional Chinese Medicine. Astragalus roots have also been used as a medicinal food by...
Mast Cell Activation Syndrome
Katherine Hampilos Wendy Hodsdon, ND Mast Cell Activation Syndrome (MCAS) is an idiopathic disorder of inappropriate mast cell activation and increased mediator release, despite a normal total number of mast cells.2 Patients with MCAS present with chronic multi-system...
Triggers of Autoimmune Disease
Amanda Hegnauer, ND Around 80 to 100 different autoimmune diseases have been identified, and at least 40 more diseases may have an autoimmune basis.1 The National Institutes of Health (NIH) estimates that roughly 23.5 million Americans suffer from autoimmunity,...
Salicylate Sensitivity: The Other Food Intolerance
Donna Beck, ND “I just don’t understand it, Doctor. I’m not like my other friends. They all seem to be thriving on gluten-free diets or the Mediterranean diet or the Paleo diet – not me! Wheat and gluten products don’t bother me at all. In fact, it seems to be one of...
Anti-inflammatory Probiotics: Immunomodulation in the Gut and Beyond
Fiona McCulloch, BSc, RAc ND The immune system is divided into 2 segments – the innate and the adaptive immune system. These 2 arms work together synergistically to protect the host from infectious disease. In mammals, the adaptive immune system includes both the...
Archived Case Studies and Featured Content
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
Dr. Vy Simeles, ND, Restorative Health Clinic A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Abstract This case report details the recovery of a...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
Dr. Vy Simeles, ND, Restorative Health Clinic A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Abstract This case report details the recovery of a...
Infection, Neuroinflammation, and Immune Dysregulation: The Clinical Overlap of Lyme Disease and PANS/PANDAS and a Path to Healing
Understanding the clinical overlap between vector-borne infections and pediatric acute-onset neuropsychiatric syndromes—and a systems-based integrative path to healing. Dr. Myriah Hinchey, ND, FMAPS Abstract This article examines the biological overlap between Lyme...
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Dr. Chris D Meletis Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Adam Livingston: The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
https://youtube.com/shorts/KiCTEZDh3mc
Dr. Bush Bradley And The Role of Histamine and Serotonin in Upper GI Motility
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Featured News
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...



















