Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
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Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
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Featured Article | Endocrinology
Infertility Case Study: It’s Usually Never Just 1 Thing
Tolle Totum Reena Singh, ND Infertility affects 1 out of 8 couples1 and can be a sign of other imbalances and deficiencies in the body. When HG presented to my office, she was a 38-year-old woman who had been trying to get pregnant for 12 years. She had already...
Exclusive Content | Endocrinology
The Age of Menarche: The Effect of Endocrine-Disrupting Compounds and other Environmental Factors
Kristina Conner, ND The rise of endocrine disorders is particularly significant to naturopathic practice, given the strong correlation of endocrine function to the determinants of health. We expect that due to lifestyle in contemporary Western lifestyle, normal...
Treatment of Lymphoma with Helixor: A Case Study
Beverly Huang, ND JW, 78 years old, first presented to me in July 2008, after months of feeling unwell and having been diagnosed with Stage 3B diffuse large B-cell lymphoma a month earlier. Diffuse large B-cell lymphoma is a non-Hodgkin lymphoma; it is a high-grade...
Anti Aging: Wrinkle and Skin Slack Treatment
Michael Rahman, BSc, ND My belief is that health is beauty and beauty is health. As an ND, I strive to marry natural medicine with cosmetic and anti-aging medicine. A comprehensive approach to anti-aging means not only assessing possible endocrine, metabolic or...
Kfar Saba Syndrome
Jacob Schor, ND, FABNO I’ve seen three cases of ”Kfar Saba Syndrome” in as many weeks. Don’t go rushing off to look up this condition in your Merck Manual; it’s not listed. It’s my own name for the triad hypothyroidism, iron deficiency and B12 deficiency in the same...
Autoimmunity and the Role of Women’s Hormones
Mary Shackelton, MPH, ND The topic of autoimmunity is vast and complicated. Clinicians working with a female demographic have undoubtedly encountered many conditions related to autoimmunity and have perhaps questioned female-specific variables that affect the...
Carcinoid: The Zebra Diagnosis
Gurdev Parmar, ND, FABNO and Jacob Schor, ND, FABNO I found great consolation in reading a case that co-author Gurdev Parmar sent me recently. Discovering that an astute practitioner like Dr. Parmar made the same mistake I once did brings me solace. Here’s a brief of...
Improving Estrogen Dominance With Food and Herbal Medicine
Jillian Stansbury, ND Estrogen dominance is extremely common in the general U.S. population and is associated with the discomforts of PMS, the pathologies of breast cysts, ovarian cysts and uterine fibroids, as well as contributory to the emergence of hormone-related...
Irregular Menstruation: Overview and Case Studies
Marie Rodriguez, ND Many women report getting periods early, late or even skipping a period altogether during times of greater stress – a move, travel, new job, etc. Irregular periods can affect up to 20% of women, and are often harmless. It is when a woman reports...
Archived Case Studies and Featured Content
Approaching Idiopathic Neuropathy: A Naturopathic Strategy Beyond Diabetes
A clinical overview of diagnosing and treating non-diabetic neuropathy through root-cause evaluation, including autoimmunity, infections, biotoxin exposure, and small fiber nerve pathology. Dr. Jason Porter, NMD Abstract This article explores a naturopathic framework...
Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body
An in-depth exploration of how somatic awareness, interoception, and relational neuroscience can support nervous system regulation, authenticity, and healing in clinical practice. Allison Creech, M.Ed., ND Abstract This article examines mind-body medicine as a...
Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Dr. Nicole Roberts, ND Abstract In this case report, we see a 48-year-old female, over...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Dr. Leslie Solomonian, ND Abstract This article examines rising...
Anticipatory Anxiety: A Case Study in Individualized Homeopathic Care
Michael Knapp, ND, DHANP A compelling case of chronic anxiety, compulsive behavior, and digestive distress resolved through precise homeopathic prescribing guided by pattern recognition and physical symptom correlation. Abstract A 25-year-old male with lifelong...
June 2025 Cont. References
Tauroursodeoxycholic Acid (TUDCA) And Protective Role Against Neurodegeneration Authors: Devin Miles, ND and Elizabeth Sutherland, ND Zangerolamo L, Vettorazzi JF, Rosa LRO, et al. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May...
A Root-Cause Approach to Menopausal Insomnia and Brain Dysfunction: A Case Study
Discover how a 48-year-old woman overcame chronic insomnia, fatigue, and cognitive decline during menopause through a personalized, brain-first, hormone-balancing approach. Stephanie Yang, ND Abstract Menopause is not only a hormonal milestone but also a neurological...
Seeing Beyond the Mirror: How Psilocybin Could Transform Body Dysmorphic Disorder Treatment
Georgiana Cullen-Kerney, ND, LAc Emerging research reveals that psilocybin, the active compound in magic mushrooms, may offer a groundbreaking approach to treating Body Dysmorphic Disorder (BDD) by enhancing cognitive flexibility and reducing obsessive thought...
Nighttime Urination and Sleep Apnea: The Overlooked Connection
Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...
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Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Flavor as Medicine: The Science of Taste is Key to Better Health
Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...
Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle
Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Depression Appears 8 Years Before Pain Begins
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...
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Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Flavor as Medicine: The Science of Taste is Key to Better Health
Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...
Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle
Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Depression Appears 8 Years Before Pain Begins
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...
Resolving Acne Vulgaris Through Gut and Hormone Support: A Case Study
By Chelsea Smithback, ND Introduction Acne vulgaris is a very common skin condition, with a prevalence rate ranging from 25% to 95% among adolescents. It is more common in males than females. Acne can persist into adulthood or have a delayed onset during this stage of...
Targeting Menopausal Acne: Hormone Balancing and Skin Barrier Support in Practice
Aarti Patel, ND ABSTRACT This case study explores menopausal acne in a 55-year-old female with severe skin barrier damage from a history of using medical-grade prescription, as well as over-the-counter acne topicals, along with a more recent history of supplementing...
Mechanisms of Aging and Neurodegeneration
Exploring Thiamine Deficiency, Catecholamine Toxicity, and Angiotensin II Quinn Rivet, ND Exploring how thiamine deficiency, catecholamine-induced neurotoxicity, and Angiotensin II contribute to neurodegeneration and aging in the brain. Introduction This paper aims to...
Breaking the Cycle: Understanding PCOS-Related Skin Manifestations
Pathophysiology, Clinical Implications, and Evidence-Based Naturopathic Interventions Galina Mironova, ND Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder with systemic effects, including significant dermatologic manifestations. Acne, hirsutism,...
New Research Validates Naturopathic View of Neurological Disease
Golf course herbicides cause dopaminergic neuron death and initiate Parkinson's disease Decades of naturopathic medicine casework on pesticide-linked neurological decline are now confirmed by population-based data showing increased Parkinson's risk near golf courses....
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Featured News
Resveratrol–Copper Combination Suppresses Glioblastoma Growth and Restores Immune Function
Tumor proliferation suppressed, immune function restored, and harmful DNA cleared with no adverse reactions reported Glioblastoma multiforme (GBM) remains among the deadliest primary brain cancers, notoriously resistant to current treatments. A 2025 pilot clinical...
Pharmacists Continue to Dispense Antidepressants Despite Hesitation, Study Finds
Pharmacists Fear Discussing Antidepressant Risks, Leaving Patients Uninformed and Overmedicated The Serotonin Theory Has Been Debunked For decades, depression treatments rested on a simple theory: low serotonin caused depression. An expansive, rigorous analysis of...










