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Male Infertility and Pain Medication: When Analgesic Exposure Becomes a Fertility Clue
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Trending Articles
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Featured Article | Gastrointestinal
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a...
Exclusive Content | Gastrointestinal
Nature Cure Clinical Pearls: Dyspepsia
Sussanna Czeranko, ND, BBE There are probably more persons in the world today suffering from indigestion than from any other known ailment. And so long as people eat too much, too fast, and improperly, they will have stomach troubles. ~ William James Cromie, 1902,...
Psychiatric Disorders: Targeting the Microbiome
Student Scholarship Honorable Mention Alexandra Francis, ND, MS, CNSMarie Winters, ND, FABNO Abstract This article reviews evidence that dysbiosis and intestinal hyperpermeability drive neuroinflammation and neurotransmitter imbalance along the gut–brain axis,...
Prebiotics & Metabolic Regulation: Benefits Beyond the Gut
Tolle Totum Erick R. Cervantes, MPH, ND Dale Pfost, PhD Human beings are host to a diverse ecosystem known as the microbiome. Characteristic of our microbiome, among many other things, is its now well-known diversity within the individual and from person to person, as...
US Cannabis Regulation: What It Means for Naturopathic Doctors
Docere Shaon Hines, ND Much confusion exists regarding Cannabis, marijuana, and hemp. A better understanding of the terminology will help you to understand the legality. The terms “Cannabis” and “medical marijuana” are often used interchangeably. Cannabis, however, is...
Gut Dysbiosis: An Underlying Cause of Obesity
Tolle Causam Alison Chen, ND The obesity epidemic has long been recognized as a fight against excessive calorie consumption and a sedentary lifestyle. Despite these well-known contributors, obesity rates continue to rise. In the United States, obesity prevalence for...
Surfing The Microbiome: Interview with Richard Sprague
The Expert Report Mark Swanson, ND Let me introduce Richard Sprague to the readers of The Expert Report. He is an amazing citizen scientist. I'll start with one of his quotes regarding our topic, the gut microbiome. Why microbiome testing is important is that unlike...
GI Dysfunction in Parkinson’s: A Naturopathic Approach
Emma M. N. Petshow Carrie Baldwin-Sayre, ND Student Scholarship – First Place Case Study Parkinson’s disease is a neurologic disorder that affects the substantia nigra of the brain by depleting dopamine-secreting neurons.1 Gastrointestinal distress, including nausea,...
IBS with Obesity
Justin Wise, CA, BComm Peter K. Raisanen, NMD, BSc Student Scholarship – Second Place Case Study Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by chronic abdominal pain, bloating, and changes in bowel habit.1 IBS is categorized...
Archived Case Studies and Featured Content
A New Chapter in Pain Pharmacology: Suzetrigine, NaV1.8 Inhibition, and the Future of Non-Opioid Analgesia
Suzetrigine introduces a novel mechanism for treating moderate to severe acute pain by selectively inhibiting NaV1.8 channels on peripheral nociceptors. This review examines its mechanism, clinical efficacy, safety, and potential role within multimodal naturopathic and integrative pain management.
Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance
Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.
Breath of Fresh Air for the Profession: Reflections from AANP 2026 in Madison
The 2026 American Association of Naturopathic Physicians (AANP) Convention arrived in Madison, Wisconsin, under unusual skies. Wildfire smoke had drifted across the region, leaving the city enveloped in smoke and fog as naturopathic physicians, students, educators,...
Daraxonrasib and Pancreatic Cancer: A Breakthrough for Precision and Integrative and Naturopathic Oncology
Daraxonrasib is reshaping the therapeutic landscape of RAS-driven pancreatic cancer and raising new considerations for integrative clinicians. This article explores pan-RAS inhibition alongside practical strategies for nutrition, exercise, symptom management, and careful evaluation of botanical and nutrient interactions within a precision integrative oncology framework.
Ovulation-Triggered Migraine: A Naturopathic Clinical Case Study
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
Mediterranean Diet and Olive Oil in Women’s Health: Clinical Evidence and Applications
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Naturopathic Dementia Prevention: Clinical Strategies for Neurodegeneration
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Why Naturopathic Doctors Recommend Different Treatments: Understanding Individualized Care in Naturopathic Medicine
Dr. Eli Camp, ND How vitalist principles, clinical judgment, and therapeutic order shape personalized treatment strategies for the same diagnosis. Abstract This article explains why two naturopathic doctors may recommend different treatments for the same...
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ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
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