Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...

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Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
Featured Article | Nature Cure
Wired for Self-Healing- Part 3
JAMES SENSENIG, ND LOUISE EDWARDS, ND, LAC This column is transcribed from a weekly live conversation produced by the Naturopathic Medical Institute (NMI). The goal of NMI is to preserve and promote the principles of naturopathic philosophy through...
Exclusive Content | Nature Cure
Materia Medica Review for Gastrointestinal Inflammation
Clinical Pearls for Pain Jillian Stansbury, ND Abstract Gastrointestinal inflammation is a pervasive concern in clinical practice, encompassing conditions such as irritable bowel syndrome, food intolerances, ulcerative disorders, infections, and dysbiosis. Herbal...
Ayurvedic Antiaging Therapies: Reversing Diseases and Living to the Fullest
Virender Sodhi, MD (Ayurved), ND Ayurvedic medicine has delineated rejuvenation and virilification as a branch of medicine where the main objectives are to maintain health as age advances and to keep the sexual organs healthy, avoiding the transfer of diseases to our...
Unfired Food and Apyrotrophy
Nature Cure Sussanna Czeranko, ND, BBE Americans who eat meat three times a day and wash their meals down with coffee, tea, and ice water are a nation of dyspeptics, employing a vast army of physicians and dentists and spending millions of dollars for poisonous drugs...
Reduce Hot Flashes and Other Menopausal Symptoms: A Beneficial Proprietary Siberian Rhubarb Root Extract
Kristen Haabala, ND Mark Kaye, DC Menopause is the clinical term used after menstruation has ceased for 1 year, after which women are considered postmenopausal.1 In the last 1 to 2 years before the final menstrual period, estrogen loss accelerates, and menopausal...
The Current Healing Crisis—Part 2
Why Anthroposophically Enhanced Medicine? Robert B. Kellum, ND, PhD, MSOM/LAc, LMT Click to Read Part - 1 Click to Read Part - 2 Click to Read Part - 3 Click to Read Part - 4 Finding the Causative Factors of Illness In his discussion of “therapeutic order” in...
Throwing the Baby Out With the Bathtub
Infertility and Traditional Treatments Sussanna Czeranko, ND, BBE Amongst the innumerable treatments in the great domain of Natural Methods of Healing, the Thure Brandt method is the most unique. -Carola Staden, 1900, p. 23 The fact that the...
For the Love of Peat: Infertility Has a Chance
Sussanna Czeranko, ND, BBE The number of women who will be sitting in waiting rooms this year, anxious and wishing for good news, will number more than 7 million. If more than 7 million partners are sitting at home waiting for their wives to return with the good news,...
Bright Disease
Natures Cure Sussanna Czeranko, ND, BBE In all chronic diseases, the most important thing is not to lose patience, and not to entertain the idea that one can effect a cure in six weeks, of a disease that has taken years to develop. ...
Archived Case Studies and Featured Content
Rethinking Mental Health Treatment: The Clinical Case for Natural Neurotransmitter Support
Dr. Jaquel Patterson, ND, Dr. Elizabeth Sutherland, ND, and Dr. Devin Miles, ND A clinical review of evidence-based botanical and nutritional compounds that support serotonergic, dopaminergic, GABAergic, and stress-response pathways in...
Ovulation-Triggered Migraine: A Naturopathic Clinical Case Study
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
Mediterranean Diet and Olive Oil in Women’s Health: Clinical Evidence and Applications
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
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Flavor as Medicine: The Science of Taste is Key to Better Health
Flavors Are Neuroendocrine Signals That Direct Nutrient Intake and Body Metabolism Have you ever wondered why certain foods taste delicious during childhood or why adolescents seem drawn to bold flavors? From infancy through adolescence, our bodies are hardwired to...





