By Lina Mockus, ND How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and what integrative care can do about it. This article explores the shared metabolic, inflammatory, and microbiome-driven...
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Arterial Plaque Regression: A Case-Based, Integrative Approach to Cardiovascular Risk Reduction
Dr. Stephen Parcell, ND A preventive cardiology case demonstrates how advanced imaging, aggressive lipid optimization, and integrative therapies can reduce coronary plaque burden in a high-risk patient. This case report examines the regression of coronary...
Resolution of Exercise-Induced Asthma with Individualized Homeopathic Treatment: A Case Report
Dr. Michael Knapp, ND, DHANP A case demonstrating sustained remission of exercise-induced asthma, allergic oropharyngeal symptoms, and recurrent respiratory infections in an adolescent following constitutional homeopathic care. This case report describes the...
Managing Elevated Coronary Artery Calcium Scores: An Updated Clinical Guide
Dr. Joel Kahn, MD, FACC A step-by-step, evidence-informed framework for interpreting high coronary calcium CT results, refining cardiovascular risk, and implementing integrative prevention strategies. Abstract This article provides an updated, clinically...
Closing the Care Gap in Atrial Fibrillation: An Evidenced-Based Role for Naturopathic Doctors
Dr. Olivia Greenspan, ND RN Abstract Structured risk factor modification and longitudinal lifestyle care can improve atrial fibrillation outcomes beyond rate and rhythm control alone. This article examines atrial fibrillation as a progressive, risk...
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Featured Article | Neurology
Exploring Electrical Synapses in the Brain
From Max-Planck-Gesellschaft They are part of the brain of almost every animal species, yet they remain usually invisible even under the electron microscope. "Electrical synapses are like the dark matter of the brain," says Alexander Borst, director at the MPI for...
Exclusive Content | Neurology
MTHFR: Case Studies of Miracles, Mistakes, and a Thousand Pens
Jared M. Skowron, ND Miracles Lori was on the verge of tears. Her son Nathan was 9 years old, and they had been to see psychiatrists, neurologists, counselors, and specialists. The problem was that nobody had an answer. (This story starts the same for so many of our...
Glioma? Drink More Coffee
Jacob Schor, ND Patients often have an idea in their heads of what a healthier lifestyle is, and it is our job as their ND to burst the bubble and set them straight. I thought of this the other day as a 56-year-old man explained to me that he was feeling “crappy”...
Age Related Cognitive Decline: Evidence-Based Strategies for Prevention and Treatment of Age-Related Cognitive Decline
Part Two—Prevention and Treatment Pamela Hutchison, BSc, ND With the proportion of the population older than 65 years in rapid ascent, the burden on the Canadian and American healthcare systems due to age-related cognitive disorders will be immense. Conventional...
The Body Remembers and Bears the Burden – When Biography Becomes Biology
Dr. Paul Epstein, ND The body remembers what the mind forgets. -Jacob L. Moreno, MD, Founder of Psychodrama Our diseases tell a story not just of our cells and a diagnosis but of ourselves and our life histories. By taking the risk of listening, we may be led...
Evidence-Based Strategies for Prevention and Treatment of Age-Related Cognitive Decline
Pamela Hutchison, BSc, ND Age-related cognitive decline begins, remarkably, in the late 20s and early 30s. As we age, we lose brain function from cellular injury due to inflammation, toxin exposure, insufficient sleep, injury, and other noxious influences. The...
Homeopathic Management of Pediatric Bipolar Disorder
Tara Peyman, ND Current diagnosis of bipolar disorder among young children is 40 times greater than its prevalence 10 years ago.1 It is unclear whether this increase is a result of previous underdiagnosis, current overdiagnosis, or a true increase in incidence. A 2010...
Physical Medicine for Depression
Peter Bongiorno, ND, LAc The World Health Organization1 predicts that depression will become the second most burdensome disease in the next decade, with the greatest onus in North America and the United Kingdom. Major depression is present among 33.3% of patients in...
CYP2D6 and Tamoxifen: SSRIs Lessen Benefit
Jacob Schor, ND Current evidence suggests that selective serotonin reuptake inhibitors (SSRIs) may reduce the effectiveness of tamoxifen citrate in preventing breast cancer recurrence. This has special relevance because SSRIs are now widely prescribed to treat hot...
Archived Case Studies and Featured Content
Adam Livingston: The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
https://youtube.com/shorts/KiCTEZDh3mc
Dr. Bush Bradley And The Role of Histamine and Serotonin in Upper GI Motility
D Laura Chan Discusses The Fertility Factor No One Talks About: Men’s Energetic Health
Emma Pollon McLeod The importance of Communication between Naturopathic Doctors and Pharmacist
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Jillian Finker, ND Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Abstract: Clostridoides difficile infection or CDI...
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Myasthenia Gravis and the Intestinal Microbiome: Naturopathic Translation into Clinical Practice
Jacob Schor, ND, FABNO Emerging research links gut dysbiosis and low butyrate production to myasthenia gravis. This article explores how naturopathic medicine can translate these findings into safe, patient-centered interventions. Abstract Emerging research suggests...
Akkermansia muciniphila: Clinical Insights on a Next-Generation Probiotic
Sara Love, ND A clinician’s guide to when—and when not—to use A. muciniphila: evidence for gut-barrier support, metabolic and immune effects, pasteurized vs live formulations, and patient selection. Abstract Akkermansia muciniphila is an emerging “next-generation”...
Functional Fermentation: Naturopathic Treatment of Entamoeba histolytica
Lauren Geyman, ND This case highlights how a naturopathic protocol—combining antiparasitic botanicals, targeted probiotics, and fermented foods—successfully eradicated Entamoeba histolytica while restoring gut balance and reducing inflammation. Abstract: Infection...
Early MASH Reversal: Mediterranean Diet and Naturopathic Co-Management
Anna Kolomitseva, ND A 51-year-old woman with severe steatosis and minimal fibrosis achieved early liver and metabolic improvements through a Mediterranean-style diet, low-impact activity, sleep support, and adjunctive nutraceuticals co-managed with conventional...
The Silent Toll: How Celiac Disease Drives Psychiatric and Neurological Disorders
Christine Bowen, ND, FABNG Abstract Celiac disease (CD) is increasingly recognized as a systemic autoimmune condition whose psychiatric and neurological manifestations often precede or overshadow gastrointestinal symptoms. Evidence demonstrates strong associations...
The Gut–Brain Axis: How the Nervous System Shapes Gut Health
Maura Henninger, ND Understanding the gut–brain connection reveals how stress, the autonomic nervous system, and the microbiome shape digestion, immunity, and emotional well-being—and how naturopathic care can restore balance. Abstract The gut–brain axis is a dynamic...
Clinical Commentary: Climate Change, Tick-borne Illness, and the Shifting Landscape of Clinical Practice
Lynn Klassen, ND Carolyn Mukai, ND Rising temperatures and changing habitats are driving the spread of Lyme disease and co-infections into new regions—challenging outdated risk maps, diagnostic tools, and clinical assumptions. Abstract Climate change is expanding the...
Restoring Cellular Integrity: Phospholipid Therapy as a Key Treatment of Refractory Tick-Borne Disease
Melanie Stein, ND A clinical case highlights how intravenous phosphatidylcholine and targeted membrane repair strategies supported lasting recovery in a patient with refractory Lyme and co-infections. Abstract This case describes a 47-year-old female high school...
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Featured News
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Naturopathic Doctor Continues Walk Across USA for Health Equity
Fargo, ND - Dennis Godby, 69, ND, MA, a Sacramento, CA-Licensed Naturopathic Doctor (ND), to raise awareness across the USA of significant health disparities, and support the “Health Equity,” movement, will continue his inspiring 756 mile walking trek across America...




