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Pamela Frank Micronutrient Deficiencies and Glucose Dysregulation
Lara Briden A Troubleshooting Approach to Insulin Resistance
Dr. Frasier And The Health Impacts of Microplastics
Is Heart Failure with Reduced Ejection Fraction Reversible? A Case-Based, Integrative Approach
S.A Decker Weiss, NMD, FASA, PLC A complex ischemic cardiomyopathy case exploring myocardial recovery through guideline-directed medical therapy, device support, metabolic optimization, and experimental regenerative adjuncts. Abstract This case report examines...
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Featured Article | Insomnia/Sleep Medicine
Melatonin & Glucose Homeostasis
A Complex Relationship GINA BROWN RICK BHIM, ND, CCNM Type 2 diabetes (T2DM) is a global health concern, affecting over 462 million individuals worldwide.1 It is a widely common condition in clinical practice and is a significant burden on the healthcare...
Exclusive Content | Insomnia/Sleep Medicine
As Health Goes, So Goes Sleep
Sleeping Disorders Among the Elderly Catherine Darley, ND It is commonly thought that as people age their sleep worsens. But is this true? Does it have to be? The answer is both yes and no. Some research has found that healthy elderly people sleep as well as healthy...
Women’s Sleep Through the Ages
Catherine Darley, ND Women’s sleep is uniquely influenced by hormonal changes throughout their life span. Generally, it is found that women have more sleep-related complaints than men, although women have better sleep quality. Women overall take less time to fall...
Syndrome Z: Apnea’s Metabolic Syndrome Expert Interview With Virend K. Somers, MD, Mayo Clinic
Mark Swanson, ND The best prescription for prevention is often a simple one: for the conditions described herein, it would be getting a good night’s sleep. But for many, that 8 hours of uninterrupted z’s has become a wishful event. By far, the most common sleep...
The Spirit That Resides in the Heart
Robin DiPasquale, ND, RH(AHG) Heart 7, Shen Men 神門 “Spirit Gate” In Taoism, shen men refers to the eyes, which reflect the presence and strength of the Spirit, the place where the Spirit enters and exits.1(pX) When a patient tells the physician that he or she is...
Hidden Causes of Insomnia
Bradley Bush, ND Insomnia is one of the most common complaints heard by healthcare practitioners. In 2008, researchers at Oregon Health & Science University, Portland, published a review article on insomnia that estimated its prevalence to be about 30% to 50%...
Sleeping Like a Baby
Catherine Darley, ND Does the phrase ‘Sleeping like a baby’ bring up pictures in your mind of a baby sleeping deeply? Or does it bring images of a crying baby who’s been up every 2 hours all night? Somehow, both of these pictures come to mind for me. Sleep problems...
The Connection Between ADHD and Obstructive Sleep Apnea: Naturopathic Approach and Treatment
Stacy Bowker, ND As NDs, we are taught to find and treat the cause of our patients’ symptoms. In the case of children presenting with attention deficit hyperactivity disorder (ADHD), there can be a variety of individual causes and more commonly, multiple causes that...
Pain Disrupts Sleep… The Sleep that Eases Pain
Catherine Darley, ND How many of your chronic pain patients have difficulty sleeping? Does this sleep disturbance contribute to their pain? In a word, yes. It has been found that sleep loss itself is hyperalgesic, and that when chronic pain patients sleep better their...
Archived Case Studies and Featured Content
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
RAZI BERRY Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Quantum Energy Field and Its Effects on Cellular ATP Production Rates in Human Cells
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Quantum Upgrade based on Leela Quantum technology, influences adenosine triphosphate (ATP) production in human cell lines. This double-blind...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
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Featured News
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
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