An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...

Trending Articles
Integrative Management of Postural Orthostatic Tachycardia Syndrome (POTS) Following COVID-19: A Case-Based, Longitudinal Approach
Dr. Adelena Izold, ND A systems-based framework addressing autonomic dysfunction, gut–brain signaling, endocrine balance, and metabolic resilience in post-viral dysautonomia. This case report describes the integrative management of a 36-year-old female with post-viral...
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
Dr. Vy Simeles, ND, Restorative Health Clinic A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Abstract This case report details the recovery of a...
Infection, Neuroinflammation, and Immune Dysregulation: The Clinical Overlap of Lyme Disease and PANS/PANDAS and a Path to Healing
Understanding the clinical overlap between vector-borne infections and pediatric acute-onset neuropsychiatric syndromes—and a systems-based integrative path to healing. Dr. Myriah Hinchey, ND, FMAPS Abstract This article examines the biological overlap between Lyme...
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Featured Article | Pain Medicine
Amyotrophic Lateral Sclerosis
Addressing Mitochondrial Alterations in C9orf72-ALS SAMANTHA PRYOR, ND Last year my first submission to NDNR was about microbiome alterations found in amyotrophic lateral sclerosis (ALS). I consider that article is essential reading for any clinician who...
Exclusive Content | Pain Medicine
Neurotransmitter Immune Effects: A Whole-Body Approach
Bradley Bush, ND As students of the nervous system, neurologists are master conventional diagnosticians. Some continue training and become neurosurgeons. Major neurological conditions and diseases seen by neurologists include multiple sclerosis, cerebral palsy,...
Pain, Scars and Neural Therapy
Tolle Causam Hal Brown, ND, DC, RAc “Maybe I should find another doctor; one who realizes the importance of scars.” (Rasmenia Massoud, Human Detritus) Over 20 years ago I attended an IV course taught by Dr Garrett Swetlikoff, which concluded with an introduction to...
Flavocoxid: A Botanical Extract Acts as a Balanced Inhibitor of Multiple Inflammatory Pathways
David M. Brady, ND, DC, CCN, DACBN Introduction There is great concern in the medical community over the excessive use of both non-steroidal anti-inflammatory drugs (NSAID) such as COX-2 inhibitors, and steroidal anti-inflammatory medications. There is also concern...
Botanical Therapies for Headaches
Jillian Stansbury, ND Headache Pathophysiology and Botanical Considerations Headache is one of the most common medical complaints treated in general clinical practices and is a significant public health burden, in terms of suffering, disrupted family interactions, and...
Oh No, Not That!
JOSEPH KELLERSTEIN, ND James phoned for a consult the other day. He had just had a vasectomy and was suffering a few postoperative consequences (how clinical of me). Do not get me wrong; I certainly did feel sympathy. In fact, I squirmed a bit with the description. I...
Nature Cure Clinical Pearls: Bleeding, Wounds, and Ulcers
Sussanna Czeranko, ND, BBE By these ulcers nature indicates her desire to excrete impure matter, and she only requires a little help. -Friedrich Bilz, 1898, p. 841 The greatest importance should be paid to keeping the wound perfectly clean. -Benedict Lust,...
What a Pain!
Joseph Kellerstein, DC, ND As you will see, Joe has been a victim of the finest medical treatment money could buy. Drugs can be a lifesaver, but occasionally those risks we all tend to ignore really happen. When they do, we might sit and wonder: why was it done in the...
Severe Disc Extrusion and Resolution by Prolotherapy
David Tallman, DC, ND The spinal disc allows vertebrates to enjoy an incredible amount of freedom of movement. This freedom of movement can become greatly hampered when the disc becomes adversely affected. Spinal disc disorders (SDDs) are an extremely common...
Archived Case Studies and Featured Content
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
Three pigs
Razi Ann Berry, Publisher Before medicine had metrics, it had stories built on observation that carried clinical truths in plain words. One of them still teaches a rule of clinical success. Build foundations, then treat. The Three Little Pigs understood the...
Your n=1 study doesn’t count.
Razi Ann Berry, Publisher After 20 years publishing NDNR monthly, I've heard this dismissal of case reports countless times. But I've come to believe we're overlooking something critical: Medicine has always been built on careful observation of individual...
New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
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Featured News
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...






