Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...

Trending Articles
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
Featured Article | Pain Medicine
Pathological Brain Patterns: The Often Forgotten Cause of Chronic Pain Conditions
Jody Stanislaw, ND Chronic pain, chronic fatigue, fibromyalgia, and long COVID are complex conditions with diverse yet overlapping symptoms, without a clear path for healing. Body work, counseling, acupuncture, and support groups, while helpful, often do not bring...
Exclusive Content | Pain Medicine
Curcumin: A Potential Powerhouse for RA Treatment
Holly Lucille, ND, RN In conventional practices, NSAIDs and glucocorticoids are used the most frequently for RA treatment, but they also bring with them a host of side effects, especially in long-term use. Possible adverse effects include stomach and liver damage,...
Tolle Totum: Advil is Safe, Right?
Shannon Estrada, ND Ibuprofen drugs and aspirin all belong to a class of drugs called nonsteroidal anti-inflammatories, or NSAIDs. As most know, these drugs are regularly used to reduce pain. In fact, according to a 2002 survey, 34% of the US population reported using...
Chronic Pain & Gut-Joint Axis
Aoife Earls, MSc, ND Abstract Chronic pain affects millions worldwide and is often treated with long-term NSAID therapy, which can compromise gastrointestinal (GI) integrity and exacerbate inflammation through increased intestinal permeability. Mounting evidence...
Fibromyalgia: A Case for Nature Cure in a 43-year-old Female
Kiran Khaira, MA Jennifer Brusewitz, ND Fibromyalgia is a common cause of chronic musculoskeletal pain, affecting approximately 2-8% of the population, predominantly females, with the prevalence increasing with age. The pain is usually accompanied by a multitude of...
The Smell of Pain
The Power of Olfaction in the Relief of Pain Sarah A. LoBisco, ND According to the American Academy of Pain Management (AAPM), millions of Americans suffer from pain. In fact, chronic pain affects more of the population than diabetes, heart disease, and cancer...
Topical Castor Oil
An Age-Old Remedy Provides Powerful Pain Relief Emily Telfair, ND My personal relationship with the castor plant began over 8 years ago when I was gifted a small castor seedling from my neighbor, an amateur horticulturist. Over the course of that summer, I watched my...
Physical Medicine for Migraine
Case Study Shows the Power of Cervical Adjustments and Trigger-Point Release Student Scholarship – Honorable Mention Case Study Robyn Prescott, BA, BINM Alana Shaw, bsc, ND According to the International Headache Society guidelines, the Global Burden of Disease Survey...
Glutamine: A Solution for Chemotherapy-Induced Peripheral Neuropathy?
Malea MacOdrum, NCNM Loch chandler, ND, Msom, lac Student Scholarship – Honorable Mention Case Study Peripheral neuropathy is a serious and often treatment-limiting side effect of several common cancer chemotherapeutics. Aside from impacting activities of daily living...
Archived Case Studies and Featured Content
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. Short Description This article explores estrogen metabolism...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. Short Description This case report details the successful resolution of anxiety,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
A Somatic Approach to Stage 5 Chronic Kidney Disease: Unbinding Fear and Grief from the Renal System
Dr. Erin Hayford, ND A naturopathic case exploring how structured somatic medicine can support nervous system regulation, emotional processing, and quality of life alongside conventional care in end-stage renal disease. This case report examines the integration...
Approaching Idiopathic Neuropathy: A Naturopathic Strategy Beyond Diabetes
Dr. Jason Porter, NMD A clinical overview of diagnosing and treating non-diabetic neuropathy through root-cause evaluation, including autoimmunity, infections, biotoxin exposure, and small fiber nerve pathology. Abstract This article explores a naturopathic...
Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body
Allison Creech, M.Ed., ND An in-depth exploration of how somatic awareness, interoception, and relational neuroscience can support nervous system regulation, authenticity, and healing in clinical practice. Abstract This article examines mind-body medicine as a...
Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
Dr. Nicole Roberts, ND A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Abstract In this case report, we see a 48-year-old female,...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
Dr. Leslie Solomonian, ND An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Abstract This article examines...
Borage (Borago officinalis): Botanical Ally for Courage, Self-Expression, and the Restoration of Self-Love
An integrative exploration of borage’s traditional uses, phytochemistry, and clinical applications in supporting self-compassion, stress resilience, and emotional regulation in naturopathic practice. Dr. Katelyn Mudry, ND, MSc Introduction Over the past year,...
Lavender Essential Oil and Anxiety Management: A Case Study
A case-based examination of oral lavender essential oil as a non-pharmaceutical intervention for generalized anxiety disorder in a patient seeking evidence-informed, integrative care. Dr. Jennifer Brusewitz ND Abstract This case study explores the use of a...
Olive Oil and Mental Health: A Scoping Review of Depression, Anxiety, and Stress Outcomes
A comprehensive scoping review explores how olive oil and its bioactive constituents may influence depression, anxiety, stress, and other mental health outcomes across clinical trials, epidemiological research, and preclinical models. Dr. Monique Aucoin ND MSc Vanessa...
Desperate patients are looking for you
Right now, someone in your community is Googling "how to get off antidepressants safely."They're not alone. Searches for "antidepressant withdrawal" are up 200%. In Canada, taper-related searches have increased 160 to 180% over the last few years.They're...
New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes
Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery. A...
Borage (Borago officinalis): Botanical Ally for Courage, Self-Expression, and the Restoration of Self-Love
An integrative exploration of borage’s traditional uses, phytochemistry, and clinical applications in supporting self-compassion, stress resilience, and emotional regulation in naturopathic practice. Dr. Katelyn Mudry, ND, MSc Introduction Over the past year,...
Lavender Essential Oil and Anxiety Management: A Case Study
A case-based examination of oral lavender essential oil as a non-pharmaceutical intervention for generalized anxiety disorder in a patient seeking evidence-informed, integrative care. Dr. Jennifer Brusewitz ND Abstract This case study explores the use of a...
Olive Oil and Mental Health: A Scoping Review of Depression, Anxiety, and Stress Outcomes
A comprehensive scoping review explores how olive oil and its bioactive constituents may influence depression, anxiety, stress, and other mental health outcomes across clinical trials, epidemiological research, and preclinical models. Dr. Monique Aucoin ND MSc Vanessa...
Desperate patients are looking for you
Right now, someone in your community is Googling "how to get off antidepressants safely."They're not alone. Searches for "antidepressant withdrawal" are up 200%. In Canada, taper-related searches have increased 160 to 180% over the last few years.They're...
New Research Shows Multi-Ingredient Cortisol Formula Improves Stress, Sleep, and Mood Outcomes
Vital Nutrients Releases Clinical Findings on Plant-Based Cortisol Balance Vital Nutrients has released new research highlighting the benefits of Cortisol Balance, a plant-based dietary supplement formulated to support healthy energy, stress response, and recovery. A...
Microplastics and Nanoplastics: Emerging Health Risks and Clinical Implications
Frasier Smith, ND Abstract Understanding how persistent plastic particles infiltrate human physiology—and what clinicians can do to help patients mitigate exposure and health impacts. Micro- and nanoplastic exposure is now ubiquitous, with growing evidence linking...
Quantum Energy Field and Its Effects on Cellular ATP Production Rates in Human Cells
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Quantum Upgrade based on Leela Quantum technology, influences adenosine triphosphate (ATP) production in human cell lines. This double-blind...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
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Featured News
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...





