Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
TERESA NEFF, ND, CLE You may have heard people speak of attention-deficit/hyperactivity disorder (ADHD) as a superpower. Its many positive aspects, such as creativity, curiosity, hyper-focus, perseverance, and energy, can and should outweigh the...
Erica Peirson, ND Down syndrome (DS) is one of the most common congenital anomalies worldwide, affecting approximately 14 in 10 000 live births.1 The syndrome occurs as a result of extra genetic material, full or partial, from chromosome 21. This additional genetic...
Tara Skye Goldin, ND Many of us are treating children with Asperger syndrome, otherwise known as autism spectrum disorder (ASD). The most recent statistic that I read is that 1 in 54 boys is now considered to have ASD.1 This is a significant increase over the past few...
Joseph Kellerstein, DC, ND Cheryl has been a patient off and on since she was about 3 years old. She is now 17. She was seen 3 weeks ago for the second time after she had not responded to a couple of prescriptions for her acne condition. I want to start this story...
Diagnosis and Treatment Protocols for Sleep Disorders Lisa Watson, ND Insufficient sleep is a common and often chronic condition in adolescence. It is estimated that between 25% and 45% of adolescents in the United States fail to obtain adequate sleep1,2 and that...
Eric Yarnell, ND Phimosis occurs when the foreskin is excessively tight and cannot be readily retracted off the glans. Phimosis is a physiological state until childhood, when the foreskin normally becomes readily retractable. In some cases, pathological phimosis...
Jessica Mitchell, ND A 6-year-old boy presents to your clinic with daily stomach pain and frequent vomiting. Eating has always been an issue for this child. There is a strong family history of atopy, and the child has had eczema and suffers from environmental...
Jillian Stansbury, ND I first moved to the Pacific Northwest in the early 1980s to attend National College of Natural Medicine, Portland, Oregon, and found a wooded rural home with a large friendly family next door. On getting to know the neighbors a bit, they were...
A Clinical Roundup of New Recommendations for Anticipatory Guidance Setareh Tais, ND Deborah Gleisner, ND Well-child care is an integral aspect of primary care for the pediatric population. The American Academy of Pediatrics and the Bright Futures promotion suggest...
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
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Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...
