Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...

Trending Articles
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Post-Pandemic Clinical Medicine – Addressing Long-COVID and Vaccine Injuries
An evidence-informed, dysfunction-based approach to evaluating spike protein effects, comorbidities, coagulation abnormalities, immune dysregulation, and mitochondrial dysfunction. Paul S. Anderson, NMD Abstract This clinical update summarizes a structured framework...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Featured Article | Women’s Health
Differentiating Polycystic Ovarian Syndrome and Non-Classical Adrenal Hyperplasia
A closer look at distinguishing PCOS from NCCAH in reproductive-age women, including diagnostic criteria and treatment approaches. By Kelly Simms ND, CNS, FABNE This article explores the clinical overlap between Polycystic Ovarian Syndrome (PCOS) and Non-Classical...
Exclusive Content | Women’s Health
Here We Go Again
Joseph Kellerstein, ND As you may remember, several months ago I treated a longtime patient for an unusual presentation of vaginitis. For this article, we will call her Susan. She responded very nicely to Cantharis. That particular episode so fascinated me that of...
Post-Pill Amenorrhea
Lindsay Martens, ND Post-pill amenorrhea is a frustrating adverse effect of using hormonal birth control. The use of hormonal contraceptives is on the rise and is expected to continue to increase as more young people age. In Canada, 72% of married women are using a...
Planning for a Healthy Pregnancy
Ann Lovick, ND When patients come into my office to discuss fertility, the first thing I tell them is to start acting like they are pregnant. This means that they need to be conscious of everything they put in their mouth and decide whether it is good for baby. The...
Just Scratching an Itch
Joseph Kellerstein, DC, ND Our emerald green, leaf-sitting friend above is known for homeopathic purposes as Cantharis vesicatoria (commonly known as the source of Spanish fly). He has a rather interesting past, as you may have heard, having been used from Hippocrates...
Supporting the Luteal Phase With Integrative Medicine
Maintenance of Early Pregnancy Fiona McCulloch, BSc, ND, CEFP The luteal phase is the stage of a woman’s cycle beginning at the time of ovulation and ending when the menses begin. During this time, the follicle undergoes its dramatic transformation into the corpus...
Treating PCOS Acne From the Inside Out
Cause and Effect Stacey Shillington, ND According to the principles of naturopathic medicine, the root cause of a condition must be treated as opposed to simply masking the presenting symptoms. Acne is one of the most palliated conditions in our society, and to follow...
Walking a Tightrope
Joseph Kellerstein, DC, ND I just got off the phone with a lovely lady whom I had not spoken to for about a year since our previous appointment. The result was so striking to me in the way of a good teaching point that I wanted to share my learning with all of you....
Melatonin Chronosynergy, Women, and Aging
The Expert Report Interview with Paula Witt-Enderby, PhD and Judith Balk, MPH, MD Mark Swanson, ND The concept of achieving therapeutic “synergy” is fundamental to the understanding of healing in a functional-naturopathic medicine practice. I have often postulated...
Archived Case Studies and Featured Content
Mediterranean Diet and Olive Oil in Women’s Health: Clinical Evidence and Applications
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Naturopathic Dementia Prevention: Clinical Strategies for Neurodegeneration
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
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Featured News
Alcohol Use and Nutrient Deficiency: A Self-Reinforcing Cycle
Research shows the relationship between alcohol use and nutrient depletion is bi-directional. Chronic drinking depletes key nutrients, and pre-existing deficiencies increase vulnerability to alcohol’s effects. Alcohol use typically begins early. The average age of...
Depression Appears 8 Years Before Pain Begins
Study Confirms Naturopathic Understanding of Depression-Pain Connection A 21-year longitudinal study tracking over 7,300 adults has documented that depression symptoms begin rising significantly up to eight years before pain develops. Published in eClinicalMedicine by...




