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Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
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Table of Contents | 2020 | March
Trauma, the Gut, & Autoimmunity: Novel Treatments for Trauma-Associated Autoimmunity
Naturopathic Perspective CATHERINE CLINTON, ND Sixty-percent of children experience trauma before the age of 16 years, according to a recent statewide survey.1 This study, which followed 1500 children for a period of 25...
Chronic Autoimmune Neutropenia: Case Study of a 4-Year-Old Female
Tolle Totum ELISABETH BASTOS, BSC, ND, RACU Neutrophils are known for their important role in fighting extracellular bacteria and fungal infections.1 They are involved in innate immunity via their recruitment and activation...
Notes from the Field: December, 2019
Nature Cure Clinical Pearls Jared L. Zeff, ND, VNMI, LAc The following is a not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the...
Dialing Up the Vis, Part 3
The Vital Conversation James Sensenig, ND This is the third part of a 3-part article from The Vital Conversation that took place on June 22, 2016. It is part of a new series of articles in NDNR that is based on transcripts of conversations that occurred on Wednesdays...
Public Sector Higher Ed: Slippery Slope or the Next Best Path?
Education David J. Schleich, PhD We’ve been sparring with the biomedicine industry all along the professional formation continuum (education, research, licensing) for a very long time. We have also been joining some aspects of the mainstream’s strategies for a...
Platelet-Rich Plasma (PRP)
Regenerative Medicine Fred G. Arnold, DC, NMD Platelet-Rich Plasma (PRP) is the third topic in my series about regenerative medicine treatments for painful musculoskeletal conditions. This regenerative injection procedure was originally used in 1987 following...
Fatigue Due to Mold Exposure: Pathophysiology
Tolle Causam Lauren Tessier, ND Illness resulting from mold and mycotoxin exposure is gaining more traction and attention. As the paradigm shift occurs, mold and mycotoxin-induced illness (MMII) should be brought to the forefront of clinical education, both in school...
Kratom: Miracle Herb or Public Health Danger?
Naturopathic Perspective Saul Marcus, ND Mitragyna speciosa (common name, kratom) is an herb from Southeast Asia. Traditionally, it has been used by workers to help them have more stamina during long workdays. A tea would be brewed from leaves, and consumed throughout...
An Integrative Approach: Case Study of Comorbid Major Depressive Disorder & T1DM
Tolle Totum Jaclyn Graham, BSc, ND The prevalence of depression in type 1 diabetic patients may be 3 times higher than that of non-diabetic patients in the general population, while 40% of patients with type 1 diabetes also have anxiety.1 The consequences of...
Low-Dose Lithium: An Effective Treatment for Mood Disorders
Tolle Causam Nicole Cain, ND, MA Pharmaceutical lithium carbonate is widely considered one of the most effective medications in psychiatry for treating bipolar depression. However, due to the potentially toxic effects of lithium at high doses, many doctors are...
Mood Disorders: Safe, Effective, and Natural Solutions
Vis Medicatrix Naturae Todd A. Born, ND, CNS Mood disorders are mental health issues that primarily impact a person’s emotional state; an affected person may experience periods of extreme happiness, extreme sadness, or both, that last at least several weeks.1 In the...
Archived Case Studies and Featured Content
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
Chemotherapy-induced peripheral neuropathy can persist long after cancer treatment, affecting pain, balance, function, and quality of life. This review examines evidence-informed strategies for CIPN, including Mediterranean-style nutrition, exercise, acupuncture, duloxetine, cryotherapy and compression, while identifying commonly used supplements that lack benefit or may worsen neuropathy.
Care Beyond the Cure: An Integrative Approach to Palliative Care
Palliative care is not about abandoning treatment or losing hope—it is about adding another layer of support. This article explores an integrative, interdisciplinary approach that introduces symptom management, quality-of-life support, advance care planning, and emotional and spiritual care early in the course of serious illness.
When Rib Pain Comes from the Spine: Thoracic Radiculopathy and Targeted Platelet-Based Treatment
After 2 years of persistent right costal-margin pain, negative visceral evaluations, and unsuccessful conservative treatment, neurodynamic testing and targeted examination localized a suspected T10 radicular source with additional thoracic articular and peripheral neural involvement. A single image-guided, multi-structure platelet-based intervention was followed by substantial and durable improvement in pain and function.
Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report
Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Custom Publishing
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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